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Page 1
Cardiotoxicities of Non-Chemotherapeutic Metastatic Breast Cancer Treatments.
Soltani M, Sokoloff LJ, Fradley MG. Soltani M, et al. Curr Oncol Rep. 2023 Aug;25(8):923-935. doi: 10.1007/s11912-023-01427-z. Epub 2023 May 30. Curr Oncol Rep. 2023. PMID: 37249834 Review.
PURPOSE OF REVIEW: Although mortality rates have declined significantly in recent years, breast cancer remains the second most common cause of cancer death in women, with rates significantly higher among women with metastatic disease. New therapeutic agents h …
PURPOSE OF REVIEW: Although mortality rates have declined significantly in recent years, breast cancer remains the second most …
5-Oxoproline prevents doxorubicin-induced cardiotoxicity and tumor growth.
Guo X, Jiang M, Tao Z, Dai H, Wu C, Wang Y, Wang Z, Wang X, Zhang Z, Qian K, Zeng S, Bei Y, Pu J. Guo X, et al. Redox Biol. 2025 Sep;85:103753. doi: 10.1016/j.redox.2025.103753. Epub 2025 Jul 5. Redox Biol. 2025. PMID: 40639202 Free PMC article.
BACKGROUND: Doxorubicin (DOX), a classical chemotherapeutic agent, faces significant limitations because of its well-documented risk of inducing cardiotoxicity. ...Given that alterations in metabolic pathways have been observed in both cardiovascular diseases and cancer …
BACKGROUND: Doxorubicin (DOX), a classical chemotherapeutic agent, faces significant limitations because of its well-documented risk …
An Olive Oil Mill Wastewater Extract Improves Chemotherapeutic Activity Against Breast Cancer Cells While Protecting From Cardiotoxicity.
Benedetto N, Calabrone L, Gutmańska K, Macrì N, Cerrito MG, Ricotta R, Pelosi G, Bruno A, Noonan DM, Albini A. Benedetto N, et al. Front Cardiovasc Med. 2022 Apr 14;9:867867. doi: 10.3389/fcvm.2022.867867. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35498037 Free PMC article.
In this study, we investigated the activities of polyphenol-rich extract from OMWW, A009, in cooperation with chemotherapy on two breast cancer cell lines, namely, BT459 and MDA-MB-231, in a cardio-oncology perspective. ...Our study demonstrates that t …
In this study, we investigated the activities of polyphenol-rich extract from OMWW, A009, in cooperation with chemotherapy on two breast …
Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4-dependent mechanism.
Szczepaniak P, Siedlinski M, Hodorowicz-Zaniewska D, Nosalski R, Mikolajczyk TP, Dobosz AM, Dikalova A, Dikalov S, Streb J, Gara K, Basta P, Krolczyk J, Sulicka-Grodzicka J, Jozefczuk E, Dziewulska A, Saju B, Laksa I, Chen W, Dormer J, Tomaszewski M, Maffia P, Czesnikiewicz-Guzik M, Crea F, Dobrzyn A, Moslehi J, Grodzicki T, Harrison DG, Guzik TJ. Szczepaniak P, et al. J Clin Invest. 2022 Jul 1;132(13):e149117. doi: 10.1172/JCI149117. J Clin Invest. 2022. PMID: 35617030 Free PMC article.
Cardiovascular disease is the major cause of morbidity and mortality in breast cancer survivors. Chemotherapy contributes to this risk. We aimed to define the mechanisms of long-term vascular dysfunction caused by neoadjuvant chemotherapy (NACT) and identify novel t …
Cardiovascular disease is the major cause of morbidity and mortality in breast cancer survivors. Chemotherapy contributes to t …
Cardio-oncology: role of echocardiography.
Villarraga HR, Herrmann J, Nkomo VT. Villarraga HR, et al. Prog Cardiovasc Dis. 2014 Jul-Aug;57(1):10-8. doi: 10.1016/j.pcad.2014.05.002. Epub 2014 May 20. Prog Cardiovasc Dis. 2014. PMID: 25081398 Review.
Current therapies for cancer have improved life expectancy of patients. Breast cancer and lymphoma survivors in up to 26% of cases can develop complications as a consequence of the chemotherapeutic and radiotherapeutic treatments. Echocardiography is a …
Current therapies for cancer have improved life expectancy of patients. Breast cancer and lymphoma survivors in up to 2 …
Role of Imaging in Cardio-Oncology.
Avelar E, Strickland CR, Rosito G. Avelar E, et al. Curr Treat Options Cardiovasc Med. 2017 Jun;19(6):46. doi: 10.1007/s11936-017-0546-2. Curr Treat Options Cardiovasc Med. 2017. PMID: 28474324 Review.
Recent advances in cancer treatment and research have greatly improved survival rates for patients with cancer. ...Certain chemotherapeutic agents, including anthracyclines and trastuzumab, have been linked to cardiotoxicity-induced cardiomyopathy in cance …
Recent advances in cancer treatment and research have greatly improved survival rates for patients with cancer. ...Certain …
Mechanisms of anthracycline-mediated cardiotoxicity and preventative strategies in women with breast cancer.
Varghese SS, Eekhoudt CR, Jassal DS. Varghese SS, et al. Mol Cell Biochem. 2021 Aug;476(8):3099-3109. doi: 10.1007/s11010-021-04152-y. Epub 2021 Apr 9. Mol Cell Biochem. 2021. PMID: 33835331 Review.
While anthracyclines (ACs) are a class of chemotherapeutic agents that have improved the prognosis of many women with breast cancer, it is one of the most cardiotoxic agents used to treat cancer. Despite their reported dose-dependent cardiotoxicity, AC …
While anthracyclines (ACs) are a class of chemotherapeutic agents that have improved the prognosis of many women with breast …
Cardiovascular Side Effects of Anthracyclines and HER2 Inhibitors among Patients with Breast Cancer: A Multidisciplinary Stepwise Approach for Prevention, Early Detection, and Treatment.
Mauro C, Capone V, Cocchia R, Cademartiri F, Riccardi F, Arcopinto M, Alshahid M, Anwar K, Carafa M, Carbone A, Castaldo R, Chianese S, Crisci G, D'Assante R, De Luca M, Franzese M, Galzerano D, Maffei V, Marra AM, Valente V, Giardino F, Mazza A, Ranieri B, D'Agostino A, Rega S, Romano L, Scagliarini S, Sepe C, Vriz O, Izzo R, Cittadini A, Bossone E, Salzano A. Mauro C, et al. J Clin Med. 2023 Mar 8;12(6):2121. doi: 10.3390/jcm12062121. J Clin Med. 2023. PMID: 36983126 Free PMC article. Review.
Therefore, it is mandatory to adopt cardioprotective strategies to minimize CV side effects and CVD in general in breast cancer patients. Cancer therapeutics-related cardiac dysfunction (CTRCD) is a common group of side effects of chemotherapeutics wid …
Therefore, it is mandatory to adopt cardioprotective strategies to minimize CV side effects and CVD in general in breast cancer …
Chemotherapy induced right ventricular cardiomyopathy; a systematic review and meta-analysis.
Theetha Kariyanna P, Kumar A, Jayarangaiah A, Shetty M, Chowdhury Y, Das S, Jayarangaiah A. Theetha Kariyanna P, et al. Front Cardiovasc Med. 2023 Aug 3;10:1103941. doi: 10.3389/fcvm.2023.1103941. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37600030 Free PMC article. Review.
Limited information exists regarding the impact of chemotherapeutic agents on the integrity and function of the right ventricle (RV). OBJECTIVES: The current metanalysis compared pre- chemotherapy versus post- chemotherapy RV parameters measured on 2D echocardiography in p …
Limited information exists regarding the impact of chemotherapeutic agents on the integrity and function of the right ventricle (RV). …
Cytotoxic-induced heart failure among breast cancer patients in Nigeria: A call to prevent today's cancer patients from being tomorrow's cardiac patients.
Anakwue R. Anakwue R. Ann Afr Med. 2020 Jan-Mar;19(1):1-7. doi: 10.4103/aam.aam_24_19. Ann Afr Med. 2020. PMID: 32174608 Free PMC article. Review.
The prevalence of breast cancer is increasing across Africa, and cytotoxics are some of the most common and best drugs used during management. ...The need for early involvement of cardiologists by oncologists to improve on the chemotherapeutic and cardiovascu …
The prevalence of breast cancer is increasing across Africa, and cytotoxics are some of the most common and best drugs used du …
20 results