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2008 1
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Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioning.
Heusch G. Heusch G. Circ Res. 2015 Feb 13;116(4):674-99. doi: 10.1161/CIRCRESAHA.116.305348. Circ Res. 2015. PMID: 25677517 Review.
Even ischemia/reperfusion in organs remote from the heart provides cardioprotection (remote ischemic conditioning). ...Although the translation of ischemic postconditioning and remote ischemic conditioning prot …
Even ischemia/reperfusion in organs remote from the heart provides cardioprotection (remote ischemic c
The pathophysiology of acute myocardial infarction and strategies of protection beyond reperfusion: a continual challenge.
Heusch G, Gersh BJ. Heusch G, et al. Eur Heart J. 2017 Mar 14;38(11):774-784. doi: 10.1093/eurheartj/ehw224. Eur Heart J. 2017. PMID: 27354052 Review.
We then go on to briefly characterize the cardioprotective phenomena of ischaemic preconditioning, ischaemic postconditioning, and remote ischaemic conditioning and their underlying signal transduction pathways. ...Currently, it appears t …
We then go on to briefly characterize the cardioprotective phenomena of ischaemic preconditioning, ischaemic postcondit …
Influence of Cardiovascular Risk Factors, Comorbidities, Medication Use and Procedural Variables on Remote Ischemic Conditioning Efficacy in Patients with ST-Segment Elevation Myocardial Infarction.
Pryds K, Hjortbak MV, Schmidt MR. Pryds K, et al. Int J Mol Sci. 2019 Jul 2;20(13):3246. doi: 10.3390/ijms20133246. Int J Mol Sci. 2019. PMID: 31269650 Free PMC article. Review.
Remote ischemic conditioning (RIC) confers cardioprotection in patients with ST-segment elevation myocardial infarction (STEMI). ...Although findings from studies evaluating influencing factors are often ambiguous, some but not all studie
Remote ischemic conditioning (RIC) confers cardioprotection in patients with ST-segment elevation myocardial
Ischaemic conditioning and reperfusion injury.
Hausenloy DJ, Yellon DM. Hausenloy DJ, et al. Nat Rev Cardiol. 2016 Apr;13(4):193-209. doi: 10.1038/nrcardio.2016.5. Epub 2016 Feb 4. Nat Rev Cardiol. 2016. PMID: 26843289 Free article. Review.
Apart from complete reperfusion, this method is the most powerful intervention known for reducing infarct size. The concept of ischaemic preconditioning has evolved into 'ischaemic conditioning', a term that encompasses a number of related endogenous cardi
Apart from complete reperfusion, this method is the most powerful intervention known for reducing infarct size. The concept of ischaemic
Effect of hyperglycaemia and diabetes on acute myocardial ischaemia-reperfusion injury and cardioprotection by ischaemic conditioning protocols.
Penna C, Andreadou I, Aragno M, Beauloye C, Bertrand L, Lazou A, Falcão-Pires I, Bell R, Zuurbier CJ, Pagliaro P, Hausenloy DJ. Penna C, et al. Br J Pharmacol. 2020 Dec;177(23):5312-5335. doi: 10.1111/bph.14993. Epub 2020 Mar 9. Br J Pharmacol. 2020. PMID: 31985828 Free article. Review.
These include one or more brief cycles of non-lethal ischaemia and reperfusion prior to the ischaemic event (ischaemic preconditioning [IPC]) or at the onset of reperfusion (ischaemic postconditioning [IPost]) either to the heart or to extracardiac organs ( …
These include one or more brief cycles of non-lethal ischaemia and reperfusion prior to the ischaemic event (ischaemic precond …
Long-term effect of remote ischemic conditioning on infarct size and clinical outcomes in patients with anterior ST-elevation myocardial infarction.
Verouhis D, Sörensson P, Gourine A, Henareh L, Persson J, Saleh N, Settergren M, Sundqvist M, Tengbom J, Tornvall P, Witt N, Böhm F, Pernow J. Verouhis D, et al. Catheter Cardiovasc Interv. 2021 Feb 15;97(3):386-392. doi: 10.1002/ccd.28760. Epub 2020 Feb 7. Catheter Cardiovasc Interv. 2021. PMID: 32034857
BACKGROUND: Conflicting evidence exists concerning the cardioprotective efficacy of remote ischemic conditioning as an adjunct to primary percutaneous intervention (PCI) in ST-elevation myocardial infarction (STEMI) and data on long-term …
BACKGROUND: Conflicting evidence exists concerning the cardioprotective efficacy of remote ischemic conditioning
Cardioprotection by remote ischemic conditioning and its signal transduction.
Kleinbongard P, Skyschally A, Heusch G. Kleinbongard P, et al. Pflugers Arch. 2017 Feb;469(2):159-181. doi: 10.1007/s00424-016-1922-6. Epub 2016 Dec 7. Pflugers Arch. 2017. PMID: 27928644 Review.
Remote ischemic conditioning by short repetitive cycles of ischemia/reperfusion on an extremity reduces infarct size and improves the prognosis of patients with reperfused myocardial infarction. ...Remote conditioning is obv
Remote ischemic conditioning by short repetitive cycles of ischemia/reperfusion on an extremity reduces infarct
Can Clinical and Functional Outcomes Be Improved with an Intelligent "Internet Plus"-Based Full Disease Cycle Remote Ischemic Conditioning Program in Acute ST-elevation Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention? Rationale and Design of the i-RIC Trial.
Zheng Y, Reinhardt JD, Li J, Hu D, Lin S, Wang L, Dai R, Fan Z, Ding R, Chen L, Yuan L, Xu Z, Cheng Y, Yan C, Zhang X, Wang L, Zhang X, Teng M, Yu Q, Yin A, Lu X; i-RIC Trial Collaboration Group. Zheng Y, et al. Cardiovasc Drugs Ther. 2020 Jun 30. doi: 10.1007/s10557-020-07022-9. Online ahead of print. Cardiovasc Drugs Ther. 2020. PMID: 32607820
Preliminary evidence suggests that remote ischemic conditioning (RIC) is a promising non-invasive intervention that may effectively and safely reduce myocardial infarct size, subsequent cardiac events and complications, and mortality. ...METHODS: The i …
Preliminary evidence suggests that remote ischemic conditioning (RIC) is a promising non-invasive intervention that may …
Ischaemic and hypoxic conditioning: potential for protection of vital organs.
Sprick JD, Mallet RT, Przyklenk K, Rickards CA. Sprick JD, et al. Exp Physiol. 2019 Mar;104(3):278-294. doi: 10.1113/EP087122. Epub 2019 Jan 24. Exp Physiol. 2019. PMID: 30597638 Free PMC article. Review.
NEW FINDINGS: What is the topic of this review? Remote ischaemic preconditioning (RIPC) and hypoxic preconditioning as novel therapeutic approaches for cardiac and neuroprotection. ...In this Symposium Report we highlight the potential applications of intermittent …
NEW FINDINGS: What is the topic of this review? Remote ischaemic preconditioning (RIPC) and hypoxic preconditioning as novel t …
Remote ischemic conditioning in ST-segment elevation myocardial infarction - an update.
Chong J, Bulluck H, Yap EP, Ho AF, Boisvert WA, Hausenloy DJ. Chong J, et al. Cond Med. 2018 Aug;1(5):13-22. Cond Med. 2018. PMID: 30338313 Free PMC article.
Acute myocardial infarction (AMI) and the heart failure (HF) that often results are among the leading causes of death and disability in the world. ...The endogenous cardioprotective strategy of remote ischemic conditioning (RIC), in which …
Acute myocardial infarction (AMI) and the heart failure (HF) that often results are among the leading causes of death and disa …
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