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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1981 4
1982 2
1983 2
1984 5
1985 4
1986 3
1987 5
1988 14
1989 24
1990 27
1991 56
1992 51
1993 81
1994 63
1995 85
1996 127
1997 139
1998 143
1999 155
2000 172
2001 189
2002 193
2003 235
2004 262
2005 302
2006 331
2007 375
2008 344
2009 398
2010 374
2011 447
2012 377
2013 423
2014 391
2015 486
2016 444
2017 435
2018 414
2019 406
2020 328
2021 118
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7,550 results
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Page 1
The protective role of curcumin in myocardial ischemia-reperfusion injury.
Mokhtari-Zaer A, Marefati N, Atkin SL, Butler AE, Sahebkar A. Mokhtari-Zaer A, et al. J Cell Physiol. 2018 Jan;234(1):214-222. doi: 10.1002/jcp.26848. Epub 2018 Jul 3. J Cell Physiol. 2018. PMID: 29968913 Review.
Coronary artery disease (CAD) is a well-known pathological condition that is characterized by high morbidity and mortality. The main pathological manifestation of CAD is myocardial injury due to ischemia-reperfusion (I-R). Currently, no e
Coronary artery disease (CAD) is a well-known pathological condition that is characterized by high morbidity and mortal
Beyond Reperfusion: Acute Ventricular Unloading and Cardioprotection During Myocardial Infarction.
Curran J, Burkhoff D, Kloner RA. Curran J, et al. J Cardiovasc Transl Res. 2019 Apr;12(2):95-106. doi: 10.1007/s12265-019-9863-z. Epub 2019 Jan 22. J Cardiovasc Transl Res. 2019. PMID: 30671717 Free PMC article. Review.
This review will focus on new clinical and pre-clinical data demonstrating that acute ventricular unloading prior to reperfusion by means of percutaneous left ventricular support devices reduces ischemia-reperfusion injury and limits infarct scar size. Emphas …
This review will focus on new clinical and pre-clinical data demonstrating that acute ventricular unloading prior to reperfusion by m …
Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioning.
Heusch G. Heusch G. Circ Res. 2015 Feb 13;116(4):674-99. doi: 10.1161/CIRCRESAHA.116.305348. Circ Res. 2015. PMID: 25677517 Review.
The conditioning phenomena provide such cardioprotection, insofar as brief episodes of coronary occlusion/reperfusion preceding (ischemic preconditioning) or following (ischemic postconditioning) sustained myocardial ischemia with reperfusion
The conditioning phenomena provide such cardioprotection, insofar as brief episodes of coronary occlusion/reperfusion p …
Untargeted metabolomics analysis of ischemia-reperfusion-injured hearts ex vivo from sedentary and exercise-trained rats.
Parry TL, Starnes JW, O'Neal SK, Bain JR, Muehlbauer MJ, Honcoop A, Ilaiwy A, Christopher P, Patterson C, Willis MS. Parry TL, et al. Metabolomics. 2018 Jan;14(1):8. doi: 10.1007/s11306-017-1303-y. Epub 2017 Dec 4. Metabolomics. 2018. PMID: 30104954 Free PMC article.
OBJECTIVES: To identify novel metabolic changes that occur parallel to these mitochondrial alterations, we performed non-targeted metabolomics analysis on hearts from sedentary and exercise-trained rats challenged with isolated heart ischemia-reperfusion injury (I/R …
OBJECTIVES: To identify novel metabolic changes that occur parallel to these mitochondrial alterations, we performed non-targeted metabolomi …
Cardioplegia and cardiac surgery: pharmacological arrest and cardioprotection during global ischemia and reperfusion.
Chambers DJ, Fallouh HB. Chambers DJ, et al. Pharmacol Ther. 2010 Jul;127(1):41-52. doi: 10.1016/j.pharmthera.2010.04.001. Epub 2010 Apr 14. Pharmacol Ther. 2010. PMID: 20398698 Review.
Recent patient demographic changes, with surgeons operating on older, sicker patients who have more severe and diffuse disease, potentially requires a more prolonged elective ischemia; hence, an improved myocardial protection would be of benefit. Several area …
Recent patient demographic changes, with surgeons operating on older, sicker patients who have more severe and diffuse disease, poten …
Pre-conditioning and postconditioning to limit ischemia-reperfusion-induced myocardial injury: what could be the next footstep?
Balakumar P, Rohilla A, Singh M. Balakumar P, et al. Pharmacol Res. 2008 Jun;57(6):403-12. doi: 10.1016/j.phrs.2008.05.006. Epub 2008 Jun 30. Pharmacol Res. 2008. PMID: 18586514 Review.
The brief episodes of ischemia and reperfusion given before prolonged ischemia and reperfusion denote pre-conditioning. ...In this review, we have critically discussed the mechanisms involved in the cardioprotective effects of pre- and postcondi …
The brief episodes of ischemia and reperfusion given before prolonged ischemia and reperfusion denote pre-condit …
Left Ventricular Unloading Before Reperfusion Promotes Functional Recovery After Acute Myocardial Infarction.
Esposito ML, Zhang Y, Qiao X, Reyelt L, Paruchuri V, Schnitzler GR, Morine KJ, Annamalai SK, Bogins C, Natov PS, Pedicini R, Breton C, Mullin A, Mackey EE, Patel A, Rowin E, Jaffe IZ, Karas RH, Kapur NK. Esposito ML, et al. J Am Coll Cardiol. 2018 Jul 31;72(5):501-514. doi: 10.1016/j.jacc.2018.05.034. J Am Coll Cardiol. 2018. PMID: 30049311 Free PMC article.
OBJECTIVES: This study tested the importance of LV unloading before reperfusion, explored cardioprotective mechanisms, and determined the late-term impact of primary unloading on myocardial function. ...CONCLUSIONS: The authors report for the first time that …
OBJECTIVES: This study tested the importance of LV unloading before reperfusion, explored cardioprotective mechanisms, and det …
Lipopolysaccharides Improve Mesenchymal Stem Cell-Mediated Cardioprotection by MyD88 and stat3 Signaling in a Mouse Model of Cardiac Ischemia/Reperfusion Injury.
Chu X, Xu B, Gao H, Li BY, Liu Y, Reiter JL, Wang Y. Chu X, et al. Stem Cells Dev. 2019 May 1;28(9):620-631. doi: 10.1089/scd.2018.0213. Epub 2019 Apr 11. Stem Cells Dev. 2019. PMID: 30808255 Free PMC article.
Bone marrow-derived mesenchymal stem cells (MSCs) improve cardiac function after ischemia/reperfusion injury, in part, due to the release of cytoprotective paracrine factors. ...WT and MyD88(-/-) MSCs with or without LPS pretreatment were infused into the coronar
Bone marrow-derived mesenchymal stem cells (MSCs) improve cardiac function after ischemia/reperfusion injury, in part, due to …
Cytochrome P450 and myocardial ischemia: potential pharmacological implication for cardioprotection.
Barau C, Ghaleh B, Berdeaux A, Morin D. Barau C, et al. Fundam Clin Pharmacol. 2015 Feb;29(1):1-9. doi: 10.1111/fcp.12087. Epub 2014 Sep 25. Fundam Clin Pharmacol. 2015. PMID: 24990103 Review.
CYP 2J2, CYP 2C8, CYP 2C9, CYP 4F) can play a role in the pathogenesis of ischemia-reperfusion. Moreover, various data indicate that microsomal CYP could represent a relevant target to develop pharmacological therapies to attenuate ischemia-reperfusion
CYP 2J2, CYP 2C8, CYP 2C9, CYP 4F) can play a role in the pathogenesis of ischemia-reperfusion. Moreover, various data indicat …
TNFalpha in atherosclerosis, myocardial ischemia/reperfusion and heart failure.
Kleinbongard P, Heusch G, Schulz R. Kleinbongard P, et al. Pharmacol Ther. 2010 Sep;127(3):295-314. doi: 10.1016/j.pharmthera.2010.05.002. Epub 2010 Jun 1. Pharmacol Ther. 2010. PMID: 20621692 Review.
TNFalpha is crucially involved in the pathogenesis and progression of atherosclerosis, myocardial ischemia/reperfusion injury and heart failure. The formation and release of TNFalpha and its downstream signal transduction cascade following activation of its t …
TNFalpha is crucially involved in the pathogenesis and progression of atherosclerosis, myocardial ischemia/reperfusion
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