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Characteristics of androgen deficiency in late-onset hypogonadism: results from the European Male Aging Study (EMAS).
Tajar A, Huhtaniemi IT, O'Neill TW, Finn JD, Pye SR, Lee DM, Bartfai G, Boonen S, Casanueva FF, Forti G, Giwercman A, Han TS, Kula K, Labrie F, Lean ME, Pendleton N, Punab M, Vanderschueren D, Wu FC; EMAS Group. Tajar A, et al. J Clin Endocrinol Metab. 2012 May;97(5):1508-16. doi: 10.1210/jc.2011-2513. Epub 2012 Mar 14. J Clin Endocrinol Metab. 2012. PMID: 22419720
CONTEXT: Late-onset hypogonadism (LOH) has been defined as a syndrome in middle-aged and elderly men reporting symptoms in the presence of low testosterone (T). ...DESIGN, SETTING, AND PARTICIPANTS: The design of the study included …
CONTEXT: Late-onset hypogonadism (LOH) has been defined as a syndrome in middle-aged and elderly men repo …
Low Free Testosterone Is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone.
Antonio L, Wu FC, O'Neill TW, Pye SR, Ahern TB, Laurent MR, Huhtaniemi IT, Lean ME, Keevil BG, Rastrelli G, Forti G, Bartfai G, Casanueva FF, Kula K, Punab M, Giwercman A, Claessens F, Decallonne B, Vanderschueren D; European Male Ageing Study Study Group. Antonio L, et al. J Clin Endocrinol Metab. 2016 Jul;101(7):2647-57. doi: 10.1210/jc.2015-4106. Epub 2016 Feb 24. J Clin Endocrinol Metab. 2016. PMID: 26909800
CONTEXT: During aging, total testosterone (TT) declines and SHBG increases, resulting in a greater decrease in calculated free T (cFT). ...CONCLUSIONS: Low cFT, even in the presence of normal TT, is associated with androgen deficiency-related symptoms. Normal …
CONTEXT: During aging, total testosterone (TT) declines and SHBG increases, resulting in a greater decrease in calculated free …