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Acromegaly in Carney complex.
Cuny T, Mac TT, Romanet P, Dufour H, Morange I, Albarel F, Lagarde A, Castinetti F, Graillon T, North MO, Barlier A, Brue T. Cuny T, et al. Pituitary. 2019 Oct;22(5):456-466. doi: 10.1007/s11102-019-00974-8. Pituitary. 2019. PMID: 31264077 Review.
PURPOSE: Carney complex (CNC) is a rare autosomal dominant syndrome, characterized by mucocutaneous pigmentation, cardiac, cutaneous myxomas and endocrine overactivity. It is generally caused by inactivating mutations in the PRKAR1A (protein kinase cAMP-depen …
PURPOSE: Carney complex (CNC) is a rare autosomal dominant syndrome, characterized by mucocutaneous pigmentation, cardi …
Dermatological and endocrine elements in Carney complex (Review).
Sandru F, Dumitrascu MC, Petca A, Carsote M, Petca RC, Paun DL. Sandru F, et al. Exp Ther Med. 2021 Nov;22(5):1313. doi: 10.3892/etm.2021.10748. Epub 2021 Sep 17. Exp Ther Med. 2021. PMID: 34630667 Free PMC article. Review.
Carney complex (CnuC) is a very rare, autosomal dominant, hereditary syndrome. ...A total of 5% of familial non-medullary thyroid cancer is syndromic, also including CNC. CNC-related thyroid frame includes: hyperthyroidism, follicular hyperplasia/adeno …
Carney complex (CnuC) is a very rare, autosomal dominant, hereditary syndrome. ...A total of 5% of familial non-medullary thyr …
Genetics of micronodular adrenal hyperplasia and Carney complex.
Tirosh A, Valdés N, Stratakis CA. Tirosh A, et al. Presse Med. 2018 Jul-Aug;47(7-8 Pt 2):e127-e137. doi: 10.1016/j.lpm.2018.07.005. Epub 2018 Aug 6. Presse Med. 2018. PMID: 30093212 Review.
The most common presentation of MiBAH is familial PPNAD as part of Carney complex (CNC) (cPPNAD). CNC, associated with multiple endocrine and non-endocrine neoplasias, was first described in 1985 in 40 patients, 10 of whom were familial cases. In 2000, …
The most common presentation of MiBAH is familial PPNAD as part of Carney complex (CNC) (cPPNAD). CNC, associate …
MEN1, MEN4, and Carney Complex: Pathology and Molecular Genetics.
Schernthaner-Reiter MH, Trivellin G, Stratakis CA. Schernthaner-Reiter MH, et al. Neuroendocrinology. 2016;103(1):18-31. doi: 10.1159/000371819. Epub 2015 Jan 9. Neuroendocrinology. 2016. PMID: 25592387 Free PMC article. Review.
We provide here a review of the clinical features and human molecular genetics of multiple endocrine neoplasia (MEN) type 1 and 4 (MEN1 and MEN4, respectively) and Carney complex (CNC). MEN1, MEN4, and CNC are hereditary autosomal dominant syndromes th …
We provide here a review of the clinical features and human molecular genetics of multiple endocrine neoplasia (MEN) type 1 and 4 (MEN1 and …
Cushing syndrome: uncovering Carney complex due to novel PRKAR1A mutation.
Zhang CD, Pichurin PN, Bobr A, Lyden ML, Young WF, Bancos I. Zhang CD, et al. Endocrinol Diabetes Metab Case Rep. 2019 Mar 21;2019:18-0150. doi: 10.1530/EDM-18-0150. Online ahead of print. Endocrinol Diabetes Metab Case Rep. 2019. PMID: 30897549 Free PMC article.
Carney complex (CNC) is a rare multiple neoplasia syndrome characterized by spotty pigmentation of the skin and mucosa in association with various non-endocrine and endocrine tumors, including primary pigmented nodular adrenocortical disease (PPNAD). ...Genet …
Carney complex (CNC) is a rare multiple neoplasia syndrome characterized by spotty pigmentation of the skin and mucosa …
PRKAR1A and Thyroid Tumors.
Pitsava G, Stratakis CA, Faucz FR. Pitsava G, et al. Cancers (Basel). 2021 Jul 30;13(15):3834. doi: 10.3390/cancers13153834. Cancers (Basel). 2021. PMID: 34359735 Free PMC article. Review.
Thyroid cancer, including both FTC and PTC, has been observed in patients with Carney Complex (CNC), a syndrome that is inherited in an autosomal dominant manner and predisposes to various tumors. CNC is caused by inactivating mutations in the tumor-su …
Thyroid cancer, including both FTC and PTC, has been observed in patients with Carney Complex (CNC), a syndrome that is …
MANAGEMENT OF ENDOCRINE DISEASE: Carney complex: clinical and genetic update 20 years after the identification of the CNC1 (PRKAR1A) gene.
Bouys L, Bertherat J. Bouys L, et al. Eur J Endocrinol. 2021 Mar;184(3):R99-R109. doi: 10.1530/EJE-20-1120. Eur J Endocrinol. 2021. PMID: 33444222 Review.
Described for the first time in 1985, Carney complex (CNC) is a rare dominantly inherited multiple neoplasia syndrome with almost full penetrance and characterized by both endocrine - primary pigmented nodular adrenocortical disease with Cushing's syndrome, a …
Described for the first time in 1985, Carney complex (CNC) is a rare dominantly inherited multiple neoplasia syndrome w …
Carney complex syndrome manifesting as cardioembolic stroke: a case report and review of the literature.
Chatzikonstantinou S, Kazis D, Giannakopoulou P, Poulios P, Pikou O, Geroukis T, Lyssikatos C, Stratakis CA, Bostanjopoulou S. Chatzikonstantinou S, et al. Int J Neurosci. 2022 Jul;132(7):649-655. doi: 10.1080/00207454.2020.1834393. Epub 2020 Nov 10. Int J Neurosci. 2022. PMID: 33027596 Review.
BACKGROUND: "Carney Complex (CNC) is a familial lentiginosis syndrome, caused by PRKAR1A mutations that lead to cyclic AMP-dependent protein kinase (PKA) signaling pathway abnormalities, predisposing to a variety of skin tumors, myxomas and endocrine tumors. …
BACKGROUND: "Carney Complex (CNC) is a familial lentiginosis syndrome, caused by PRKAR1A mutations that lead to cyclic …
Surgical Management of Carney Complex-Associated Pituitary Pathology.
Lonser RR, Mehta GU, Kindzelski BA, Ray-Chaudhury A, Vortmeyer AO, Dickerman R, Oldfield EH. Lonser RR, et al. Neurosurgery. 2017 May 1;80(5):780-786. doi: 10.1227/NEU.0000000000001384. Neurosurgery. 2017. PMID: 27509071 Free PMC article.
BACKGROUND: Carney complex (CNC) is a familial neoplasia syndrome that is associated with pituitary-associated hypersecretion of growth hormone (GH) (acromegaly). The underlying cause of pituitary GH hypersecretion and its management have been incompletely de …
BACKGROUND: Carney complex (CNC) is a familial neoplasia syndrome that is associated with pituitary-associated hypersec …
Failure to Thrive in the Context of Carney Complex.
Tirosh A, Auerbach A, Bonella B, Zavras PD, Belyavskaya E, Lyssikatos C, Meir K, Weiss R, Daum H, Lodish MB, Gillis D, Stratakis CA. Tirosh A, et al. Horm Res Paediatr. 2018;89(1):38-46. doi: 10.1159/000484690. Epub 2017 Nov 21. Horm Res Paediatr. 2018. PMID: 29161691 Free article.
BACKGROUND/AIMS: Carney complex (CNC) is a rare syndrome associated with multiple tumors and several other unique manifestations. We describe the clinical, genetic, and laboratory findings in a cohort of patients with CNC and failure to thrive (FTT). M …
BACKGROUND/AIMS: Carney complex (CNC) is a rare syndrome associated with multiple tumors and several other unique manif …
74 results