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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1918 1
1921 3
1922 3
1923 1
1924 1
1925 1
1928 1
1938 2
1947 3
1949 1
1950 4
1951 3
1952 7
1953 7
1954 4
1955 3
1956 3
1957 6
1958 4
1959 5
1960 7
1961 4
1962 6
1963 5
1964 10
1965 6
1966 3
1967 5
1968 11
1969 8
1970 10
1971 10
1972 3
1973 3
1974 15
1975 12
1976 20
1977 24
1978 24
1979 21
1980 26
1981 20
1982 26
1983 19
1984 29
1985 28
1986 25
1987 19
1988 28
1989 38
1990 45
1991 38
1992 60
1993 33
1994 36
1995 39
1996 29
1997 41
1998 43
1999 56
2000 61
2001 41
2002 61
2003 45
2004 56
2005 58
2006 64
2007 72
2008 71
2009 87
2010 106
2011 101
2012 110
2013 97
2014 129
2015 115
2016 130
2017 134
2018 140
2019 143
2020 78
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2,582 results
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Page 1
Physiology and pathophysiology of carnosine.
Boldyrev AA, Aldini G, Derave W. Boldyrev AA, et al. Physiol Rev. 2013 Oct;93(4):1803-45. doi: 10.1152/physrev.00039.2012. Physiol Rev. 2013. PMID: 24137022 Free article. Review.
Also the pathophysiological relevance of serum carnosinase, the enzyme actively degrading carnosine into l-histidine and β-alanine, is discussed. ...This paper summarizes a century of scientific exploration on the (patho)physiological role of carnosine and related c …
Also the pathophysiological relevance of serum carnosinase, the enzyme actively degrading carnosine into l-histidine and β-alanine, i …
Carnosine and the processes of ageing.
Hipkiss AR, Baye E, de Courten B. Hipkiss AR, et al. Maturitas. 2016 Nov;93:28-33. doi: 10.1016/j.maturitas.2016.06.002. Epub 2016 Jun 22. Maturitas. 2016. PMID: 27344459 Review.
It has been suggested that the endogenous dipeptide carnosine, also available as a food supplement, possesses anti-ageing activity and may achieve its reported age-alleviating effects via a number of mechanisms. Carnosine's possible anti-ageing mechanisms are …
It has been suggested that the endogenous dipeptide carnosine, also available as a food supplement, possesses anti-ageing activity an …
Carnosine and advanced glycation end products: a systematic review.
Ghodsi R, Kheirouri S. Ghodsi R, et al. Amino Acids. 2018 Sep;50(9):1177-1186. doi: 10.1007/s00726-018-2592-9. Epub 2018 Jun 1. Amino Acids. 2018. PMID: 29858687 Review.
Review articles, studies based on the components of carnosine and studies that were about the effects of carnosine on AGEs-induced changes were excluded. ...The mechanism by which carnosine prevents the formation of AGEs needs further investigation....
Review articles, studies based on the components of carnosine and studies that were about the effects of carnosine on AGEs-ind …
Carnosine protects cardiac myocytes against lipid peroxidation products.
Zhao J, Posa DK, Kumar V, Hoetker D, Kumar A, Ganesan S, Riggs DW, Bhatnagar A, Wempe MF, Baba SP. Zhao J, et al. Amino Acids. 2019 Jan;51(1):123-138. doi: 10.1007/s00726-018-2676-6. Epub 2018 Nov 17. Amino Acids. 2019. PMID: 30449006 Free PMC article.
Hence, to examine whether changes in the structure of carnosine could affect its aldehyde reactivity and metal chelating ability, we synthesized methylated analogs of carnosine, balenine (β-alanine-N(τ)-methylhistidine) and dimethyl balenine (DMB), and measured thei …
Hence, to examine whether changes in the structure of carnosine could affect its aldehyde reactivity and metal chelating ability, we …
Glycotoxins: Dietary and Metabolic Origins; Possible Amelioration of Neurotoxicity by Carnosine, with Special Reference to Parkinson's Disease.
Hipkiss AR. Hipkiss AR. Neurotox Res. 2018 Jul;34(1):164-172. doi: 10.1007/s12640-018-9867-5. Epub 2018 Feb 7. Neurotox Res. 2018. PMID: 29417441 Review.
By reacting with MG, carnosine may also prevent generation of the neurotoxin 1-acetyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (ADTIQ), which accumulates in PD and diabetic brains. It is suggested that carnosine's therapeutic potential could be explored v …
By reacting with MG, carnosine may also prevent generation of the neurotoxin 1-acetyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (A …
Carnosine's inhibitory effect on glioblastoma cell growth is independent of its cleavage.
Oppermann H, Purcz K, Birkemeyer C, Baran-Schmidt R, Meixensberger J, Gaunitz F. Oppermann H, et al. Amino Acids. 2019 May;51(5):761-772. doi: 10.1007/s00726-019-02713-6. Epub 2019 Mar 12. Amino Acids. 2019. PMID: 30863889
Moreover, we determined expression of carnosinases, the intracellular release of L-histidine from carnosine, and whether inhibition of carnosine cleavage attenuates carnosine's antineoplastic effect. ...In addition, we detected protein and mRNA express …
Moreover, we determined expression of carnosinases, the intracellular release of L-histidine from carnosine, and whether inhibition o …
Evaluation of liposomal carnosine in adjuvant arthritis.
Slovák L, Poništ S, Fedorova T, Logvinenko A, Levacheva I, Samsonova O, Bakowsky U, Pašková Ľ, Čavojský T, Tsiklauri L, Bauerová K. Slovák L, et al. Gen Physiol Biophys. 2017 Oct;36(4):471-479. doi: 10.4149/gpb_2017014. Epub 2017 Aug 24. Gen Physiol Biophys. 2017. PMID: 28836498
Liposomal carnosine could overcome the problems associated with direct application of this peptide. Anti-inflammatory and antioxidant effects of liposomal and non-liposomal carnosine in adjuvant arthritis were compared. ...Liposomal carnosine corrected more e …
Liposomal carnosine could overcome the problems associated with direct application of this peptide. Anti-inflammatory and antioxidant …
Evaluation of Carnosine Intervention in the Thy1-aSyn Mouse Model of Parkinson's Disease.
Bermúdez ML, Seroogy KB, Genter MB. Bermúdez ML, et al. Neuroscience. 2019 Jul 15;411:270-278. doi: 10.1016/j.neuroscience.2019.05.026. Epub 2019 May 22. Neuroscience. 2019. PMID: 31125602
Olfactory function was unaffected by carnosine treatment via either administration route. In contrast, intranasal carnosine prevented the normal decline in gait function seen in the challenging beam test in the Thy1-aSyn mice. Moreover, carnosine-treated Thy1 …
Olfactory function was unaffected by carnosine treatment via either administration route. In contrast, intranasal carnosine pr …
Carnosine and its possible roles in nutrition and health.
Hipkiss AR. Hipkiss AR. Adv Food Nutr Res. 2009;57:87-154. doi: 10.1016/S1043-4526(09)57003-9. Adv Food Nutr Res. 2009. PMID: 19595386 Review.
Carnosine's ability to react with deleterious aldehydes such as malondialdehyde, methylglyoxal, hydroxynonenal, and acetaldehyde may also contribute to its protective functions. ...Evidence for carnosine's possible protective action against secondary d
Carnosine's ability to react with deleterious aldehydes such as malondialdehyde, methylglyoxal, hydroxynonenal, and acetaldehy
Twenty-four Weeks of β-Alanine Supplementation on Carnosine Content, Related Genes, and Exercise.
Saunders B, DE Salles Painelli V, DE Oliveira LF, DA Eira Silva V, DA Silva RP, Riani L, Franchi M, Gonçalves LS, Harris RC, Roschel H, Artioli GG, Sale C, Gualano B. Saunders B, et al. Med Sci Sports Exerc. 2017 May;49(5):896-906. doi: 10.1249/MSS.0000000000001173. Med Sci Sports Exerc. 2017. PMID: 28157726 Clinical Trial.
No study has investigated the effects of prolonged supplementation on carnosine-related genes or exercise capacity. PURPOSE: This study aimed to investigate the effects of 24 wk of BA supplementation on muscle carnosine content, gene expression, and high-intensity c …
No study has investigated the effects of prolonged supplementation on carnosine-related genes or exercise capacity. PURPOSE: This stu …
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