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Enhanced effect of kappa-carrageenan on TNBS-induced inflammation in mice.
Wei W, Feng W, Xin G, Tingting N, Zhanghe Z, Haimin C, Xiaojun Y. Wei W, et al. Int Immunopharmacol. 2016 Oct;39:218-228. doi: 10.1016/j.intimp.2016.07.031. Epub 2016 Aug 3. Int Immunopharmacol. 2016. PMID: 27494685
BACKGROUND: As a sulfated polysaccharide, carrageenan has been widely used as common food additive. METHODS: In the present study, we investigated the effects of kappa-carrageenan on TNBS-induced gut inflammation in mice. ...The expression of IL-2, TNF-alpha …
BACKGROUND: As a sulfated polysaccharide, carrageenan has been widely used as common food additive. METHODS: In the present study, we …
Digestive fate of dietary carrageenan: Evidence of interference with digestive proteolysis and disruption of gut epithelial function.
Fahoum L, Moscovici A, David S, Shaoul R, Rozen G, Meyron-Holtz EG, Lesmes U. Fahoum L, et al. Mol Nutr Food Res. 2017 Mar;61(3). doi: 10.1002/mnfr.201600545. Epub 2017 Jan 25. Mol Nutr Food Res. 2017. PMID: 27718308
SCOPE: The objective of this study was to interrogate two mechanisms by which commercial Carrageenans (E407) (CGN) may adversely affect human health: (i) Through modification of gastric proteolysis and (ii) Through affecting gut epithelial structure and function. .. …
SCOPE: The objective of this study was to interrogate two mechanisms by which commercial Carrageenans (E407) (CGN) may adversely affe …
Effect of orally administered food-grade carrageenans on antibody-mediated and cell-mediated immunity in the inbred rat.
Nicklin S, Miller K. Nicklin S, et al. Food Chem Toxicol. 1984 Aug;22(8):615-21. doi: 10.1016/0278-6915(84)90270-9. Food Chem Toxicol. 1984. PMID: 6381264
This apparently occurred via an intact mucosa in the absence of inflammatory or pathological lesions. The carrageenan was demonstrated in macrophage-like cells present within the villi and lamina propria of the small intestine. ...However, when sheep red bloo …
This apparently occurred via an intact mucosa in the absence of inflammatory or pathological lesions. The carrageenan was demo …
Pro-inflammatory NF-kappaB and early growth response gene 1 regulate epithelial barrier disruption by food additive carrageenan in human intestinal epithelial cells.
Choi HJ, Kim J, Park SH, Do KH, Yang H, Moon Y. Choi HJ, et al. Toxicol Lett. 2012 Jun 20;211(3):289-95. doi: 10.1016/j.toxlet.2012.04.012. Epub 2012 Apr 26. Toxicol Lett. 2012. PMID: 22561171
The widely used food additive carrageenan (CGN) has been shown to induce intestinal inflammation, ulcerative colitis-like symptoms, or neoplasm in the gut epithelia in animal models, which are also clinical features of human inflammatory bowel disease. ...
The widely used food additive carrageenan (CGN) has been shown to induce intestinal inflammation, ulcerative colitis-like symptoms, o …
Intestinal transport of some macromolecules in food.
Weiner ML. Weiner ML. Food Chem Toxicol. 1988 Oct;26(10):867-80. doi: 10.1016/0278-6915(88)90028-2. Food Chem Toxicol. 1988. PMID: 3065162 Review.
It will be shown that macromolecules can be transported across this barrier by endocytosis; by uptake into the gut-associated lymphoid tissue, and possibly by uptake into the goblet cells. It is considered highly unlikely that large micron-sized particles pass betwe …
It will be shown that macromolecules can be transported across this barrier by endocytosis; by uptake into the gut-associated lymphoi …
Development of the early mucosal lesions in experimental inflammatory bowel disease--implications for pathogenesis.
Moyana TN, Xiang J, Qi Y, Kalra J. Moyana TN, et al. Exp Mol Pathol. 1994 Apr;60(2):119-29. doi: 10.1006/exmp.1994.1011. Exp Mol Pathol. 1994. PMID: 8070540
Light microscopy showed an increased amount of inflammatory cells in the gut wall with prominent Peyer's patches, microgranulomas, crypt abscesses, pin-point ulcerations, and a repair reaction. Scanning electron microscopy revealed pin-point ulcerations in re …
Light microscopy showed an increased amount of inflammatory cells in the gut wall with prominent Peyer's patches, micro …
Local and systemic immune responses to intestinally presented antigen.
Nicklin S, Miller K. Nicklin S, et al. Int Arch Allergy Appl Immunol. 1983;72(1):87-90. doi: 10.1159/000234846. Int Arch Allergy Appl Immunol. 1983. PMID: 6874102
We have investigated the ability of the gut-associated lymphoid tissues (GALT) to react against standard antigens presented via different routes of administration. ...These results indicate that GALT is capable of reacting to foreign materials penetrating the gut wa …
We have investigated the ability of the gut-associated lymphoid tissues (GALT) to react against standard antigens presented via diffe …