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767 results

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Page 1
Caryophyllene Oxide Induces Ferritinophagy by Regulating the NCOA4/FTH1/LC3 Pathway in Hepatocellular Carcinoma.
Xiu Z, Zhu Y, Han J, Li Y, Yang X, Yang G, Song G, Li S, Li Y, Cheng C, Li Y, Fang J, Li X, Jin N. Xiu Z, et al. Front Pharmacol. 2022 Jul 11;13:930958. doi: 10.3389/fphar.2022.930958. eCollection 2022. Front Pharmacol. 2022. PMID: 35899120 Free PMC article.
NCOA4, FTH1, and LC3 were found to be targeted regulators of caryophyllene oxide. Caryophyllene oxide regulated NCOA4, LC3 , and FTH1 to promote ferritinophagy. ...In conclusion, caryophyllene oxide may be used as a ferritinophagy activat …
NCOA4, FTH1, and LC3 were found to be targeted regulators of caryophyllene oxide. Caryophyllene oxide regulated …
beta-caryophyllene and beta-caryophyllene oxide-natural compounds of anticancer and analgesic properties.
Fidyt K, Fiedorowicz A, Strządała L, Szumny A. Fidyt K, et al. Cancer Med. 2016 Oct;5(10):3007-3017. doi: 10.1002/cam4.816. Epub 2016 Sep 30. Cancer Med. 2016. PMID: 27696789 Free PMC article. Review.
Natural bicyclic sesquiterpenes, beta-caryophyllene (BCP) and beta-caryophyllene oxide (BCPO), are present in a large number of plants worldwide. ...
Natural bicyclic sesquiterpenes, beta-caryophyllene (BCP) and beta-caryophyllene oxide (BCPO), are present in a large number o …
Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.
Russo EB. Russo EB. Br J Pharmacol. 2011 Aug;163(7):1344-64. doi: 10.1111/j.1476-5381.2011.01238.x. Br J Pharmacol. 2011. PMID: 21749363 Free PMC article. Review.
This review will explore another echelon of phytotherapeutic agents, the cannabis terpenoids: limonene, myrcene, alpha-pinene, linalool, beta-caryophyllene, caryophyllene oxide, nerolidol and phytol. Terpenoids share a precursor with phytocannabinoids, and are all f …
This review will explore another echelon of phytotherapeutic agents, the cannabis terpenoids: limonene, myrcene, alpha-pinene, linalool, bet …
beta-Caryophyllene oxide inhibits metastasis by downregulating MMP-2, p-p38 and p-ERK in human fibrosarcoma cells.
Jo HW, Kim MM. Jo HW, et al. J Food Biochem. 2022 Dec;46(12):e14468. doi: 10.1111/jfbc.14468. Epub 2022 Oct 3. J Food Biochem. 2022. PMID: 36190169
Matrix metalloproteinases (MMPs) allow tumor cells to move into surrounding tissues in many malignancies, but metastasis is blocked by MMPs inhibitors. Therefore, the effect of beta-caryophyllene oxide (CPO) contained in Piper nigrum on Mitogen-activated protein kin …
Matrix metalloproteinases (MMPs) allow tumor cells to move into surrounding tissues in many malignancies, but metastasis is blocked by MMPs …
beta-caryophyllene oxide induces apoptosis and inhibits proliferation of A549 lung cancer cells.
Shabana SM, Gad NS, Othman AI, Mohamed AF, El-Missiry MA. Shabana SM, et al. Med Oncol. 2023 May 26;40(7):189. doi: 10.1007/s12032-023-02022-9. Med Oncol. 2023. PMID: 37233859 Free PMC article.
There is new hope in the fight against lung cancer thanks to the chemopreventive properties of natural dietary substances like beta-caryophyllene oxide (CPO), and research is currently being done to test this theory. ...
There is new hope in the fight against lung cancer thanks to the chemopreventive properties of natural dietary substances like beta-caryo
Caryophyllene Oxide, the Active Compound Isolated from Leaves of Hymenaea courbaril L. (Fabaceae) with Antiproliferative and Apoptotic Effects on PC-3 Androgen-Independent Prostate Cancer Cell Line.
Delgado C, Mendez-Callejas G, Celis C. Delgado C, et al. Molecules. 2021 Oct 12;26(20):6142. doi: 10.3390/molecules26206142. Molecules. 2021. PMID: 34684723 Free PMC article.
The most cytotoxic fraction was analyzed by GC/MS to identify the active compounds. The majority compound, caryophyllene oxide, induced early and late apoptosis, depolarized the mitochondrial membrane, leading to several morphological changes and shifts in apoptotic …
The most cytotoxic fraction was analyzed by GC/MS to identify the active compounds. The majority compound, caryophyllene oxide
Stimulation of Hemolysis and Eryptosis by beta-Caryophyllene Oxide.
Alghareeb SA, Alfhili MA, Alsughayyir J. Alghareeb SA, et al. Life (Basel). 2023 Dec 4;13(12):2299. doi: 10.3390/life13122299. Life (Basel). 2023. PMID: 38137900 Free PMC article.
BACKGROUND: Eryptosis stimulated by anticancer drugs can lead to anemia in patients. beta-caryophyllene oxide (CPO) is an anticancer sesquiterpene present in various plants; however, its effect on the structure and function of human red blood cells (RBCs) remains un …
BACKGROUND: Eryptosis stimulated by anticancer drugs can lead to anemia in patients. beta-caryophyllene oxide (CPO) is an anti …
Excito-repellent activity of beta-caryophyllene oxide against Aedes aegypti and Anopheles minimus.
Nararak J, Sathantriphop S, Kongmee M, Mahiou-Leddet V, Ollivier E, Manguin S, Chareonviriyaphap T. Nararak J, et al. Acta Trop. 2019 Sep;197:105030. doi: 10.1016/j.actatropica.2019.05.021. Epub 2019 May 20. Acta Trop. 2019. PMID: 31121148
Contact irritant and non-contact repellent activities of beta-caryophyllene oxide were evaluated against laboratory strains of female Aedes aegypti (USDA strain), a major arbovirus vector and Anopheles minimus (KU strain), a major malaria parasite vector, compared w …
Contact irritant and non-contact repellent activities of beta-caryophyllene oxide were evaluated against laboratory strains of …
Antinociceptive, anti-inflammatory, and cytotoxic properties of Origanum vulgare essential oil, rich with beta-caryophyllene and beta-caryophyllene oxide.
Moghrovyan A, Parseghyan L, Sevoyan G, Darbinyan A, Sahakyan N, Gaboyan M, Karabekian Z, Voskanyan A. Moghrovyan A, et al. Korean J Pain. 2022 Apr 1;35(2):140-151. doi: 10.3344/kjp.2022.35.2.140. Korean J Pain. 2022. PMID: 35354677 Free PMC article.
RESULTS: The maximal content of beta-caryophyllene and beta-caryophyllene oxide in OVA essential oil was revealed in the period of blossoming (8.18% and 13.36%, correspondently). ...
RESULTS: The maximal content of beta-caryophyllene and beta-caryophyllene oxide in OVA essential oil was revealed in the perio …
Beta caryophyllene and caryophyllene oxide, isolated from Aegle marmelos, as the potent anti-inflammatory agents against lymphoma and neuroblastoma cells.
Sain S, Naoghare PK, Devi SS, Daiwile A, Krishnamurthi K, Arrigo P, Chakrabarti T. Sain S, et al. Antiinflamm Antiallergy Agents Med Chem. 2014 Mar;13(1):45-55. doi: 10.2174/18715230113129990016. Antiinflamm Antiallergy Agents Med Chem. 2014. PMID: 24484210
Furthermore, in-silico approach was employed to understand the upstream target involved in the induction of apoptosis by the beta caryophyllene and caryophyllene oxide fractions of Aegle marmelos extract. Herein, we report that beta caryophyllene and caryophyllen
Furthermore, in-silico approach was employed to understand the upstream target involved in the induction of apoptosis by the beta caryophyll …
767 results