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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1976 1
1977 3
1978 8
1979 8
1980 12
1981 10
1982 13
1983 14
1984 14
1985 13
1986 9
1987 22
1988 12
1989 18
1990 23
1991 13
1992 10
1993 12
1994 10
1995 11
1996 7
1997 9
1998 9
1999 12
2000 12
2001 4
2002 10
2003 10
2004 7
2005 11
2006 6
2007 7
2008 7
2009 6
2010 8
2011 10
2012 9
2013 16
2014 13
2015 13
2016 11
2017 12
2018 14
2019 14
2020 14
2021 14
2022 10
2023 11
2024 16
2025 18
2026 7

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533 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia.
Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Group; Lee TC, Barina LA, Walls G, Goodman AL, Yahav D, Cheng MP, Bonten M, Bowen AC, Boyles T, Daneman N, Ekkelenkamp MB, Ghanem-Zoubi N, Hensgens MPM, Jager NGL, Kaasch AJ, Kouijzer IJE, Lewis RJ, Lumley T, Lye DC, McDonald EG, McKew G, McLean ARD, McMullan BJ, McQuilten ZK, Morpeth SC, Paterson DL, Roberts JA, Robinson JO, Saito H, Scarborough M, Ten Oever J, Turner RM, Tverring J, van Hal SJ, Webb SA, Whiteway LM, Arias CA, Henderson A, Heriot GS, Snelling TL, Afra K, Ali SS, Amit S, Anagnostou NA, Archuleta S, Aston SJ, Athan E, Baharav N, Bai AD, Barber BE, Baskaran A, Berkeley MMA, Best EJ, Bhilave NR, Bloomfield MG, Bond KA, Bostock J, Botheras CL, Boyd MA, Bradshaw SME, Briggs EJ, Britton PN, Campbell AJ, Carr BZ, Chancellor JA, Chen K, Cheong EY, Chew KL, Chia PY, Chomba R, Chong BSW, Clews CJN, Cohen JM, Commons RJ, Cutfield T, Daley P, Daniel DS, Davies J, De P, Denholm JT, Di Virgilio M, Dishon-Benattar Y, Dotel R, Duan EH, Easom N, Eliakim-Raz N, England MM, Fahmy M, Findlater AR, Flanagan KL, Foo EZJ, Foo H, Forster DP, Fralick M, Frazer JL, Gador-Whyte AP, Garnham K, German GJ, Ghosh N, Gisolf EH, Giulier… See abstract for full author list ➔ Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Group, et al. N Engl J Med. 2026 Jun 18;394(23):2329-2339. doi: 10.1056/NEJMoa2506905. N Engl J Med. 2026. PMID: 42308484 Free PMC article. Clinical Trial.
BACKGROUND: Staphylococcus aureus bacteremia is associated with high mortality. Whether cefazolin or an antistaphylococcal penicillin should be preferred for the treatment of methicillin-susceptible S. aureus bacteremia is unclear. ...CONCLUSIONS: In patients with methicil …
BACKGROUND: Staphylococcus aureus bacteremia is associated with high mortality. Whether cefazolin or an antistaphylococcal penicillin …
Cloxacillin versus cefazolin for meticillin-susceptible Staphylococcus aureus bacteraemia (CloCeBa): a prospective, open-label, multicentre, non-inferiority, randomised clinical trial.
Burdet C, Saïdani N, Dupieux C, Lemaignen A, Canouï E, Surgers L, Vareil MO, Lefort A, Lepeule R, Peiffer-Smadja N, Charmillon A, Le Moing V, Boutoille D, Tolsma V, Abgrall S, Wolff M, Tattevin P, Esposito-Farèse M, Vandenesch F, Duval X, Tubiana S, Lescure FX; CloCeBa Study Group. Burdet C, et al. Lancet. 2025 Nov 15;406(10517):2349-2359. doi: 10.1016/S0140-6736(25)01624-1. Epub 2025 Oct 17. Lancet. 2025. PMID: 41115439 Free article. Clinical Trial.
FINDINGS: Between Sept 5, 2018, and Nov 16, 2023, 315 participants were enrolled and assigned to cefazolin (n=158) or cloxacillin (n=157); 12 participants were excluded from analysis in the cefazolin group, and 11 in the cloxacillin group (final population of 146 in …
FINDINGS: Between Sept 5, 2018, and Nov 16, 2023, 315 participants were enrolled and assigned to cefazolin (n=158) or cloxacillin (n= …
Cefazolin vs. antistaphylococcal penicillins for the treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a systematic review and meta-analysis.
Prosty C, Noutsios D, Lee TC, Daneman N, Davis JS, Jager NGL, Ghanem-Zoubi N, Goodman AL, Kaasch AJ, Kouijzer I, McMullan BJ, McDonald EG, Tong SYC, Ong SWX; Staphylococcus aureus Network Adaptive Platform MSSA/PSSA domain specific working group. Prosty C, et al. Clin Microbiol Infect. 2025 Aug;31(8):1272-1282. doi: 10.1016/j.cmi.2025.04.045. Epub 2025 May 9. Clin Microbiol Infect. 2025. PMID: 40349971 Free article.
BACKGROUND: There is debate on whether cefazolin or antistaphylococcal penicillins should be the first-line treatment for methicillin-susceptible Staphylococcus aureus (MSSA) bacteraemia. ...OBJECTIVES: We conducted a systematic review and meta-analysis comparing cefazo …
BACKGROUND: There is debate on whether cefazolin or antistaphylococcal penicillins should be the first-line treatment for methicillin …
Assessment of the Frequency of Dual Allergy to Penicillins and Cefazolin: A Systematic Review and Meta-analysis.
Sousa-Pinto B, Blumenthal KG, Courtney L, Mancini CM, Jeffres MN. Sousa-Pinto B, et al. JAMA Surg. 2021 Apr 1;156(4):e210021. doi: 10.1001/jamasurg.2021.0021. Epub 2021 Apr 14. JAMA Surg. 2021. PMID: 33729459 Free PMC article.
IMPORTANCE: Cefazolin is the preoperative antibiotic of choice because it is safer and more efficacious than second-line alternatives. ...The frequency of penicillin allergy was 4.4% (95% CrI, 0%-23.0%; I2 = 75%) for the 8 studies that exclusively assessed surgical patient …
IMPORTANCE: Cefazolin is the preoperative antibiotic of choice because it is safer and more efficacious than second-line alternatives …
Cefazolin versus anti-staphylococcal penicillins for the treatment of patients with Staphylococcus aureus bacteraemia.
Weis S, Kesselmeier M, Davis JS, Morris AM, Lee S, Scherag A, Hagel S, Pletz MW. Weis S, et al. Clin Microbiol Infect. 2019 Jul;25(7):818-827. doi: 10.1016/j.cmi.2019.03.010. Epub 2019 Mar 27. Clin Microbiol Infect. 2019. PMID: 30928559 Free article.
BACKGROUND: For patients with bacteraemia caused by methicillin-sensitive Staphylococcus aureus anti-staphylococcal penicillins (ASPs) or cefazolin are agents of choice. While ASPs are potentially nephrotoxic, cefazolin may be less effective in some S. aureus strain …
BACKGROUND: For patients with bacteraemia caused by methicillin-sensitive Staphylococcus aureus anti-staphylococcal penicillins (ASPs) or …
Trial of Vancomycin and Cefazolin as Surgical Prophylaxis in Arthroplasty.
Peel TN, Astbury S, Cheng AC, Paterson DL, Buising KL, Spelman T, Tran-Duy A, Adie S, Boyce G, McDougall C, Molnar R, Mulford J, Rehfisch P, Solomon M, Crawford R, Harris-Brown T, Roney J, Wisniewski J, de Steiger R; ASAP Trial Group. Peel TN, et al. N Engl J Med. 2023 Oct 19;389(16):1488-1498. doi: 10.1056/NEJMoa2301401. N Engl J Med. 2023. PMID: 37851875 Clinical Trial.
METHODS: In this multicenter, double-blind, superiority, placebo-controlled trial, we randomly assigned adult patients without known methicillin-resistant Staphylococcus aureus (MRSA) colonization who were undergoing arthroplasty to receive 1.5 g of vancomycin or normal saline pl …
METHODS: In this multicenter, double-blind, superiority, placebo-controlled trial, we randomly assigned adult patients without known methici …
Cefazolin vs. anti-staphylococcal penicillins for treatment of methicillin-susceptible Staphylococcus aureus bloodstream infections in acutely ill adult patients: Results of a systematic review and meta-analysis.
Lee BJ, Wang SK, Constantino-Corpuz JK, Apolinario K, Nadler B, McDanel JS, Scheetz MH, Rhodes NJ. Lee BJ, et al. Int J Antimicrob Agents. 2019 Mar;53(3):225-233. doi: 10.1016/j.ijantimicag.2018.11.013. Epub 2018 Nov 23. Int J Antimicrob Agents. 2019. PMID: 30476572
A systematic literature review and meta-analysis was conducted to evaluate the comparative efficacy and tolerability of cefazolin vs. anti-staphylococcal penicillins (ASPs) for methicillin-susceptible Staphylococcus aureus (MSSA) bloodstream infections (BSI). ...The role o …
A systematic literature review and meta-analysis was conducted to evaluate the comparative efficacy and tolerability of cefazolin vs. …
Cefazolin as surgical antimicrobial prophylaxis in hysterectomy: A systematic review and meta-analysis of randomized controlled trials.
Pop-Vicas A, Johnson S, Safdar N. Pop-Vicas A, et al. Infect Control Hosp Epidemiol. 2019 Feb;40(2):142-149. doi: 10.1017/ice.2018.286. Epub 2018 Dec 5. Infect Control Hosp Epidemiol. 2019. PMID: 30516122
OBJECTIVE: Current practice guidelines recommend cefazolin, cefoxitin, cefotetan, or ampicillin-sulbactam as first-line antibiotic prophylaxis in hysterectomy. ...We excluded trials of beta-lactams no longer in clinical use. RESULTS: In terms of SSI incidence, cefazolin …
OBJECTIVE: Current practice guidelines recommend cefazolin, cefoxitin, cefotetan, or ampicillin-sulbactam as first-line antibiotic pr …
Comparing prophylactic use of cefazolin for SSI in cesarean section: a systematic review and meta-analysis.
Li M, Shi B, Ma J, Peng X, Shi J. Li M, et al. Arch Gynecol Obstet. 2021 Feb;303(2):313-320. doi: 10.1007/s00404-020-05873-z. Epub 2020 Nov 26. Arch Gynecol Obstet. 2021. PMID: 33242142
English search words: Cesarean section, Surgical site infection, Cefazolin. The majority of the literature are randomized controlled trials comparing varied regimens of cefazolin. ...For pregnant women with different risk factors, cefazolin alone or the type, …
English search words: Cesarean section, Surgical site infection, Cefazolin. The majority of the literature are randomized controlled …
Cefazolin susceptibility of coagulase-negative staphylococci (CoNS) causing late-onset neonatal bacteraemia.
Marr I, Swe K, Henderson A, Lacey JA, Carter GP, Ferguson JK. Marr I, et al. J Antimicrob Chemother. 2022 Feb 2;77(2):338-344. doi: 10.1093/jac/dkab402. J Antimicrob Chemother. 2022. PMID: 34791307 Free article. Clinical Trial.
CONCLUSIONS: CoNS displayed distinctly lower MIC values of cefazolin than of other agents tested. MIC variation may be related to binding affinity of PBP2a or regulation of expression of mecA by mecR1-mecI functional genes. ...It is considered justified to conduct a random …
CONCLUSIONS: CoNS displayed distinctly lower MIC values of cefazolin than of other agents tested. MIC variation may be related to bin …
533 results