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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1897 1
1906 1
1908 1
1914 1
1915 1
1916 2
1925 1
1927 1
1928 1
1929 2
1930 1
1931 1
1933 1
1934 1
1936 1
1938 1
1939 1
1941 2
1945 16
1946 57
1947 84
1948 68
1949 70
1950 127
1951 160
1952 170
1953 189
1954 181
1955 219
1956 208
1957 245
1958 231
1959 255
1960 319
1961 312
1962 333
1963 466
1964 683
1965 572
1966 650
1967 947
1968 1205
1969 1080
1970 1249
1971 1595
1972 1848
1973 1853
1974 2020
1975 2325
1976 2341
1977 2354
1978 2556
1979 2663
1980 2774
1981 2893
1982 3440
1983 3772
1984 3927
1985 4517
1986 4792
1987 5160
1988 6026
1989 6992
1990 7446
1991 7569
1992 7245
1993 7376
1994 7851
1995 8286
1996 8340
1997 8876
1998 9112
1999 9352
2000 10074
2001 10754
2002 11636
2003 12243
2004 13621
2005 14807
2006 15810
2007 16877
2008 17817
2009 18775
2010 20651
2011 22017
2012 23451
2013 24781
2014 24848
2015 25658
2016 25717
2017 25731
2018 26111
2019 26185
2020 27013
2021 27439
2022 23215
2023 21848
2024 23752
2025 25975
2026 16292

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650,511 results

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Page 1
In Vivo CD4(+) T Cell Differentiation and Function: Revisiting the Th1/Th2 Paradigm.
Ruterbusch M, Pruner KB, Shehata L, Pepper M. Ruterbusch M, et al. Annu Rev Immunol. 2020 Apr 26;38:705-725. doi: 10.1146/annurev-immunol-103019-085803. Annu Rev Immunol. 2020. PMID: 32340571 Review.
The discovery of CD4(+) T cell subset-defining master transcription factors and framing of the Th1/Th2 paradigm ignited the CD4(+) T cell field. Advances in in vivo experimental systems, however, have revealed that more complex lineage-defining transcriptional netwo …
The discovery of CD4(+) T cell subset-defining master transcription factors and framing of the Th1/Th2 paradigm ignited the CD4(+) T …
Modulating cell differentiation in cancer models.
Fulghieri P, Stivala LA, Sottile V. Fulghieri P, et al. Biochem Soc Trans. 2021 Aug 27;49(4):1803-1816. doi: 10.1042/BST20210230. Biochem Soc Trans. 2021. PMID: 34436513 Review.
Since these malignant stem cells are largely undifferentiated, inducing their lineage commitment has been proposed as a potential intervention strategy to deplete tumours from their most resistant components. Pro-differentiation approaches have thus far yielded clinical su …
Since these malignant stem cells are largely undifferentiated, inducing their lineage commitment has been proposed as a potential interventi …
Peptide Regulation of Cell Differentiation.
Khavinson V, Linkova N, Diatlova A, Trofimova S. Khavinson V, et al. Stem Cell Rev Rep. 2020 Feb;16(1):118-125. doi: 10.1007/s12015-019-09938-8. Stem Cell Rev Rep. 2020. PMID: 31808038 Review.
Short peptides are molecules with small molecular weight, capable of penetrating the cell membrane and nuclear membrane for epigenetic regulation of gene expression, including the genes responsible for cell differentiation. ...Research in the area of directed …
Short peptides are molecules with small molecular weight, capable of penetrating the cell membrane and nuclear membrane for epigeneti …
Cell differentiation.
Bennett V. Bennett V. Curr Opin Cell Biol. 2008 Dec;20(6):607-8. doi: 10.1016/j.ceb.2008.10.006. Epub 2008 Nov 18. Curr Opin Cell Biol. 2008. PMID: 18973808 No abstract available.
Programmed T cell differentiation: Implications for transplantation.
Crepeau RL, Ford ML. Crepeau RL, et al. Cell Immunol. 2020 May;351:104099. doi: 10.1016/j.cellimm.2020.104099. Epub 2020 Mar 29. Cell Immunol. 2020. PMID: 32247511 Free PMC article. Review.
While T cells play a critical role in protective immunity against infection, they are also responsible for graft rejection in the setting of transplantation. T cell differentiation is regulated by both intrinsic transcriptional pathways as well as extrinsic factors …
While T cells play a critical role in protective immunity against infection, they are also responsible for graft rejection in the setting of …
Cell polarity: compassing cell division and differentiation in plants.
Zhang Y, Dong J. Zhang Y, et al. Curr Opin Plant Biol. 2018 Oct;45(Pt A):127-135. doi: 10.1016/j.pbi.2018.06.003. Epub 2018 Jun 27. Curr Opin Plant Biol. 2018. PMID: 29957569 Free PMC article. Review.
Protein polarization underlies directional cell growth, cell morphogenesis, cell division, fate specification and differentiation in plant development. ...Differentiation of specialized cell types is often associated with the spatial regu …
Protein polarization underlies directional cell growth, cell morphogenesis, cell division, fate specification and di …
Metabolic dynamics instruct CD8(+) T-cell differentiation and functions.
Bevilacqua A, Li Z, Ho PC. Bevilacqua A, et al. Eur J Immunol. 2022 Apr;52(4):541-549. doi: 10.1002/eji.202149486. Epub 2022 Mar 16. Eur J Immunol. 2022. PMID: 35253907 Free PMC article. Review.
However, it has also been recently appreciated that this metabolic reprogramming also directly supports T-cell lineage differentiation. Accordingly, metabolic deficiencies and prolonged stress exposure can impact T-cell differentiation and skew them in …
However, it has also been recently appreciated that this metabolic reprogramming also directly supports T-cell lineage differentia …
Single-cell transcriptional uncertainty landscape of cell differentiation.
Gao NP, Gandrillon O, Páldi A, Herbach U, Gunawan R. Gao NP, et al. F1000Res. 2023 Jul 20;12:426. doi: 10.12688/f1000research.131861.2. eCollection 2023. F1000Res. 2023. PMID: 37545651 Free PMC article.
Conclusions: Our findings suggest a possible universal mechanism during the cell differentiation process, in which stem cells engage stochastic exploratory dynamics of gene expression at the start of the cell differentiation by increasing gene transcri …
Conclusions: Our findings suggest a possible universal mechanism during the cell differentiation process, in which stem cells …
Mechanical Properties of Materials for Stem Cell Differentiation.
Han SB, Kim JK, Lee G, Kim DH. Han SB, et al. Adv Biosyst. 2020 Nov;4(11):e2000247. doi: 10.1002/adbi.202000247. Epub 2020 Oct 9. Adv Biosyst. 2020. PMID: 33035411 Review.
Recent findings about cell fate change induced by physical stimuli have expedited the discovery of underlying regulatory mechanisms that determine stem cell differentiation. ...This progress report addresses essential biophysical regulation and alteration of …
Recent findings about cell fate change induced by physical stimuli have expedited the discovery of underlying regulatory mechanisms t …
Criticality in cell differentiation.
Bose I, Pal M. Bose I, et al. J Biosci. 2017 Dec;42(4):683-693. doi: 10.1007/s12038-017-9721-6. J Biosci. 2017. PMID: 29229886 Review.
Cell differentiation is an important process in living organisms. Differentiation is mostly based on binary decisions with the progenitor cells choosing between two specific lineages. ...In this review, an elementary introduction is given to the concept of cr …
Cell differentiation is an important process in living organisms. Differentiation is mostly based on binary decisions w …
650,511 results
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