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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1912 1
1914 1
1923 1
1930 1
1932 1
1939 1
1946 1
1951 1
1952 1
1959 4
1962 2
1963 1
1964 2
1965 1
1967 4
1968 3
1969 3
1970 5
1971 11
1972 6
1973 13
1974 9
1975 27
1976 26
1977 16
1978 13
1979 22
1980 22
1981 32
1982 49
1983 50
1984 44
1985 61
1986 48
1987 74
1988 60
1989 94
1990 99
1991 115
1992 133
1993 125
1994 169
1995 208
1996 211
1997 287
1998 267
1999 281
2000 339
2001 365
2002 397
2003 424
2004 432
2005 568
2006 609
2007 649
2008 729
2009 783
2010 888
2011 913
2012 969
2013 1078
2014 1134
2015 1099
2016 1177
2017 1136
2018 1118
2019 1107
2020 1248
2021 1272
2022 1230
2023 1208
2024 1216
2025 1449
2026 1178

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25,036 results

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Page 1
Cell fate specification and differentiation in the adult mammalian intestine.
Beumer J, Clevers H. Beumer J, et al. Nat Rev Mol Cell Biol. 2021 Jan;22(1):39-53. doi: 10.1038/s41580-020-0278-0. Epub 2020 Sep 21. Nat Rev Mol Cell Biol. 2021. PMID: 32958874 Review.
New approaches such as single-cell transcriptomics and the use of organoid models have led to the identification of the signals that guide fate specification of stem cell progeny into the six intestinal cell lineages. ...These new insights into …
New approaches such as single-cell transcriptomics and the use of organoid models have led to the identification of the signals that …
Hermaphrodite cell-fate specification.
Herman MA. Herman MA. WormBook. 2006 Jan 9:1-16. doi: 10.1895/wormbook.1.39.1. WormBook. 2006. PMID: 18050480 Free PMC article. Review.
Both cell lineage-based and cell-signaling mechanisms of cell fate specification will be discussed. Only two direct targets of the sex determination pathway that influence cell fate specification to produce hermaphrodite- …
Both cell lineage-based and cell-signaling mechanisms of cell fate specification will be discussed. Only …
Cell fate specification in the mammalian telencephalon.
Guillemot F. Guillemot F. Prog Neurobiol. 2007 Sep;83(1):37-52. doi: 10.1016/j.pneurobio.2007.02.009. Epub 2007 Mar 7. Prog Neurobiol. 2007. PMID: 17517461 Review.
I first consider the multiple extracellular signals that have been implicated in neural fate specification. Their roles are often complex, with the same signals having different effects at different developmental stages, and different signaling pathways interacting …
I first consider the multiple extracellular signals that have been implicated in neural fate specification. Their roles are of …
Photoreceptor cell fate specification in vertebrates.
Brzezinski JA, Reh TA. Brzezinski JA, et al. Development. 2015 Oct 1;142(19):3263-73. doi: 10.1242/dev.127043. Development. 2015. PMID: 26443631 Free PMC article. Review.
Photoreceptors--the light-sensitive cells in the vertebrate retina--have been extremely well-characterized with regards to their biochemistry, cell biology and physiology. ...In this Review, we outline the signaling and transcription factors that drive vertebrate ph …
Photoreceptors--the light-sensitive cells in the vertebrate retina--have been extremely well-characterized with regards to their bioc …
Cell fate specification and differentiation in the nervous system of Caenorhabditis elegans.
Sengupta P, Bargmann CI. Sengupta P, et al. Dev Genet. 1996;18(1):73-80. doi: 10.1002/(SICI)1520-6408(1996)18:1<73::AID-DVG8>3.0.CO;2-Z. Dev Genet. 1996. PMID: 8742836 Review.
Neuronal cell fates are specified by a hierarchy of events mediated by cell-intrinsic determinants and cell-cell interactions. The determination of cell fate can be subdivided into three general steps. First, cell fate is re …
Neuronal cell fates are specified by a hierarchy of events mediated by cell-intrinsic determinants and cell-cell …
At the Crossroads of Fate-Somatic Cell Lineage Specification in the Fetal Gonad.
Rotgers E, Jørgensen A, Yao HH. Rotgers E, et al. Endocr Rev. 2018 Oct 1;39(5):739-759. doi: 10.1210/er.2018-00010. Endocr Rev. 2018. PMID: 29771299 Free PMC article. Review.
After separation of the adrenal and gonadal primordia, the gonadal somatic cells initiate sex-specific differentiation during gonadal sex determination with the specification of the supporting cell lineages: Sertoli cells in the testis vs granul …
After separation of the adrenal and gonadal primordia, the gonadal somatic cells initiate sex-specific differentiation during …
Cell fate specification in the inner ear.
Fekete DM. Fekete DM. Curr Opin Neurobiol. 1996 Aug;6(4):533-41. doi: 10.1016/s0959-4388(96)80061-4. Curr Opin Neurobiol. 1996. PMID: 8794105 Review.
From its origin as a single ectodermal patch, the inner ear becomes a labyrinth of chambers housing six to eight sensory organs. Along the way, specific cell fates are realized. The secrets underlying these cell fate specifications are beginning …
From its origin as a single ectodermal patch, the inner ear becomes a labyrinth of chambers housing six to eight sensory organs. Along the w …
Pre-Meiotic Anther Development: Cell Fate Specification and Differentiation.
Walbot V, Egger RL. Walbot V, et al. Annu Rev Plant Biol. 2016 Apr 29;67:365-95. doi: 10.1146/annurev-arplant-043015-111804. Epub 2016 Jan 6. Annu Rev Plant Biol. 2016. PMID: 26735065 Review.
Research into anther ontogeny has been an active and developing field, transitioning from a strictly lineage-based view of cellular differentiation events to a more complex understanding of cell fate specification. Here we describe the modern interpretation o …
Research into anther ontogeny has been an active and developing field, transitioning from a strictly lineage-based view of cellular differen …
Minireview: pioneer transcription factors in cell fate specification.
Drouin J. Drouin J. Mol Endocrinol. 2014 Jul;28(7):989-98. doi: 10.1210/me.2014-1084. Epub 2014 May 13. Mol Endocrinol. 2014. PMID: 24825399 Free PMC article. Review.
The specification of cell fate is critical for proper cell differentiation and organogenesis. ...Although the model that emerged from these 2 decades is one in which a specific combination of TFs drives a unique cell specification …
The specification of cell fate is critical for proper cell differentiation and organogenesis. ...Although the mo …
Single-cell multiomic analysis identifies macrophage subpopulations in promoting cardiac repair.
Fu M, Jia S, Xu L, Li X, Lv Y, Zhong Y, Ai S. Fu M, et al. J Clin Invest. 2024 Aug 27;134(19):e175297. doi: 10.1172/JCI175297. J Clin Invest. 2024. PMID: 39190625 Free PMC article.
However, the function of specific MPC subtypes and the related cell fate commitment mechanisms remain elusive in regenerative and nonregenerative hearts due to their cellular heterogeneities. ...Moreover, blocking chemokine CXCR2 to inhibit the specificati …
However, the function of specific MPC subtypes and the related cell fate commitment mechanisms remain elusive in regene …
25,036 results
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