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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1957 1
1958 2
1960 1
1962 1
1963 1
1964 1
1965 1
1979 2
1980 9
1981 34
1982 88
1983 84
1984 130
1985 191
1986 252
1987 339
1988 391
1989 482
1990 547
1991 542
1992 650
1993 599
1994 670
1995 672
1996 663
1997 643
1998 663
1999 639
2000 689
2001 698
2002 700
2003 677
2004 672
2005 645
2006 725
2007 707
2008 679
2009 782
2010 822
2011 852
2012 978
2013 1020
2014 1059
2015 1090
2016 1007
2017 1028
2018 1044
2019 1002
2020 1014
2021 815
2022 584
2023 496
2024 687
2025 766
2026 414

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27,495 results

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Page 1
Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells.
Ritvo PG, Klatzmann D. Ritvo PG, et al. Front Immunol. 2019 Feb 27;10:250. doi: 10.3389/fimmu.2019.00250. eCollection 2019. Front Immunol. 2019. PMID: 30873158 Free PMC article. Review.
The role of interleukin-1 in the regulation of humoral responses is poorly documented, in contrast to its role in inflammation. Recent findings suggest there is an interleukin-1 axis in the follicular T cell control of B cell responses, i …
The role of interleukin-1 in the regulation of humoral responses is poorly documented, in contrast to its role in infla …
Interleukins.
Dinarello CA, Mier JW. Dinarello CA, et al. Annu Rev Med. 1986;37:173-8. doi: 10.1146/annurev.me.37.020186.001133. Annu Rev Med. 1986. PMID: 3518604 Review.
Interleukins are polypeptides that act on leukocytes and other tissue targets. Interleukin-1, produced by macrophages and other cells, activates lymphocytes and also induces several components of the host's acute-phase response to infection and injury. …
Interleukins are polypeptides that act on leukocytes and other tissue targets. Interleukin-1, produced by macrophages and othe …
Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6-mediated gene editing in hematopoietic stem cells.
Conti A, Giannetti K, Midena F, Beretta S, Gualandi N, De Marco R, Carsana E, Varesi A, Tavella T, Alessandrini L, Zarghamian P, Weber A, Ferrari S, Brombin C, Gilioli D, Della Volpe L, Xie SZ, Merelli I, Cathomen T, Naldini L, Di Micco R. Conti A, et al. Cell Rep Med. 2025 Jun 17;6(6):102157. doi: 10.1016/j.xcrm.2025.102157. Epub 2025 Jun 3. Cell Rep Med. 2025. PMID: 40466639 Free PMC article.
However, cellular responses induced by CRISPR-Cas9/AAV6 engineering impair the long-term repopulating potential of HDR-edited HSPCs, adversely impacting the safety and efficacy of clinical translation. ...We show that transient p53 inhibition or blocking inflammator …
However, cellular responses induced by CRISPR-Cas9/AAV6 engineering impair the long-term repopulating potential of HDR-edited …
Secretion of interleukin-1 beta by a leukemia cell line in response to lipopolysaccharide and mezerein.
Gaffney EV, Stoner CR, Lingenfelter SE, Koch GA. Gaffney EV, et al. J Biol Response Mod. 1990 Apr;9(2):205-11. J Biol Response Mod. 1990. PMID: 2111375
The current investigation, however, demonstrates that THP-1 cells differ from normal monocytes in their secretion of interleukin-1 beta (IL-1 beta) following exposure to reagents that induce synthesis. ...The role of IFN gamma in stimulating IL-1 beta secreti …
The current investigation, however, demonstrates that THP-1 cells differ from normal monocytes in their secretion of interleukin …
A Guide to IL-1 family cytokines in adjuvanticity.
Muñoz-Wolf N, Lavelle EC. Muñoz-Wolf N, et al. FEBS J. 2018 Jul;285(13):2377-2401. doi: 10.1111/febs.14467. Epub 2018 May 3. FEBS J. 2018. PMID: 29656546 Free article. Review.
While tightly regulated, cytokines of the IL-1 family are normally released in response to cellular stress and in combination with other danger-/damage-associated molecular patterns (DAMPs), triggering potent local and systemic immune responses. ...The coordi …
While tightly regulated, cytokines of the IL-1 family are normally released in response to cellular stress and in combination …
Identification of major cellular proteins synthesized in response to interleukin-1 and interleukin-6 in human hepatoma HepG2 cells.
Bonar E, Dubin A, Bierczyńska-Krzysik A, Noga M, Silberring J, Stalińska K, Koj A. Bonar E, et al. Cytokine. 2006 Jan 21;33(2):111-7. doi: 10.1016/j.cyto.2005.12.011. Epub 2006 Feb 14. Cytokine. 2006. PMID: 16483792
Interleukin-1 (IL-1) and interleukin-6 (IL-6) are principal proinflammatory cytokines inducing the acute phase response of various tissues, including liver. ...The identification of three cytokine-responsive proteins was confirmed by biosynthetic label …
Interleukin-1 (IL-1) and interleukin-6 (IL-6) are principal proinflammatory cytokines inducing the acute phase response …
Effects of DMAEMA and 4-methoxyphenol on gingival fibroblast growth, metabolism, and response to interleukin-1.
Lapp CA, Schuster GS. Lapp CA, et al. J Biomed Mater Res. 2002 Apr;60(1):30-5. doi: 10.1002/jbm.10057. J Biomed Mater Res. 2002. PMID: 11835156
DMAEMA (1.6- 6.4 mM) virtually eliminated the acute IL-6 response of these cells to an interleukin-1beta challenge; only at 0.32 mM DMAEMA was the response restored. MEHQ (1.6-16 microM) reduced the IL-6 response by >50%. In summary, both growth and …
DMAEMA (1.6- 6.4 mM) virtually eliminated the acute IL-6 response of these cells to an interleukin-1beta challenge; only at 0. …
Interleukin-1 induces human bone marrow-derived fibroblasts to produce multilineage hematopoietic growth factors.
Lee M, Segal GM, Bagby GC. Lee M, et al. Exp Hematol. 1987 Oct;15(9):983-8. Exp Hematol. 1987. PMID: 3498642
Interleukin-1 (IL-1) has been shown to induce stromal cells, including endothelial cells and fibroblasts, to produce multilineage hematopoietic growth factors. ...We conclude that bone marrow fibroblasts produce hematopoietic growth factors in respo …
Interleukin-1 (IL-1) has been shown to induce stromal cells, including endothelial cells and fibroblasts, to pro …
Intracerebroventricular infusion of interleukin 1 rapidly decreases peripheral cellular immune responses.
Sundar SK, Becker KJ, Cierpial MA, Carpenter MD, Rankin LA, Fleener SL, Ritchie JC, Simson PE, Weiss JM. Sundar SK, et al. Proc Natl Acad Sci U S A. 1989 Aug;86(16):6398-402. doi: 10.1073/pnas.86.16.6398. Proc Natl Acad Sci U S A. 1989. PMID: 2548213 Free PMC article.
Low doses (50-200 pg or 3.1-12.4 fmol) of interleukin 1 (IL-1) infused into the brain of rats produced rapid suppression of various cellular immune responses in peripheral lymphocytes of rats. ...Finally, IL-1 infusion suppressed cellular immune …
Low doses (50-200 pg or 3.1-12.4 fmol) of interleukin 1 (IL-1) infused into the brain of rats produced rapid suppression of va …
Dual functionality of interleukin-1 family cytokines: implications for anti-interleukin-1 therapy.
Luheshi NM, Rothwell NJ, Brough D. Luheshi NM, et al. Br J Pharmacol. 2009 Aug;157(8):1318-29. doi: 10.1111/j.1476-5381.2009.00331.x. Br J Pharmacol. 2009. PMID: 19681864 Free PMC article. Review.
Cytokines are coordinators of inflammation and were originally defined as secreted mediators, released from expressing cells to activate plasma membrane receptors on responsive cells. However, a group of cytokines is now recognized as having dual functionalit …
Cytokines are coordinators of inflammation and were originally defined as secreted mediators, released from expressing cells to activ …
27,495 results
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