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Cardiovascular Protective Effects of Centella asiatica and Its Triterpenes: A Review.
Razali NNM, Ng CT, Fong LY. Razali NNM, et al. Planta Med. 2019 Nov;85(16):1203-1215. doi: 10.1055/a-1008-6138. Epub 2019 Sep 20. Planta Med. 2019. PMID: 31539918 Free article. Review.
Centella asiatica, a triterpene-rich medicinal herb, is traditionally used to treat various types of diseases including neurological, dermatological, and metabolic diseases. ...In addition, their beneficial effects on conditions associated with cardiovascular …
Centella asiatica, a triterpene-rich medicinal herb, is traditionally used to treat various types of diseases including neurol …
Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review.
Sun B, Wu L, Wu Y, Zhang C, Qin L, Hayashi M, Kudo M, Gao M, Liu T. Sun B, et al. Front Pharmacol. 2020 Sep 4;11:568032. doi: 10.3389/fphar.2020.568032. eCollection 2020. Front Pharmacol. 2020. PMID: 33013406 Free PMC article. Review.
Centella asiatica (also known as Centella asiatica (L.) Urb. or Gotu kola) is a traditional Chinese medicine with extensive medicinal value, which is commonly used in Southeast Asian countries. This study aimed to summarize the effects of C. asiatic …
Centella asiatica (also known as Centella asiatica (L.) Urb. or Gotu kola) is a traditional Chinese medicine wit …
Asiaticoside alleviates atherosclerosis progression by suppressing RhoF-NF-κB/MAPK signaling and inflammation in macrophages.
Wang J, Lei L, Wang S, Sun Y. Wang J, et al. Phytomedicine. 2025 Oct;146:157137. doi: 10.1016/j.phymed.2025.157137. Epub 2025 Aug 5. Phytomedicine. 2025. PMID: 40795589 Free article.
BACKGROUND: Asiaticoside (AT), a triterpenoid derived from Centella asiatica, has long been recognized for its anti-inflammatory properties. Its potential to ameliorate atherosclerosis (AS), a chronic inflammatory disease, positions it as a promising therapeutic age …
BACKGROUND: Asiaticoside (AT), a triterpenoid derived from Centella asiatica, has long been recognized for its anti-inflammato …
Centella asiatica extract improves senescence-associated metabolic dysfunction by targeting inflammation in adipose tissue and macrophage in obesity-induced insulin resistance mice.
Barinda AJ, Arozal W, Dwita NC, Safutra MS, Shimizu I, Hsiao YT, Sandora N, Hakim RW, Khatimah NG, Hardi H. Barinda AJ, et al. Front Endocrinol (Lausanne). 2025 Jul 31;16:1589444. doi: 10.3389/fendo.2025.1589444. eCollection 2025. Front Endocrinol (Lausanne). 2025. PMID: 40822955 Free PMC article.
The inflammation-mediated senescence in White Adipose Tissue (WAT) is important in obesity-induced IR. Centella asiatica (CA) is a potential medicinal plant with anti-aging and anti-obesity properties. ...
The inflammation-mediated senescence in White Adipose Tissue (WAT) is important in obesity-induced IR. Centella asiatica (CA) …
Ethnobotany, Phytochemistry and Pharmacological Features of Centella asiatica: A Comprehensive Review.
Torbati FA, Ramezani M, Dehghan R, Amiri MS, Moghadam AT, Shakour N, Elyasi S, Sahebkar A, Emami SA. Torbati FA, et al. Adv Exp Med Biol. 2021;1308:451-499. doi: 10.1007/978-3-030-64872-5_25. Adv Exp Med Biol. 2021. PMID: 33861456 Review.
Centella asiatica (CA) or Gotu cola is an herbal plant from the Apiaceae family with a long history of usage in different traditional medicines. ...Pharmacological studies revealed a wide range of beneficial effects of CA on CNS, cardiovascular, lung, liver, …
Centella asiatica (CA) or Gotu cola is an herbal plant from the Apiaceae family with a long history of usage in different trad …
Centella asiatica (L.) Urb. attenuates cardiac hypertrophy and improves heart function through multi-level mechanisms revealed by systems pharmacology.
Ding B, Niu W, Wang S, Zhang F, Wang H, Chen X, Chen S, Ma S, Kang W, Wang M, Li L, Xiao W, Guo Z, Wang Y. Ding B, et al. J Ethnopharmacol. 2022 Jun 12;291:115106. doi: 10.1016/j.jep.2022.115106. Epub 2022 Feb 15. J Ethnopharmacol. 2022. PMID: 35181485
Therefore, searching for new approaches to treat CH is urgent. Centella asiatica (L.) Urb. (CA), a traditional food and medicinal natural plant, has been turned out to be effective in the treatment of cardiovascular disease, but its efficacy and potential mec …
Therefore, searching for new approaches to treat CH is urgent. Centella asiatica (L.) Urb. (CA), a traditional food and medici …
A Clinical Trial to Evaluate the Safety and Efficacy of Centella asiatica for Ulcerative Colitis.
Guo X, Suzuki H, Sawafuji T, Fukuda S, Yamada T, Kobayashi M, Suzuki H, Akiyama S, Mathis BJ, Kawai H, Matsubara D, Tsuchiya K. Guo X, et al. JGH Open. 2025 Aug 18;9(8):e70258. doi: 10.1002/jgh3.70258. eCollection 2025 Aug. JGH Open. 2025. PMID: 40832006 Free PMC article.
AIMS: We previously reported that telomerase activator Centella asiatica (CA) can normalize the crypt structure of human colonic organoids in an ulcerative colitis (UC) model. ...
AIMS: We previously reported that telomerase activator Centella asiatica (CA) can normalize the crypt structure of human colon …
Centella asiatica (L.) Urb. Prevents Hypertension and Protects the Heart in Chronic Nitric Oxide Deficiency Rat Model.
Bunaim MK, Kamisah Y, Mohd Mustazil MN, Fadhlullah Zuhair JS, Juliana AH, Muhammad N. Bunaim MK, et al. Front Pharmacol. 2021 Dec 3;12:742562. doi: 10.3389/fphar.2021.742562. eCollection 2021. Front Pharmacol. 2021. PMID: 34925007 Free PMC article.
Centella asiatica (L.) Urb. belongs to the plant family Apiaceae (Umbelliferae). It contains a high amount of triterpenoid and flavonoid that have antioxidant properties and are involved in the renin-angiotensin-aldosterone system which is an important hormon …
Centella asiatica (L.) Urb. belongs to the plant family Apiaceae (Umbelliferae). It contains a high amount of triterpenoid and …
A review of pharmacokinetic and pharmacological properties of asiaticoside, a major active constituent of Centella asiatica (L.) Urb.
He Z, Hu Y, Niu Z, Zhong K, Liu T, Yang M, Ji L, Hu W. He Z, et al. J Ethnopharmacol. 2023 Feb 10;302(Pt A):115865. doi: 10.1016/j.jep.2022.115865. Epub 2022 Oct 25. J Ethnopharmacol. 2023. PMID: 36306932 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Centella asiatica (L.) Urb., a potential medicinal plant, is widely used in orient traditional medicine. ...The keywords used in our search included "asiaticoside", "Centella asiatica", "pharmacokinetics", "nerve", "canc …
ETHNOPHARMACOLOGICAL RELEVANCE: Centella asiatica (L.) Urb., a potential medicinal plant, is widely used in orient traditional …
Centella asiatica inhibits renal interstitial fibrosis by regulating Smad3 and Smad7 expression in the TGFbeta signaling pathway.
Zhang Z, Ma J, Feng R, Wang Z. Zhang Z, et al. Int J Clin Exp Pathol. 2018 Feb 1;11(2):1009-1017. eCollection 2018. Int J Clin Exp Pathol. 2018. PMID: 31938195 Free PMC article.
Centella asiatica (CA) is a well-known traditional Chinese herb with a long history of therapeutic uses. ...
Centella asiatica (CA) is a well-known traditional Chinese herb with a long history of therapeutic uses. ...
93 results