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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
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1996 4
1998 3
1999 2
2000 2
2001 5
2002 14
2003 8
2004 11
2005 11
2006 11
2007 21
2008 21
2009 18
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799 results

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Page 1
Fibromyalgia: Pathogenesis, Mechanisms, Diagnosis and Treatment Options Update.
Siracusa R, Paola RD, Cuzzocrea S, Impellizzeri D. Siracusa R, et al. Int J Mol Sci. 2021 Apr 9;22(8):3891. doi: 10.3390/ijms22083891. Int J Mol Sci. 2021. PMID: 33918736 Free PMC article. Review.
It is known that fibromyalgia is caused by a central sensitization phenomenon characterized by the dysfunction of neuro-circuits, which involves the perception, transmission and processing of afferent nociceptive stimuli, with the prevalent manifestation of p …
It is known that fibromyalgia is caused by a central sensitization phenomenon characterized by the dysfunction of neuro …
Effectiveness of Pain Neuroscience Education in Patients with Chronic Musculoskeletal Pain and Central Sensitization: A Systematic Review.
Lepri B, Romani D, Storari L, Barbari V. Lepri B, et al. Int J Environ Res Public Health. 2023 Feb 24;20(5):4098. doi: 10.3390/ijerph20054098. Int J Environ Res Public Health. 2023. PMID: 36901108 Free PMC article.
OBJECTIVE: To collect the available evidence about the effectiveness of pain neuroscience education (PNE) on pain, disability, and psychosocial factors in patients with chronic musculoskeletal (MSK) pain and central sensitization (CS). METHODS: A systematic review w …
OBJECTIVE: To collect the available evidence about the effectiveness of pain neuroscience education (PNE) on pain, disability, and psychosoc …
Pain Management and Rehabilitation for Central Sensitization in Temporomandibular Disorders: A Comprehensive Review.
Ferrillo M, Giudice A, Marotta N, Fortunato F, Di Venere D, Ammendolia A, Fiore P, de Sire A. Ferrillo M, et al. Int J Mol Sci. 2022 Oct 12;23(20):12164. doi: 10.3390/ijms232012164. Int J Mol Sci. 2022. PMID: 36293017 Free PMC article. Review.
In this context, myogenous TMD may present overlapping features with other disorders, such as fibromyalgia and primary headaches, characterized by chronic primary pain related to dysfunction of the central nervous system (CNS), probably through the …
In this context, myogenous TMD may present overlapping features with other disorders, such as fibromyalgia and primary headaches, cha …
The pivotal role of central sensitization in long COVID, fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome.
Goldenberg DL. Goldenberg DL. Expert Rev Neurother. 2025 Aug;25(8):973-989. doi: 10.1080/14737175.2025.2516097. Epub 2025 Jun 13. Expert Rev Neurother. 2025. PMID: 40512228 Review.
These symptoms are not related to another disease or organ damage and are similar to those in fibromyalgia and myslgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). AREAS COVERED: The similar clinical and pathophysiological features and management of long COVID, …
These symptoms are not related to another disease or organ damage and are similar to those in fibromyalgia and myslgic encephalomyeli …
Central sensitization in fibromyalgia? A systematic review on structural and functional brain MRI.
Cagnie B, Coppieters I, Denecker S, Six J, Danneels L, Meeus M. Cagnie B, et al. Semin Arthritis Rheum. 2014 Aug;44(1):68-75. doi: 10.1016/j.semarthrit.2014.01.001. Epub 2014 Jan 8. Semin Arthritis Rheum. 2014. PMID: 24508406
OBJECTIVES: The aim of the present study was to systematically review the literature addressing pain-induced changes in the brain related to central sensitization in patients with fibromyalgia (FM) using specific functional (rs-fMRI and fMRI) and structural ( …
OBJECTIVES: The aim of the present study was to systematically review the literature addressing pain-induced changes in the brain related to …
The puzzle of fibromyalgia between central sensitization syndrome and small fiber neuropathy: a narrative review on neurophysiological and morphological evidence.
de Tommaso M, Vecchio E, Nolano M. de Tommaso M, et al. Neurol Sci. 2022 Mar;43(3):1667-1684. doi: 10.1007/s10072-021-05806-x. Epub 2022 Jan 14. Neurol Sci. 2022. PMID: 35028777 Review.
Fibromyalgia (FM) is a condition characterized by chronic widespread pain whose pathogenesis is still not fully defined. Evidence based on structural and functional neuroimaging methods, electrophysiological, and morphological - skin biopsy - features demonstrated a cen …
Fibromyalgia (FM) is a condition characterized by chronic widespread pain whose pathogenesis is still not fully defined. Evidence bas …
Central sensitization syndrome and the initial evaluation of a patient with fibromyalgia: a review.
Fleming KC, Volcheck MM. Fleming KC, et al. Rambam Maimonides Med J. 2015 Apr 29;6(2):e0020. doi: 10.5041/RMMJ.10204. eCollection 2015 Apr. Rambam Maimonides Med J. 2015. PMID: 25973272 Free PMC article. Review.
In both primary care and consultative practices, patients presenting with fibromyalgia (FM) often have other medically unexplained somatic symptoms and are ultimately diagnosed as having central sensitization (CS). Central sensitization encompas …
In both primary care and consultative practices, patients presenting with fibromyalgia (FM) often have other medically unexplained so …
Acupressure attenuates fibromyalgia central sensitization via MAPK phosphorylation-mediated neuroinflammation regulation.
Liu K, Lin Y, Rao T, Huang Y, Kan Y, Liao J. Liu K, et al. J Orthop Surg Res. 2025 Jul 8;20(1):622. doi: 10.1186/s13018-025-05986-8. J Orthop Surg Res. 2025. PMID: 40629417 Free PMC article.
This study investigates how ACP modulates central sensitization and inflammatory pathways in a rat model of FM. METHODS: An FM rat model was developed to evaluate the efficacy of ACP therapy. ...CONCLUSION: ACP exerts multimodal therapeutic effects on FMS through du …
This study investigates how ACP modulates central sensitization and inflammatory pathways in a rat model of FM. METHODS: An FM …
Central sensitization in fibromyalgia and other musculoskeletal disorders.
Arendt-Nielsen L, Graven-Nielsen T. Arendt-Nielsen L, et al. Curr Pain Headache Rep. 2003 Oct;7(5):355-61. doi: 10.1007/s11916-003-0034-0. Curr Pain Headache Rep. 2003. PMID: 12946288 Review.
Increased muscle sensitivity is manifested as pain evoked by a normally non-nociceptive stimulus (allodynia), increased pain intensity evoked by nociceptive stimuli (hyperalgesia), or increased referred pain areas with associated somatosensory changes. Some manifestations of s …
Increased muscle sensitivity is manifested as pain evoked by a normally non-nociceptive stimulus (allodynia), increased pain intensity evoke …
799 results