Rheological behavior, zeta potential, and accelerated stability tests of Buriti oil (Mauritia flexuosa) emulsions containing lyotropic liquid crystals

Drug Dev Ind Pharm. 2010 Jan;36(1):93-101. doi: 10.3109/03639040903099728.

Abstract

Background: It is well known that the Amazon region presents a huge biodiversity; therefore, countless natural resources are being employed in the production of phytocosmetics and phytomedicines.

Objective: The purpose of this work was to obtain emulsions produced with Buriti oil and non-ionic surfactants.

Methods: Two surfactant systems were employed (Steareth-2 associated to Ceteareth-5 and to Ceteareth-20) to produce the emulsions using phase diagram method. Emulsions were obtained by echo-planar imaging method at 75°C. Rheological behavior and zeta potential were evaluated, and accelerated stability tests were performed.

Results: All emulsions analyzed presented pseudoplastic behavior. Zeta potential values were obtained between -14.2 and -53.3 mV. The formulations did not show changes in either physical stability, pH, or rheological behavior after accelerated stability tests. Significant differences were observed only after temperature cycling test.

Conclusion: Based on these results, the emulsions obtained could be considered as promising delivery systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carotenoids / administration & dosage*
  • Carotenoids / chemistry
  • Drug Delivery Systems*
  • Drug Stability
  • Drug Storage
  • Emulsions
  • Hydrogen-Ion Concentration
  • Liquid Crystals / chemistry
  • Plant Oils / administration & dosage*
  • Plant Oils / chemistry
  • Rheology
  • Surface-Active Agents / chemistry*
  • Temperature

Substances

  • Emulsions
  • Plant Oils
  • Surface-Active Agents
  • buriti oil
  • Carotenoids