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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 4
1988 3
1989 6
1990 25
1991 17
1992 16
1993 16
1994 11
1995 16
1996 20
1997 17
1998 14
1999 18
2000 17
2001 27
2002 14
2003 16
2004 29
2005 20
2006 27
2007 17
2008 17
2009 13
2010 18
2011 19
2012 5
2013 20
2014 18
2015 10
2016 10
2017 12
2018 9
2019 8
2020 10
2021 4
2022 7
2023 5
2024 5
2025 4

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524 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Second-generation antihistamines: a comparative review.
Slater JW, Zechnich AD, Haxby DG. Slater JW, et al. Drugs. 1999 Jan;57(1):31-47. doi: 10.2165/00003495-199957010-00004. Drugs. 1999. PMID: 9951950
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofenadine, ketotifen, loratadine, mizolastine and terfenadine, for significant features that affect choice. ...For allergic rhinitis, all agents …
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofen …
Acupuncture for allergic rhinitis: a systematic review and meta-analysis.
He M, Qin W, Qin Z, Zhao C. He M, et al. Eur J Med Res. 2022 Apr 25;27(1):58. doi: 10.1186/s40001-022-00682-3. Eur J Med Res. 2022. PMID: 35462555 Free PMC article.
No clear difference was observed between acupuncture and cetirizine or loratadine. Interestingly, trial sequential analysis (TSA) failed to confirm the aforementioned results. ...CONCLUSION: Acupuncture may have an advantage over no intervention and sham acupuncture in imp …
No clear difference was observed between acupuncture and cetirizine or loratadine. Interestingly, trial sequential analysis (TSA) fai …
The efficacy of topical cetirizine using microneedling in androgenetic alopecia male patients.
Gohary YM, Elkastawy BMM, Osama H, Abdellatif MEA. Gohary YM, et al. Arch Dermatol Res. 2025 Apr 1;317(1):665. doi: 10.1007/s00403-025-04108-y. Arch Dermatol Res. 2025. PMID: 40167621 Clinical Trial.
Researchers allocated 40 patients to undergo topical cetirizine microneedling (MN) and 40 patients to saline MN for 8 weeks. RESULTS: In the 8th week, the cetirizine group demonstrated a greater prevalence of vellus hair (70.0%) than the saline group (30.0%), with a …
Researchers allocated 40 patients to undergo topical cetirizine microneedling (MN) and 40 patients to saline MN for 8 weeks. RESULTS: …
Cetirizine inhibits gender-specific blood cell dynamics upon allergen contact in allergic rhinitis.
Jordakieva G, Kundi M, Lemell P, Zieglmayer R, Zieglmayer P, Jensen-Jarolim E, Crevenna R. Jordakieva G, et al. Clin Immunol. 2020 Jun;215:108422. doi: 10.1016/j.clim.2020.108422. Epub 2020 Apr 15. Clin Immunol. 2020. PMID: 32304734 Free article. Clinical Trial.

A more prominent thrombocyte increase in female subjects (p < .05) was noted upon allergen exposure, regardless of prior cetirizine intake. Cetirizine inhibited the mobilization of neutrophils, lymphocytes and decline in erythrocyte numbers, but did not affect th

…

A more prominent thrombocyte increase in female subjects (p < .05) was noted upon allergen exposure, regardless of prior cetirizine

…
Intravenous Cetirizine Versus Intravenous Diphenhydramine for the Treatment of Acute Urticaria: A Phase III Randomized Controlled Noninferiority Trial.
Abella BS, Berger WE, Blaiss MS, Stiell IG, Herres JP, Moellman JJ, Suner S, Kessler A, Klausner HA, Caterino JM, Du J. Abella BS, et al. Ann Emerg Med. 2020 Oct;76(4):489-500. doi: 10.1016/j.annemergmed.2020.05.025. Epub 2020 Jul 9. Ann Emerg Med. 2020. PMID: 32653333 Clinical Trial.
RESULTS: Among 262 enrolled patients, the 2-hour pruritus score change from baseline for intravenous cetirizine was statistically noninferior to that for intravenous diphenhydramine (-1.6 versus -1.5; 95% confidence interval -0.1 to 0.3), and in favor of cetirizine. …
RESULTS: Among 262 enrolled patients, the 2-hour pruritus score change from baseline for intravenous cetirizine was statistically non …
Cetirizine: a pharmacokinetic and pharmacodynamic evaluation in children with seasonal allergic rhinitis.
Watson WT, Simons KJ, Chen XY, Simons FE. Watson WT, et al. J Allergy Clin Immunol. 1989 Oct;84(4 Pt 1):457-64. doi: 10.1016/0091-6749(89)90358-8. J Allergy Clin Immunol. 1989. PMID: 2571627 Clinical Trial.
The dose-independent serum-elimination half-life of cetirizine was 7.1 +/- 1.6 hours after cetirizine, 5 mg, and 6.9 +/- 1.6 hours after cetirizine, 10 mg. Urinary excretion of unchanged cetirizine during 24 hours after the initial dose of cetirizin …
The dose-independent serum-elimination half-life of cetirizine was 7.1 +/- 1.6 hours after cetirizine, 5 mg, and 6.9 +/- 1.6 h …
Efficacy and safety of bilastine vs. levocetirizine for the treatment of chronic idiopathic urticaria: A multicenter, double-blind, double-dummy, phase III, non-inferiority, randomized clinical trial.
Chen X, Han X, Cheng B, Li H, Liu L, Geng S, Li L, Li J, Guo Q, Zhang G, Fang H, Zhang J. Chen X, et al. Chin Med J (Engl). 2024 Jun 20;137(12):1480-1482. doi: 10.1097/CM9.0000000000003071. Epub 2024 Apr 1. Chin Med J (Engl). 2024. PMID: 38557589 Free PMC article. Clinical Trial. No abstract available.
Intravenous Cetirizine vs Intravenous Diphenhydramine for the Prevention of Hypersensitivity Infusion Reactions: Results of an Exploratory Phase 2 Study.
Holmes JP, Peguero JA, Garland RC, North J, Young S, Brent LD, Joseph-Ridge N. Holmes JP, et al. J Infus Nurs. 2021 Nov-Dec 01;44(6):315-322. doi: 10.1097/NAN.0000000000000444. J Infus Nurs. 2021. PMID: 34555839 Free PMC article. Clinical Trial.
Pretreatment with antihistamines for the prevention of hypersensitivity infusion reactions is recommended for certain biologics and chemotherapies. Cetirizine is the first injectable second-generation antihistamine recently approved for acute urticaria. A randomized, explo …
Pretreatment with antihistamines for the prevention of hypersensitivity infusion reactions is recommended for certain biologics and chemothe …
Cetirizine in pollen-associated asthma.
Kurzeja A, Riedelsheimer B, Hulhoven R, Bernheim J. Kurzeja A, et al. Lancet. 1989 Mar 11;1(8637):556. doi: 10.1016/s0140-6736(89)90096-2. Lancet. 1989. PMID: 2564086 Clinical Trial. No abstract available.
Efficacy of Cetirizine 1% Versus Minoxidil 5% Topical Solution in the Treatment of Male Alopecia: A Randomized, Single-blind Controlled Study.
Hossein Mostafa D, Samadi A, Niknam S, Nasrollahi SA, Guishard A, Firooz A. Hossein Mostafa D, et al. J Pharm Pharm Sci. 2021;24:191-199. doi: 10.18433/jpps31456. J Pharm Pharm Sci. 2021. PMID: 33909554 Free article. Clinical Trial.
METHODS: Forty men, aged 18 to 49 years, were randomly divided into two equal groups to apply either cetirizine 1% or minoxidil 5% solutions. The study was divided into two phases, a 16-week treatment phase either with cetirizine or minoxidil (anagen phase), followe …
METHODS: Forty men, aged 18 to 49 years, were randomly divided into two equal groups to apply either cetirizine 1% or minoxidil 5% so …
524 results