Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2008 2
2009 1
2010 1
2012 3
2013 5
2014 2
2015 7
2016 4
2017 4
2018 2
2019 4
2020 5
2021 7
2022 3
2023 2
2024 4
2025 2
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

50 results

Results by year

Filters applied: . Clear all
Page 1
Alpha-Gal-containing biologics and anaphylaxis.
Chinuki Y, Morita E. Chinuki Y, et al. Allergol Int. 2019 Jul;68(3):296-300. doi: 10.1016/j.alit.2019.04.001. Epub 2019 Apr 30. Allergol Int. 2019. PMID: 31053502 Free article. Review.
Research has shown that the principal cause of cetuximab-induced anaphylaxis is anti-oligosaccharide IgE antibodies specific for galactose-alpha-1,3-galactose (alpha-Gal) oligosaccharide present on the mouse-derived Fab portion of the cetuximab …
Research has shown that the principal cause of cetuximab-induced anaphylaxis is anti-oligosaccharide IgE antibodies specific f …
The Immunology of Alpha-Gal Syndrome: History, Tick Bites, IgE, and Delayed Anaphylaxis to Mammalian Meat.
Platts-Mills TAE, Gangwar RS, Workman L, Wilson JM. Platts-Mills TAE, et al. Immunol Rev. 2025 Jul;332(1):e70035. doi: 10.1111/imr.70035. Immunol Rev. 2025. PMID: 40515672 Free PMC article. Review.
The primary features of the alpha-gal syndrome (AGS) are (i) The IgE ab that are causally related to anaphylaxis with infusions of Cetuximab are specific for galactose alpha-1,3-galactose. ...A further important fact is that all humans make a "natural" …
The primary features of the alpha-gal syndrome (AGS) are (i) The IgE ab that are causally related to anaphylaxis with i …
Basophil Activation Test Predicts Cetuximab Anaphylaxis Severity in Alpha-Gal IgE-Positive Patients.
Kopač P, Koren A, Bidovec-Stojkovič U, Košnik M, Dejanović L, Mesti T, Strojan P, Korošec P, Ocvirk J. Kopač P, et al. Diagnostics (Basel). 2024 Jul 1;14(13):1403. doi: 10.3390/diagnostics14131403. Diagnostics (Basel). 2024. PMID: 39001293 Free PMC article.
We prospectively recruited 38 patients and evaluated sIgE to alpha-gal in all patients before the first application of cetuximab. In all alpha-gal-sensitized patients, we evaluated skin tests to meat extracts, gelatine, and cetuximab and …
We prospectively recruited 38 patients and evaluated sIgE to alpha-gal in all patients before the first application of cetu …
Anaphylaxis to the carbohydrate side chain alpha-gal.
Platts-Mills TA, Schuyler AJ, Tripathi A, Commins SP. Platts-Mills TA, et al. Immunol Allergy Clin North Am. 2015 May;35(2):247-60. doi: 10.1016/j.iac.2015.01.009. Epub 2015 Mar 6. Immunol Allergy Clin North Am. 2015. PMID: 25841549 Free PMC article. Review.
In 2007, the monoclonal antibody cetuximab caused severe hypersensitivity reactions during the first infusion in a region of the southeastern United States. Investigation of pretreatment sera established that they contained immunoglobulin (Ig) E against the oligosaccharide …
In 2007, the monoclonal antibody cetuximab caused severe hypersensitivity reactions during the first infusion in a region of the sout …
Delayed anaphylaxis to alpha-gal, an oligosaccharide in mammalian meat.
Commins SP, Jerath MR, Cox K, Erickson LD, Platts-Mills T. Commins SP, et al. Allergol Int. 2016 Jan;65(1):16-20. doi: 10.1016/j.alit.2015.10.001. Epub 2015 Nov 21. Allergol Int. 2016. PMID: 26666477 Free PMC article. Review.
As the number of known exposures associated with anaphylaxis is limited, discovery of novel causative agents is crucial to evaluation and management of patients with idiopathic anaphylaxis. ...Our recent work has identified these responses as being due to a novel Ig …
As the number of known exposures associated with anaphylaxis is limited, discovery of novel causative agents is crucial to evaluation …
Guideline for allergological diagnosis of drug hypersensitivity reactions: S2k Guideline of the German Society for Allergology and Clinical Immunology (DGAKI) in cooperation with the German Dermatological Society (DDG), the Association of German Allergologists (ÄDA), the German Society for Pediatric Allergology (GPA), the German Contact Dermatitis Research Group (DKG), the German Society for Pneumology (DGP), the German Society of Otorhinolaryngology, Head and Neck Surgery, the Austrian Society of Allergology and Immunology (ÖGAI), the Austrian Society of Dermatology and Venereology (ÖGDV), the German Academy of Allergology and Environmental Medicine (DAAU), and the German Documentation Center for Severe Skin Reactions (dZh).
Brockow K, Wurpts G, Trautmann A, Pfützner W, Treudler R, Bircher AJ, Brehler R, Buhl T, Dickel H, Fuchs T, Jakob T, Kurz J, Kreft B, Lange L, Merk HF, Mockenhaupt M, Mülleneisen N, Ott H, Ring J, Ruëff F, Sachs B, Sitter H, Wedi B, Wöhrl S, Worm M, Zuberbier T. Brockow K, et al. Allergol Select. 2023 Aug 9;7:122-139. doi: 10.5414/ALX02422E. eCollection 2023. Allergol Select. 2023. PMID: 37705676 Free PMC article.
Fatal anaphylaxis due to alpha-gal syndrome after initial cetuximab administration: The first forensic case report.
Wen S, Unuma K, Chinuki Y, Hikino H, Uemura K. Wen S, et al. Leg Med (Tokyo). 2021 Jul;51:101878. doi: 10.1016/j.legalmed.2021.101878. Epub 2021 Apr 7. Leg Med (Tokyo). 2021. PMID: 33892262
Owing to the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal) in its heavy chain, cetuximab can induce severe IgE-dependent anaphylaxis. alpha-Gal is also the antigen responsible for alpha-gal syndrome, known as mam …
Owing to the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal) in its heavy chain, cetuximab can induce severe …
Validation of an anti-alpha-Gal IgE fluoroenzyme-immunoassay for the screening of patients at risk of severe anaphylaxis to cetuximab.
Serrier J, Davy JB, Dupont B, Clarisse B, Parienti JJ, Petit G, Khoy K, Ollivier Y, Gervais R, Mariotte D, Le Mauff B. Serrier J, et al. BMC Cancer. 2023 Jan 9;23(1):32. doi: 10.1186/s12885-023-10501-5. BMC Cancer. 2023. PMID: 36624467 Free PMC article.
BACKGROUND: The link between immediate hypersensitivity reactions (HSR) following the first cetuximab infusion and the IgE sensitization against anti-galactose-alpha-1,3-galactose (alpha-Gal) is now well-established. ...It could help avoiding cetuximab …
BACKGROUND: The link between immediate hypersensitivity reactions (HSR) following the first cetuximab infusion and the IgE sensitizat …
[Red meat allergy].
Marchal O, Allali D. Marchal O, et al. Rev Med Suisse. 2020 Apr 8;16(689):684-687. Rev Med Suisse. 2020. PMID: 32270935 Review. French.
IgE-mediated allergy to alpha-gal appears typically delayed from the consumption of meat, often three to six hours after ingestion of meat. ...The management of meat allergy consists in the avoidance of all mammalian meat (including gelatins) and other pharmaceutica …
IgE-mediated allergy to alpha-gal appears typically delayed from the consumption of meat, often three to six hours after inges …
Alpha-Gal Syndrome: An Underrated Serious Disease and a Potential Future Challenge.
Zhan M, Yin J, Xu T, Wen L. Zhan M, et al. Glob Chall. 2024 Jun 3;8(7):2300331. doi: 10.1002/gch2.202300331. eCollection 2024 Jul. Glob Chall. 2024. PMID: 39006061 Free PMC article. Review.
The allergen of this disease is not a protein but an oligosaccharide: galactose-alpha-1,3-galactose, i.e., alpha-gal or alpha-gal. Therefore, this clinical syndrome is also called alpha-gal syndrome (AGS). ...This clinical manifestation i …
The allergen of this disease is not a protein but an oligosaccharide: galactose-alpha-1,3-galactose, i.e., alpha-gal or alp …
50 results