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Skin Delivery of siRNA Using Sponge Spicules in Combination with Cationic Flexible Liposomes.
Liang X, Zhang J, Ou H, Chen J, Mitragotri S, Chen M. Liang X, et al. Mol Ther Nucleic Acids. 2020 Jun 5;20:639-648. doi: 10.1016/j.omtn.2020.04.003. Epub 2020 Apr 18. Mol Ther Nucleic Acids. 2020. PMID: 32380414 Free PMC article.
We report the topical administration of sponge Haliclona sp. Spicules (SHS) combined with cationic flexible liposomes (CFL) to increase the delivery of small interfering RNA (siRNA) into viable skin cells in vitro and in vivo. ...Subsequently, well-designed …
We report the topical administration of sponge Haliclona sp. Spicules (SHS) combined with cationic flexible liposomes (CFL) to increa …
UV-A emission from fluorescent energy-saving light bulbs alters local retinoic acid homeostasis.
Hellmann-Regen J, Heuser I, Regen F. Hellmann-Regen J, et al. Photochem Photobiol Sci. 2013 Dec;12(12):2177-85. doi: 10.1039/c3pp50206f. Photochem Photobiol Sci. 2013. PMID: 24135972
Local at-RA is anti-carcinogenic, entrains molecular rhythms and is crucial for skin homeostasis. Therefore, we quantified the impact of CFL irradiation on extra- and intracellular levels of RA isomers using an epidermal cell culture model. ...Moreover, pre-i …
Local at-RA is anti-carcinogenic, entrains molecular rhythms and is crucial for skin homeostasis. Therefore, we quantified the impact …
Mesoporous silica-coated silver nanoparticles as ciprofloxacin/siRNA carriers for accelerated infected wound healing.
Liu Q, Zhang Y, Huang J, Xu Z, Li X, Yang J, Huang H, Tang S, Chai Y, Lin J, Yang C, Liu J, Lin S. Liu Q, et al. J Nanobiotechnology. 2022 Aug 23;20(1):386. doi: 10.1186/s12951-022-01600-9. J Nanobiotechnology. 2022. PMID: 35999547 Free PMC article.
Herein, a core-shell structured Ag@MSN (silver core embedded with mesoporous silica, AM)-based nanoplatform was elaborately fabricated to co-load ciprofloxacin (CFL) and tumor necrosis factor-alpha (TNF-alpha) small interfering RNA (siTNF-alpha) (AMPC@siTNF-alpha) for trea …
Herein, a core-shell structured Ag@MSN (silver core embedded with mesoporous silica, AM)-based nanoplatform was elaborately fabricated to co …
The effects of UV emission from compact fluorescent light exposure on human dermal fibroblasts and keratinocytes in vitro.
Mironava T, Hadjiargyrou M, Simon M, Rafailovich MH. Mironava T, et al. Photochem Photobiol. 2012 Nov-Dec;88(6):1497-506. doi: 10.1111/j.1751-1097.2012.01192.x. Epub 2012 Jul 20. Photochem Photobiol. 2012. PMID: 22724459
Recently, CFL exposure was found to exacerbate existing skin conditions; however, the effects of CFL exposure on healthy skin tissue have not been thoroughly investigated. In this study, we studied the effects of exposure to CFL illumination on …
Recently, CFL exposure was found to exacerbate existing skin conditions; however, the effects of CFL exposure on health …
Diagnostic value of STMN1, LMO2, HGAL, AID expression and 1p36 chromosomal abnormalities in primary cutaneous B cell lymphomas.
Verdanet E, Dereure O, René C, Tempier A, Benammar-Hafidi A, Gallo M, Frouin E, Durand L, Gazagne I, Costes-Martineau V, Cacheux V, Szablewski V. Verdanet E, et al. Histopathology. 2017 Oct;71(4):648-660. doi: 10.1111/his.13279. Epub 2017 Jul 19. Histopathology. 2017. PMID: 28594133
Immunostaining for STMN1, LMO2, HGAL and AID allowed the distinction between CFL and CMZL, and STMN1 was the most sensitive marker (100% CFL, 0% CMZL). LMO2, HGAL and AID were positive in 93.2%, 82.1% and 86.2% CFL (all CMZL-negative). MNDA was expressed in b …
Immunostaining for STMN1, LMO2, HGAL and AID allowed the distinction between CFL and CMZL, and STMN1 was the most sensitive marker (1 …
The inhibition mechanism of the uptake of lamivudine via human organic anion transporter 1 by Stellera chamaejasme L. extracts.
Pan LY, Zeng K, Li L, Lou Y, Zeng S. Pan LY, et al. Chin J Nat Med. 2019 Sep;17(9):682-689. doi: 10.1016/S1875-5364(19)30082-2. Chin J Nat Med. 2019. PMID: 31526503
Stellera chamaejasme L. is a traditional Chinese medicine with a long history to treat stubborn skin ulcer, and it also has antiviral and antitumor effects. Neochamaejasmine B (NCB), Neochamaejasmine A (NCA) and Chamaechromone (CMC) are the major components in dried roots …
Stellera chamaejasme L. is a traditional Chinese medicine with a long history to treat stubborn skin ulcer, and it also has antiviral …
Primary Cutaneous Follicle Center Lymphomas Expressing BCL2 Protein Frequently Harbor BCL2 Gene Break and May Present 1p36 Deletion: A Study of 20 Cases.
Szablewski V, Ingen-Housz-Oro S, Baia M, Delfau-Larue MH, Copie-Bergman C, Ortonne N. Szablewski V, et al. Am J Surg Pathol. 2016 Jan;40(1):127-36. doi: 10.1097/PAS.0000000000000567. Am J Surg Pathol. 2016. PMID: 26658664
The classification of cutaneous follicular lymphoma (CFL) into primary cutaneous follicle center lymphoma (PCFCL) or secondary cutaneous follicular lymphoma (SCFL) is challenging. SCFL is suspected when tumor cells express BCL2 protein, reflecting a BCL2 translocati …
The classification of cutaneous follicular lymphoma (CFL) into primary cutaneous follicle center lymphoma (PCFCL) or secondary cutane …