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The Effect of Chia Seed on Blood Pressure, Body Composition, and Glycemic Control: A GRADE-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
TaghipourSheshdeh F, Behzadi M, Bashiri S, Mohammadi-Sartang M. TaghipourSheshdeh F, et al. Nutr Rev. 2025 Mar 1;83(3):448-465. doi: 10.1093/nutrit/nuae113. Nutr Rev. 2025. PMID: 39225983
OBJECTIVE: The aim of this study was to conduct a systematic review and meta-analysis of available randomized controlled trials to explore the effects of chia seed consumption on body weight (BW), body composition, blood pressure, and glycemic c …
OBJECTIVE: The aim of this study was to conduct a systematic review and meta-analysis of available randomized controlled trials to ex …
The Effects of Chia Seed (Salvia hispanica L.) Consumption on Blood Pressure and Body Composition in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Saadh MJ, Abosaoda MK, Baldaniya L, Kalia R, Arya R, Mishra S, Chauhan AS, Kumar A, Alizadeh M. Saadh MJ, et al. Clin Ther. 2025 Feb;47(2):168-175. doi: 10.1016/j.clinthera.2024.11.012. Epub 2024 Dec 12. Clin Ther. 2025. PMID: 39672763
PURPOSE: Growing evidence has suggested that the consumption of chia seed can decrease blood pressure and obesity in adults. However, even studies have reported uncertain findings. The current meta-analysis aimed to assess the findings of randomized …
PURPOSE: Growing evidence has suggested that the consumption of chia seed can decrease blood pressure and obesit …
Chia seed (Salvia hispanica L.) supplementation to the diet of adults with type 2 diabetes improved systolic blood pressure: A randomized controlled trial.
Alwosais EZM, Al-Ozairi E, Zafar TA, Alkandari S. Alwosais EZM, et al. Nutr Health. 2021 Jun;27(2):181-189. doi: 10.1177/0260106020981819. Epub 2021 Feb 2. Nutr Health. 2021. PMID: 33530854 Clinical Trial.
BACKGROUND: Functional food ingredients, such as dietary fiber, long-chain polyunsaturated fatty acids, and high-quality protein, have been shown to help control blood glucose concentration and lower high blood pressure (BP), as well as improving other cardio …
BACKGROUND: Functional food ingredients, such as dietary fiber, long-chain polyunsaturated fatty acids, and high-quality protein, have been …
Effect of chia seeds or concentrated fish oil on cardiometabolic risk markers in subjects with hypertriglyceridaemia: a parallel clinical trial.
Shahparvari MR, Nasrollahzadeh J. Shahparvari MR, et al. J Hum Nutr Diet. 2024 Dec;37(6):1558-1570. doi: 10.1111/jhn.13369. Epub 2024 Oct 3. J Hum Nutr Diet. 2024. PMID: 39360590 Clinical Trial.
However, no significant difference was observed between the chia seed and fish oil groups (change from baseline mean: 145.2 and 136.7 mg/dL for the chia seed and fish oil groups, respectively). The consumption of chia seeds was associated with a reduct …
However, no significant difference was observed between the chia seed and fish oil groups (change from baseline mean: 145.2 an …
Effects of chia seed (Salvia hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs.
Karimi M, Pirzad S, Shirsalimi N, Ahmadizad S, Hashemi SM, Karami S, Kazemi K, Shahir-Roudi E, Aminzadeh A. Karimi M, et al. Nutr Metab (Lond). 2024 Sep 16;21(1):74. doi: 10.1186/s12986-024-00847-3. Nutr Metab (Lond). 2024. PMID: 39285289 Free PMC article. Review.

There was no significant effect on body mass index (BMI) (MD: 0.1 kg/m(2), p = 0.91), but a significant reduction in waist circumference (WC) (MD: - 2.82 cm, p < 0.001) was noted. Additionally, chia seed supplementation resulted in a significant reduction in syst

…
There was no significant effect on body mass index (BMI) (MD: 0.1 kg/m(2), p = 0.91), but a significant reduction in waist circumference (WC …
Clinical evidence on dietary supplementation with chia seed (Salvia hispanica L.): a systematic review and meta-analysis.
Teoh SL, Lai NM, Vanichkulpitak P, Vuksan V, Ho H, Chaiyakunapruk N. Teoh SL, et al. Nutr Rev. 2018 Apr 1;76(4):219-242. doi: 10.1093/nutrit/nux071. Nutr Rev. 2018. PMID: 29452425
STUDY SELECTION: Randomized controlled trials that assessed the clinical effects of chia seed consumption in human participants were included. ...Pooling of results showed no significant differences except for the following findings of subgroup analysis at hi …
STUDY SELECTION: Randomized controlled trials that assessed the clinical effects of chia seed consumption in human part …
EFFECT OF CHIA SEED (SALVIA HISPANICA L.) CONSUMPTION ON CARDIOVASCULAR RISK FACTORS IN HUMANS: A SYSTEMATIC REVIEW.
de Souza Ferreira C, dd Sousa Fomes Lde F, da Silva GE, Rosa G. de Souza Ferreira C, et al. Nutr Hosp. 2015 Nov 1;32(5):1909-18. doi: 10.3305/nh.2015.32.5.9394. Nutr Hosp. 2015. PMID: 26545644 Free article.
AIM: to systematize the findings of studies assessing the effect the consumption of chia seed, either milled or whole, has in the prevention/control of cardiovascular risk factors in humans. ...Of the chia seed interventions, one study showed a signifi …
AIM: to systematize the findings of studies assessing the effect the consumption of chia seed, either milled or whole, has in …
Chia seed supplementation and disease risk factors in overweight women: a metabolomics investigation.
Nieman DC, Gillitt N, Jin F, Henson DA, Kennerly K, Shanely RA, Ore B, Su M, Schwartz S. Nieman DC, et al. J Altern Complement Med. 2012 Jul;18(7):700-8. doi: 10.1089/acm.2011.0443. J Altern Complement Med. 2012. PMID: 22830971 Clinical Trial.
DESIGN/INTERVENTION: Subjects were randomized to chia seed (whole or milled) and placebo (poppy seed) groups, and under double-blinded procedures ingested 25 g chia seed or placebo supplements each day for 10 weeks. ...Pre-to-post measures of bo …
DESIGN/INTERVENTION: Subjects were randomized to chia seed (whole or milled) and placebo (poppy seed) groups, and under …
Effects of chia (Salvia hispanica. L) on anthropometric measures and other cardiometabolic risk factors: A systematic review and dose-response meta-analysis.
Kiani S, Naghshi S, Saghafi-Asl M. Kiani S, et al. Complement Ther Med. 2024 Nov;86:103086. doi: 10.1016/j.ctim.2024.103086. Epub 2024 Sep 17. Complement Ther Med. 2024. PMID: 39299654 Free article.
The results showed a significant reduction in systolic blood pressure (SBP) (MD = -7.87 mmHg; 95 % CI: - 12.92 to - 2.82; I(2) = 71.3 %, P (heterogeneity) = 0.004), diastolic blood pressure (MD = -6.33 mmHg; 95 %CI: - 7.33 to - 5.34, I(2) = 0 %, P (het …
The results showed a significant reduction in systolic blood pressure (SBP) (MD = -7.87 mmHg; 95 % CI: - 12.92 to - 2.82; I(2) …
Chia seed does not promote weight loss or alter disease risk factors in overweight adults.
Nieman DC, Cayea EJ, Austin MD, Henson DA, McAnulty SR, Jin F. Nieman DC, et al. Nutr Res. 2009 Jun;29(6):414-8. doi: 10.1016/j.nutres.2009.05.011. Nutr Res. 2009. PMID: 19628108 Clinical Trial.
Subjects were randomized to chia seed (CS) and placebo (P) groups, and under single-blinded procedures, ingested 25 g CS or P supplements mixed in 0.25 L water twice daily before the first and last meal for 12 weeks. ...Pre- and poststudy measures included bo …
Subjects were randomized to chia seed (CS) and placebo (P) groups, and under single-blinded procedures, ingested 25 g C …
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