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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1971 1
1973 1
1975 1
1976 1
1977 2
1978 3
1979 2
1981 4
1982 3
1983 2
1984 5
1985 6
1986 6
1987 16
1988 11
1989 19
1990 18
1991 32
1992 25
1993 27
1994 31
1995 26
1996 34
1997 36
1998 30
1999 32
2000 40
2001 39
2002 51
2003 42
2004 58
2005 62
2006 69
2007 63
2008 82
2009 67
2010 74
2011 94
2012 128
2013 117
2014 104
2015 118
2016 118
2017 117
2018 99
2019 94
2020 103
2021 120
2022 122
2023 96
2024 112
2025 113
2026 46

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2,411 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Povidone Iodine vs Chlorhexidine Gluconate in Alcohol for Preoperative Skin Antisepsis: A Randomized Clinical Trial.
Widmer AF, Atkinson A, Kuster SP, Wolfensberger A, Klimke S, Sommerstein R, Eckstein FS, Schoenhoff F, Beldi G, Gutschow CA, Marschall J, Schweiger A, Jent P. Widmer AF, et al. JAMA. 2024 Aug 20;332(7):541-549. doi: 10.1001/jama.2024.8531. JAMA. 2024. PMID: 38884982 Free PMC article. Clinical Trial.
The choice of antiseptic agent, povidone iodine or chlorhexidine gluconate, remains debated. OBJECTIVE: To determine whether povidone iodine in alcohol is noninferior to chlorhexidine gluconate in alcohol to prevent SSIs after cardiac or abdominal surgery. ...In car …
The choice of antiseptic agent, povidone iodine or chlorhexidine gluconate, remains debated. OBJECTIVE: To determine whether povidone …
Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.
Darouiche RO, Wall MJ Jr, Itani KM, Otterson MF, Webb AL, Carrick MM, Miller HJ, Awad SS, Crosby CT, Mosier MC, Alsharif A, Berger DH. Darouiche RO, et al. N Engl J Med. 2010 Jan 7;362(1):18-26. doi: 10.1056/NEJMoa0810988. N Engl J Med. 2010. PMID: 20054046 Free article. Clinical Trial.
We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iodine. METHODS: We randomly assigned adults undergoing clean-contaminated surgery in six hospitals to preoperative skin preparation with eithe …
We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iod …
Should oral chlorhexidine remain in ventilator-associated pneumonia prevention bundles?
Vieira PC, de Oliveira RB, da Silva Mendonça TM. Vieira PC, et al. Med Intensiva (Engl Ed). 2022 May;46(5):259-268. doi: 10.1016/j.medine.2020.09.010. Med Intensiva (Engl Ed). 2022. PMID: 35598950 Review.
Recent studies have questioned the safety and effectiveness of oral chlorhexidine to prevent VAP. We sought to verify whether the adverse effects of this substance outweigh its benefits. We searched several databases and selected studies that investigated the use of oral …
Recent studies have questioned the safety and effectiveness of oral chlorhexidine to prevent VAP. We sought to verify whether the adv …
Chlorhexidine mouthrinse as an adjunctive treatment for gingival health.
James P, Worthington HV, Parnell C, Harding M, Lamont T, Cheung A, Whelton H, Riley P. James P, et al. Cochrane Database Syst Rev. 2017 Mar 31;3(3):CD008676. doi: 10.1002/14651858.CD008676.pub2. Cochrane Database Syst Rev. 2017. PMID: 28362061 Free PMC article.
Mechanical oral hygiene procedures were toothbrushing with/without the use of dental floss or interdental cleaning aids and could include professional tooth cleaning/periodontal treatment.To determine whether the effect of chlorhexidine mouthrinse is influenced by chlor …
Mechanical oral hygiene procedures were toothbrushing with/without the use of dental floss or interdental cleaning aids and could include pr …
Preoperative Antisepsis with Chlorhexidine Versus Povidone-Iodine for the Prevention of Surgical Site Infection: a Systematic Review and Meta-analysis.
Chen S, Chen JW, Guo B, Xu CC. Chen S, et al. World J Surg. 2020 May;44(5):1412-1424. doi: 10.1007/s00268-020-05384-7. World J Surg. 2020. PMID: 31996985
BACKGROUND AND OBJECTIVE: Chlorhexidine (CH) and povidone-iodine (PI) are the most commonly used preoperative skin antiseptics at present. ...This meta-analysis aimed to evaluate the efficacy of chlorhexidine and povidone-iodine in the prevention of postoperative su …
BACKGROUND AND OBJECTIVE: Chlorhexidine (CH) and povidone-iodine (PI) are the most commonly used preoperative skin antiseptics at pre …
Improving central venous catheter care with chlorhexidine gluconate dressings: evidence from a systematic review and Meta-analysis.
Xu H, Zhu M, Xu S, Bian L. Xu H, et al. J Health Popul Nutr. 2024 Nov 1;43(1):177. doi: 10.1186/s41043-024-00672-7. J Health Popul Nutr. 2024. PMID: 39487464 Free PMC article.
RESULTS: The final analysis included 14 RCTs involving a total of 8920 patients with CVCs, with participants divided into a chlorhexidine antibacterial dressing group (n = 4731) and a control group (n = 4189). The chlorhexidine dressing group demonstrated a statisti …
RESULTS: The final analysis included 14 RCTs involving a total of 8920 patients with CVCs, with participants divided into a chlorhexidine …
Chlorhexidine vs Routine Foot Washing to Prevent Diabetic Foot Ulcers: A Randomized Clinical Trial.
Lydecker AD, Kim JJ, Robinson GL, Johnson JK, Brown CH, Petruccelli CC, Terrin ML, Margolis DJ, Roghmann MC. Lydecker AD, et al. JAMA Netw Open. 2025 Feb 3;8(2):e2460087. doi: 10.1001/jamanetworkopen.2024.60087. JAMA Netw Open. 2025. PMID: 39964684 Free PMC article. Clinical Trial.
Participants were randomly assigned 1:1 to receive either soap-and-water wipes (control group) or 2% chlorhexidine wipes (chlorhexidine group). Intention-to-treat data analysis was conducted from October 5, 2023, to April 24, 2024. ...Both chlorhexidine and c …
Participants were randomly assigned 1:1 to receive either soap-and-water wipes (control group) or 2% chlorhexidine wipes (chlorhex …
Antimicrobial efficacy of Xylitol, Probiotic and Chlorhexidine mouth rinses among children and elderly population at high risk for dental caries - A Randomized Controlled Trial.
Krupa NC, Thippeswamy HM, Chandrashekar BR. Krupa NC, et al. J Prev Med Hyg. 2022 Jul 31;63(2):E282-E287. doi: 10.15167/2421-4248/jpmh2022.63.2.1772. eCollection 2022 Jun. J Prev Med Hyg. 2022. PMID: 35968060 Free PMC article. Clinical Trial.
INTRODUCTION: Chlorhexidine is considered the most potent chemotherapeutic agent against Streptococcus mutans. ...CONCLUSIONS: Antimicrobial efficacy of xylitol and probiotic mouth rinses were comparable to that of chlorhexidine in both children and elderly. Probiot …
INTRODUCTION: Chlorhexidine is considered the most potent chemotherapeutic agent against Streptococcus mutans. ...CONCLUSIONS: Antimi …
Chlorhexidine-based versus non-chlorhexidine dressings to prevent catheter-related bloodstream infections: An evidence-based review.
Azzopardi A, Trapani J. Azzopardi A, et al. Nurs Crit Care. 2024 Jan;29(1):191-195. doi: 10.1111/nicc.12879. Epub 2022 Dec 28. Nurs Crit Care. 2024. PMID: 36579384 Review.
Sterile gauze or transparent polyurethane dressings are conventionally used as extraluminal barriers; however, antimicrobial chlorhexidine CVC dressings could potentially reduce infection risk. This short evidence-based review examined the literature comparing the effectiv …
Sterile gauze or transparent polyurethane dressings are conventionally used as extraluminal barriers; however, antimicrobial chlorhexidin …
Chlorhexidine disinfectant can reduce the risk of central venous catheter infection compared with povidone: a meta-analysis.
Shi Y, Yang N, Zhang L, Zhang M, Pei HH, Wang H. Shi Y, et al. Am J Infect Control. 2019 Oct;47(10):1255-1262. doi: 10.1016/j.ajic.2019.02.024. Epub 2019 Apr 2. Am J Infect Control. 2019. PMID: 30948152 Review.
OBJECTIVE: Assess the efficacy of chlorhexidine with povidone solutions as a skin disinfectant for central venous catheter (CVC) care. ...Compared with povidone, the chlorhexidine catheterization rate of CRBSIs was reduced (P = .16; I(2) = 32%; RR = 0.54; 95% CI, 0. …
OBJECTIVE: Assess the efficacy of chlorhexidine with povidone solutions as a skin disinfectant for central venous catheter (CVC) care …
2,411 results