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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
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2001 2
2003 4
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61 results

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Page 1
Antipsychotic agents and QT changes.
Welch R, Chue P. Welch R, et al. J Psychiatry Neurosci. 2000 Mar;25(2):154-60. J Psychiatry Neurosci. 2000. PMID: 10740988 Free PMC article. Review.
Lengthening of the QT interval can be associated with a fatal paroxysmal ventricular arrhythmia known as torsades de pointes. The specific duration of the QT interval at which the risk of an adverse cardiac event is greatest, is not established. ...
Lengthening of the QT interval can be associated with a fatal paroxysmal ventricular arrhythmia known as torsades de pointes. …
Electrocardiogram and cardiovascular changes in thioridazine and chlorpromazine poisoning.
Strachan EM, Kelly CA, Bateman DN. Strachan EM, et al. Eur J Clin Pharmacol. 2004 Oct;60(8):541-5. doi: 10.1007/s00228-004-0811-7. Epub 2004 Sep 15. Eur J Clin Pharmacol. 2004. PMID: 15372128
For chlorpromazine, there was no dose-response relationship for ECG changes, but there was a significant dose-response relationship for increasing heart rate and reduction in mean blood pressure. CONCLUSIONS: We have confirmed a relationship between increasing dose of thio …
For chlorpromazine, there was no dose-response relationship for ECG changes, but there was a significant dose-response relationship f …
Effect of long-term use of antipsychotics on the ventricular repolarization index.
Liu Q, Yuan X, Sheng C, Cai W, Geng X, Liu H, Song S. Liu Q, et al. BMC Psychiatry. 2024 Jul 16;24(1):505. doi: 10.1186/s12888-024-05947-1. BMC Psychiatry. 2024. PMID: 39014414 Free PMC article.
The types and doses of drugs taken at 5 time points were recorded and converted into chlorpromazine equivalents for comparison. The incidence of arrhythmia during the observation cycle was recorded. RESULTS: The patients had been treated with antipsychotic medication for 4 …
The types and doses of drugs taken at 5 time points were recorded and converted into chlorpromazine equivalents for comparison. The i …
[Antipsychotic drugs and cardiovascular safety: current studies of prolonged QT interval and risk of ventricular arrhythmia].
Gury C, Canceil O, Iaria P. Gury C, et al. Encephale. 2000 Nov-Dec;26(6):62-72. Encephale. 2000. PMID: 11217540 Review. French.
Most antipsychotic agents show electrophysiological effects resembling those of class 1a antiarrhythmic agents, and may be responsible for prolonging the QT interval, potentially going on to cause torsades de pointes. Some of the antipsychotic agents carry a high ri …
Most antipsychotic agents show electrophysiological effects resembling those of class 1a antiarrhythmic agents, and may be responsible for p …
Ziprasidone for schizophrenia and bipolar disorder: a review of the clinical trials.
Greenberg WM, Citrome L. Greenberg WM, et al. CNS Drug Rev. 2007 Summer;13(2):137-77. doi: 10.1111/j.1527-3458.2007.00008.x. CNS Drug Rev. 2007. PMID: 17627670 Free PMC article. Review.
Oral ziprasidone appears efficacious, and has been shown to have some limited clinical advantages over chlorpromazine and haloperidol in ameliorating negative symptoms of schizophrenia. In Phase 2 of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) f …
Oral ziprasidone appears efficacious, and has been shown to have some limited clinical advantages over chlorpromazine and haloperidol …
Do women have more adverse drug reactions?
Rademaker M. Rademaker M. Am J Clin Dermatol. 2001;2(6):349-51. doi: 10.2165/00128071-200102060-00001. Am J Clin Dermatol. 2001. PMID: 11770389 Review.
There are pharmacodynamic differences between men and women, seen particularly with cardiac and psychotropic medications. There is no doubt that chlorpromazine, fluspirilene and various antipsychotics appear more effective in women than men for the same dosage and plasma c …
There are pharmacodynamic differences between men and women, seen particularly with cardiac and psychotropic medications. There is no doubt …
Determinants/Predictors of QT Abnormalities in Patients on Psychotropic Medications in a Nigerian Tertiary Hospital.
Ojo OE, Ajayi EA, Ajayi AO, Fadare JO, Dada SA, Olaoye OB. Ojo OE, et al. Cardiovasc Toxicol. 2024 Jul;24(7):700-709. doi: 10.1007/s12012-024-09873-2. Epub 2024 May 31. Cardiovasc Toxicol. 2024. PMID: 38819736
We studied the effects of various psychotropic drugs on QT dispersion (QTd) and corrected QT interval (QTc) as well as correlation with the types and dosages of psychotropic drugs used. ...Age, heart rate and antipsychotic dose in chlorpromazine equivalent we …
We studied the effects of various psychotropic drugs on QT dispersion (QTd) and corrected QT interval (QTc) as well as correla …
Drug-drug interactions between COVID-19 treatments and antipsychotics drugs: integrated evidence from 4 databases and a systematic review.
Plasencia-García BO, Rodríguez-Menéndez G, Rico-Rangel MI, Rubio-García A, Torelló-Iserte J, Crespo-Facorro B. Plasencia-García BO, et al. Psychopharmacology (Berl). 2021 Feb;238(2):329-340. doi: 10.1007/s00213-020-05716-4. Epub 2021 Jan 7. Psychopharmacology (Berl). 2021. PMID: 33410987 Free PMC article.
EVIDENCE REVIEW: Three databases were consulted: Lexicomp Drug Interactions, Micromedex Solutions Drugs Interactions, and Liverpool Drug Interaction Group for COVID-19 therapies. To acquire more information on QT prolongation and Torsade de Pointes (TdP), the Cre …
EVIDENCE REVIEW: Three databases were consulted: Lexicomp Drug Interactions, Micromedex Solutions Drugs Interactions, and Liverpool Drug …
Prolonged QT Risk Assessment in Antipsychotic Overdose Using the QT Nomogram.
Berling I, Isbister GK. Berling I, et al. Ann Emerg Med. 2015 Aug;66(2):154-64. doi: 10.1016/j.annemergmed.2014.12.005. Epub 2015 Jan 30. Ann Emerg Med. 2015. PMID: 25639523
STUDY OBJECTIVE: Antipsychotic drugs are frequently reported to cause QT prolongation and torsade de pointes. We aim to investigate the potential risk of torsade de pointes in antipsychotic overdose by assessing the QT interval with the QT nomog …
STUDY OBJECTIVE: Antipsychotic drugs are frequently reported to cause QT prolongation and torsade de pointes. We aim to invest …
61 results