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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1981 1
1983 1
1984 1
1985 3
1987 5
1988 2
1989 5
1990 5
1991 10
1992 11
1993 5
1994 3
1995 2
1996 5
1997 4
1998 7
1999 12
2000 11
2001 15
2002 8
2003 10
2004 10
2005 10
2006 9
2007 14
2008 13
2009 7
2010 15
2011 7
2012 11
2013 12
2014 12
2015 19
2016 20
2017 23
2018 22
2019 15
2020 10
2021 11
2022 4
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Search Results

337 results
Results by year
Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials.
Simental-Mendía M, Sánchez-García A, Vilchez-Cavazos F, Acosta-Olivo CA, Peña-Martínez VM, Simental-Mendía LE. Simental-Mendía M, et al. Rheumatol Int. 2018 Aug;38(8):1413-1428. doi: 10.1007/s00296-018-4077-2. Epub 2018 Jun 11. Rheumatol Int. 2018. PMID: 29947998 Review.
Although glucosamine and chondroitin sulfate have showed beneficial effects on joint tissues in osteoarthritis (OA), their therapeutic use in the clinical setting is still debatable. ...Oral supplementation with glucosamine or chondroitin sulfate reduc …
Although glucosamine and chondroitin sulfate have showed beneficial effects on joint tissues in osteoarthritis (OA), their the …
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis.
Clegg DO, Reda DJ, Harris CL, Klein MA, O'Dell JR, Hooper MM, Bradley JD, Bingham CO 3rd, Weisman MH, Jackson CG, Lane NE, Cush JJ, Moreland LW, Schumacher HR Jr, Oddis CV, Wolfe F, Molitor JA, Yocum DE, Schnitzer TJ, Furst DE, Sawitzke AD, Shi H, Brandt KD, Moskowitz RW, Williams HJ. Clegg DO, et al. N Engl J Med. 2006 Feb 23;354(8):795-808. doi: 10.1056/NEJMoa052771. N Engl J Med. 2006. PMID: 16495392 Free article. Clinical Trial.
METHODS: We randomly assigned 1583 patients with symptomatic knee osteoarthritis to receive 1500 mg of glucosamine daily, 1200 mg of chondroitin sulfate daily, both glucosamine and chondroitin sulfate, 200 mg of celecoxib daily, or placebo for 24 weeks …
METHODS: We randomly assigned 1583 patients with symptomatic knee osteoarthritis to receive 1500 mg of glucosamine daily, 1200 mg of chon
Comparison of Glucosamine-Chondroitin Sulfate with and without Methylsulfonylmethane in Grade I-II Knee Osteoarthritis: A Double Blind Randomized Controlled Trial.
Lubis AMT, Siagian C, Wonggokusuma E, Marsetyo AF, Setyohadi B. Lubis AMT, et al. Acta Med Indones. 2017 Apr;49(2):105-111. Acta Med Indones. 2017. PMID: 28790224 Free article. Clinical Trial.
Methylsulfonylmethane (MSM) is a supplement containing organic sulphur and also reported to slow anatomical joint progressivity in the knee OA. The MSM is often combined with glucosamine and chondroitin sulfate. However, there are controversies whether glucosamine- …
Methylsulfonylmethane (MSM) is a supplement containing organic sulphur and also reported to slow anatomical joint progressivity in the knee …
Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib.
Hochberg MC, Martel-Pelletier J, Monfort J, Möller I, Castillo JR, Arden N, Berenbaum F, Blanco FJ, Conaghan PG, Doménech G, Henrotin Y, Pap T, Richette P, Sawitzke A, du Souich P, Pelletier JP; MOVES Investigation Group. Hochberg MC, et al. Ann Rheum Dis. 2016 Jan;75(1):37-44. doi: 10.1136/annrheumdis-2014-206792. Epub 2015 Jan 14. Ann Rheum Dis. 2016. PMID: 25589511 Free PMC article. Clinical Trial.
OBJECTIVES: To compare the efficacy and safety of chondroitin sulfate plus glucosamine hydrochloride (CS+GH) versus celecoxib in patients with knee osteoarthritis and severe pain. ...
OBJECTIVES: To compare the efficacy and safety of chondroitin sulfate plus glucosamine hydrochloride (CS+GH) versus celecoxib …
Does glucosamine, chondroitin sulfate, and methylsulfonylmethane supplementation improve the outcome of temporomandibular joint osteoarthritis management with arthrocentesis plus intraarticular hyaluronic acid injection. A randomized clinical trial.
Cömert Kılıç S. Cömert Kılıç S. J Craniomaxillofac Surg. 2021 Aug;49(8):711-718. doi: 10.1016/j.jcms.2021.02.012. Epub 2021 Feb 22. J Craniomaxillofac Surg. 2021. PMID: 33685850 Clinical Trial.
The purpose of this study was to compare clinical outcomes obtained with the use of glucosamine, chondroitin sulfate, and methylsulfonylmethane (GCM) supplementation after arthrocentesis plus intraarticular hyaluronic acid (HA) injection. ...
The purpose of this study was to compare clinical outcomes obtained with the use of glucosamine, chondroitin sulfate, and meth …
Chondroitin for osteoarthritis.
Singh JA, Noorbaloochi S, MacDonald R, Maxwell LJ. Singh JA, et al. Cochrane Database Syst Rev. 2015 Jan 28;1(1):CD005614. doi: 10.1002/14651858.CD005614.pub2. Cochrane Database Syst Rev. 2015. PMID: 25629804 Free PMC article. Review.
BACKGROUND: Osteoarthritis, a common joint disorder, is one of the leading causes of disability. Chondroitin has emerged as a new treatment. Previous meta-analyses have shown contradictory results on the efficacy of chondroitin. ...More high-quality studies are need …
BACKGROUND: Osteoarthritis, a common joint disorder, is one of the leading causes of disability. Chondroitin has emerged as a new tre …
Effect of an oral preparation containing hyaluronic acid, chondroitin sulfate, hydrolyzed collagen type II and hydrolyzed keratin on synovial fluid features and clinical indices in knee osteoarthritis. A pilot study.
Oliviero F, Ramonda R, Hoxha A, Scanu A, Galozzi P, Favero M, Frallonardo P, Punzi L. Oliviero F, et al. Reumatismo. 2020 Nov 19;72(3):125-130. doi: 10.4081/reumatismo.2020.1272. Reumatismo. 2020. PMID: 33213125 Free article. Clinical Trial.
The aim of this study was to evaluate the effect of an oral preparation containing a naturally occurring matrix of hydrolyzed collagen type II, chondroitin sulfate (CS), and hyaluronic acid (HA), and bioactive oligopeptides of natural hydrolyzed keratin (K) in patie …
The aim of this study was to evaluate the effect of an oral preparation containing a naturally occurring matrix of hydrolyzed collagen type …
Association of Pharmacological Treatments With Long-term Pain Control in Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis.
Gregori D, Giacovelli G, Minto C, Barbetta B, Gualtieri F, Azzolina D, Vaghi P, Rovati LC. Gregori D, et al. JAMA. 2018 Dec 25;320(24):2564-2579. doi: 10.1001/jama.2018.19319. JAMA. 2018. PMID: 30575881 Free PMC article.
The association with pain improvement remained significant only for glucosamine sulfate when data were analyzed using the mean difference on a scale from 0 to 100 and when trials at high risk of bias were excluded. Associations with improvement in joint space narrowing wer …
The association with pain improvement remained significant only for glucosamine sulfate when data were analyzed using the mean differ …
Glucosamine and chondroitin for knee osteoarthritis: a double-blind randomised placebo-controlled clinical trial evaluating single and combination regimens.
Fransen M, Agaliotis M, Nairn L, Votrubec M, Bridgett L, Su S, Jan S, March L, Edmonds J, Norton R, Woodward M, Day R; LEGS study collaborative group. Fransen M, et al. Ann Rheum Dis. 2015 May;74(5):851-8. doi: 10.1136/annrheumdis-2013-203954. Epub 2014 Jan 6. Ann Rheum Dis. 2015. PMID: 24395557 Clinical Trial.
OBJECTIVE: To determine if the dietary supplements, glucosamine and/or chondroitin, result in reduced joint space narrowing (JSN) and pain among people with symptomatic knee osteoarthritis. METHODS: A double-blind randomised placebo-controlled clinical trial with 2-year fo …
OBJECTIVE: To determine if the dietary supplements, glucosamine and/or chondroitin, result in reduced joint space narrowing (JSN) and …
Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study.
Lugo JP, Saiyed ZM, Lane NE. Lugo JP, et al. Nutr J. 2016 Jan 29;15:14. doi: 10.1186/s12937-016-0130-8. Nutr J. 2016. PMID: 26822714 Free PMC article. Clinical Trial.
The purpose of this study was to evaluate the efficacy and tolerability of UC-II for knee osteoarthritis (OA) pain and associated symptoms compared to placebo and to glucosamine hydrochloride plus chondroitin sulfate (GC). METHODS: One hundred ninety one volunteers …
The purpose of this study was to evaluate the efficacy and tolerability of UC-II for knee osteoarthritis (OA) pain and associated symptoms c …
337 results