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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
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1968 2
1969 3
1970 8
1971 29
1972 47
1973 40
1974 77
1975 105
1976 125
1977 77
1978 110
1979 82
1980 88
1981 77
1982 96
1983 87
1984 101
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1986 128
1987 107
1988 113
1989 111
1990 133
1991 152
1992 166
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1998 434
1999 474
2000 597
2001 697
2002 820
2003 998
2004 1228
2005 1242
2006 1282
2007 1289
2008 1397
2009 1468
2010 1529
2011 1720
2012 1737
2013 1785
2014 1679
2015 1636
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2018 1376
2019 1432
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2023 1084
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2025 1265
2026 728

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36,545 results

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Page 1
Chromatin Immunoprecipitation.
Wiehle L, Breiling A. Wiehle L, et al. Methods Mol Biol. 2016;1480:7-21. doi: 10.1007/978-1-4939-6380-5_2. Methods Mol Biol. 2016. PMID: 27659971
Chromatin immunoprecipitation (ChIP) is a valuable method to investigate protein-DNA interactions in vivo. Since its discovery it has been indispensable to identify binding sites and patterns of a variety of DNA-interacting proteins, such as transcript …
Chromatin immunoprecipitation (ChIP) is a valuable method to investigate protein-DNA interactions in vivo. Since its discovery …
Myeloperoxidase transforms chromatin into neutrophil extracellular traps.
Burn GL, Raisch T, Tacke S, Winkler M, Prumbaum D, Thee S, Gimber N, Raunser S, Zychlinsky A. Burn GL, et al. Nature. 2025 Nov;647(8090):747-756. doi: 10.1038/s41586-025-09523-9. Epub 2025 Sep 17. Nature. 2025. PMID: 40963017 Free PMC article.
As a consequence, dimeric MPO displaces DNA from the core complex, culminating in nucleosome disassembly. On the other hand, MPO monomers stably interact with the nucleosome acidic patch without making concomitant DNA contacts, explaining how monomeric MPO binds …
As a consequence, dimeric MPO displaces DNA from the core complex, culminating in nucleosome disassembly. On the other hand, MPO mono …
DNA-binding and chromatin localization properties of CHD1.
Stokes DG, Perry RP. Stokes DG, et al. Mol Cell Biol. 1995 May;15(5):2745-53. doi: 10.1128/MCB.15.5.2745. Mol Cell Biol. 1995. PMID: 7739555 Free PMC article.
CHD1 is a novel DNA-binding protein that contains both a chromatin organization modifier (chromo) domain and a helicase/ATPase domain. We show here that CHD1 preferentially binds to relatively long A.T tracts in double-stranded DNA via minor-gro …
CHD1 is a novel DNA-binding protein that contains both a chromatin organization modifier (chromo) domain and a helicase …
DNA methylation and chromatin structure.
Lewis J, Bird A. Lewis J, et al. FEBS Lett. 1991 Jul 22;285(2):155-9. doi: 10.1016/0014-5793(91)80795-5. FEBS Lett. 1991. PMID: 1855583 Review.
As well as affecting chromatin structure. DNA methylation also represses transcription. A protein (MeCP) which binds specifically to methylated DNA has been identified. The properties of MeCP could account for the effects of DNA methylation on b …
As well as affecting chromatin structure. DNA methylation also represses transcription. A protein (MeCP) which binds sp …
Histones with an unconventional DNA-binding mode in vitro are major chromatin constituents in the bacterium Bdellovibrio bacteriovorus.
Hocher A, Laursen SP, Radford P, Tyson J, Lambert C, Stevens KM, Montoya A, Shliaha PV, Picardeau M, Sockett RE, Luger K, Warnecke T. Hocher A, et al. Nat Microbiol. 2023 Nov;8(11):2006-2019. doi: 10.1038/s41564-023-01492-x. Epub 2023 Oct 9. Nat Microbiol. 2023. PMID: 37814071 Free PMC article.
Crystal structures (<2.0 A) of the B. bacteriovorus histone (Bd0055) dimer and the histone-DNA complex confirm conserved histone-fold topology but indicate a distinct DNA-binding mode. Unlike known histones in eukaryotes, archaea and viruses, Bd0055 bin …
Crystal structures (<2.0 A) of the B. bacteriovorus histone (Bd0055) dimer and the histone-DNA complex confirm conserved histone-f …
Uncovering the Relationship between Tissue-Specific TF-DNA Binding and Chromatin Features through a Transformer-Based Model.
Zhang Y, Liu Y, Wang Z, Wang M, Xiong S, Huang G, Gong M. Zhang Y, et al. Genes (Basel). 2022 Oct 26;13(11):1952. doi: 10.3390/genes13111952. Genes (Basel). 2022. PMID: 36360189 Free PMC article.
Chromatin features can reveal tissue-specific TF-DNA binding, which leads to a better understanding of many critical physiological processes. Accurately identifying TF-DNA bindings and constructing their relationships with chromatin featu …
Chromatin features can reveal tissue-specific TF-DNA binding, which leads to a better understanding of many critical ph …
Chromatin landscape dictates HSF binding to target DNA elements.
Guertin MJ, Lis JT. Guertin MJ, et al. PLoS Genet. 2010 Sep 9;6(9):e1001114. doi: 10.1371/journal.pgen.1001114. PLoS Genet. 2010. PMID: 20844575 Free PMC article.
Sequence-specific transcription factors (TFs) are critical for specifying patterns and levels of gene expression, but target DNA elements are not sufficient to specify TF binding in vivo. In eukaryotes, the binding of a TF is in competition with a constellati …
Sequence-specific transcription factors (TFs) are critical for specifying patterns and levels of gene expression, but target DNA elem …
H3K36me2/3 Binding and DNA Binding of the DNA Methyltransferase DNMT3A PWWP Domain Both Contribute to its Chromatin Interaction.
Dukatz M, Holzer K, Choudalakis M, Emperle M, Lungu C, Bashtrykov P, Jeltsch A. Dukatz M, et al. J Mol Biol. 2019 Dec 6;431(24):5063-5074. doi: 10.1016/j.jmb.2019.09.006. Epub 2019 Oct 18. J Mol Biol. 2019. PMID: 31634469
Here, we show that the PWWP domain of mouse DNMT3A binds to H3K36me2 and H3K36me3 with a slight preference for H3K36me2. PWWP domains have also been reported to bind to DNA, and the close proximity of H3K36 and nucleosomal DNA suggests a combined binding …
Here, we show that the PWWP domain of mouse DNMT3A binds to H3K36me2 and H3K36me3 with a slight preference for H3K36me2. PWWP domains …
Binding of Drosophila maternal Mamo protein to chromatin and specific DNA sequences.
Hira S, Okamoto T, Fujiwara M, Kita H, Kobayashi S, Mukai M. Hira S, et al. Biochem Biophys Res Commun. 2013 Aug 16;438(1):156-60. doi: 10.1016/j.bbrc.2013.07.045. Epub 2013 Jul 20. Biochem Biophys Res Commun. 2013. PMID: 23876313
To evaluate the molecular function of Mamo protein, we have investigated the binding of Mamo to chromatin and DNA sequences. Our data show that Mamo binds to chromatin and specific DNA sequences, particularly the polytene chromosomes of s …
To evaluate the molecular function of Mamo protein, we have investigated the binding of Mamo to chromatin and DNA seque …
Unorthodox PCNA Binding by Chromatin Assembly Factor 1.
Gopinathan Nair A, Rabas N, Lejon S, Homiski C, Osborne MJ, Cyr N, Sverzhinsky A, Melendy T, Pascal JM, Laue ED, Borden KLB, Omichinski JG, Verreault A. Gopinathan Nair A, et al. Int J Mol Sci. 2022 Sep 21;23(19):11099. doi: 10.3390/ijms231911099. Int J Mol Sci. 2022. PMID: 36232396 Free PMC article.
The eukaryotic DNA replication fork is a hub of enzymes that continuously act to synthesize DNA, propagate DNA methylation and other epigenetic marks, perform quality control, repair nascent DNA, and package this DNA into chromatin. ...Th …
The eukaryotic DNA replication fork is a hub of enzymes that continuously act to synthesize DNA, propagate DNA methylat …
36,545 results
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