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Chronic Brucellosis in Japan.
Kawakami N, Wakai Y, Saito K, Imaoka K. Kawakami N, et al. Intern Med. 2019;58(21):3179-3183. doi: 10.2169/internalmedicine.2961-19. Epub 2019 Nov 1. Intern Med. 2019. PMID: 31685787 Free PMC article.
We herein report the case of a 39-year-old Japanese woman with chronic human brucellosis, considered a Brucella canis infection, that persisted for 19 years. ...Even in non-endemic areas, chronic brucellosis is an important differential diagnosis in patients …
We herein report the case of a 39-year-old Japanese woman with chronic human brucellosis, considered a Brucella canis infectio …
Induction Murine Models of Chronic Fatigue Syndrome by Brucella abortus Antigen Injections: Is Anemia Induced or Not?
Moriya J, He Q, Uenishi H, Akazawa S, Yamakawa J, Kobayashi J, Ishigaki Y. Moriya J, et al. Biomed Res Int. 2015;2015:191489. doi: 10.1155/2015/191489. Epub 2015 Jun 11. Biomed Res Int. 2015. PMID: 26171388 Free PMC article.
To investigate whether Brucella abortus (BA) antigen injections lead to anemia, and to establish an appropriate Chronic Fatigue Syndrome (CFS) animal model by BA injections, 6 repeated injections of BA antigen were fulfilled every 2 weeks. ...
To investigate whether Brucella abortus (BA) antigen injections lead to anemia, and to establish an appropriate Chronic Fat
Epigallocatechin gallate ameliorates chronic fatigue syndrome in mice: behavioral and biochemical evidence.
Sachdeva AK, Kuhad A, Tiwari V, Chopra K. Sachdeva AK, et al. Behav Brain Res. 2009 Dec 28;205(2):414-20. doi: 10.1016/j.bbr.2009.07.020. Epub 2009 Jul 28. Behav Brain Res. 2009. PMID: 19643148
Chronic fatigue syndrome pathogenesis seems to be multifactorial and the possible involvement of immune system is supported. ...On 19th day, after lipopolysaccharide/Brucella abortus administration, the mice showed significant increase in immobility period, p
Chronic fatigue syndrome pathogenesis seems to be multifactorial and the possible involvement of immune system is supported. .
Modulation of antigen-induced chronic fatigue in mouse model of water immersion stress by naringin, a polyphenolic antioxidant.
Vij G, Gupta A, Chopra K. Vij G, et al. Fundam Clin Pharmacol. 2009 Jun;23(3):331-7. doi: 10.1111/j.1472-8206.2009.00675.x. Epub 2009 Mar 11. Fundam Clin Pharmacol. 2009. PMID: 19469804
There is little evidence stating the beneficial role of nutritional supplements in chronic fatigue syndrome. Based on this, this study was designed to evaluate the effect of naringin, a natural polyphenol, in a mouse model of immunologically-induced fatigue, …
There is little evidence stating the beneficial role of nutritional supplements in chronic fatigue syndrome. Based on this, th …
Curcumin, a polyphenolic antioxidant, attenuates chronic fatigue syndrome in murine water immersion stress model.
Gupta A, Vij G, Sharma S, Tirkey N, Rishi P, Chopra K. Gupta A, et al. Immunobiology. 2009;214(1):33-9. doi: 10.1016/j.imbio.2008.04.003. Epub 2008 Jun 17. Immunobiology. 2009. PMID: 19159825
Chronic fatigue syndrome, infection and oxidative stress are interrelated in epidemiological case studies. However, data demonstrating scientific validation of epidemiological claims regarding effectiveness of nutritional supplements for chronic fatigue
Chronic fatigue syndrome, infection and oxidative stress are interrelated in epidemiological case studies. However, data demon
Possible role of oxidative stress and immunological activation in mouse model of chronic fatigue syndrome and its attenuation by olive extract.
Gupta A, Vij G, Chopra K. Gupta A, et al. J Neuroimmunol. 2010 Sep 14;226(1-2):3-7. doi: 10.1016/j.jneuroim.2010.05.021. Epub 2010 May 26. J Neuroimmunol. 2010. PMID: 20537729
Scientific evidence highlighting the protective role of nutritional supplements in chronic fatigue syndrome is lacking. Based on these assumptions, the present study was designed to evaluate the effect of olive extract in a mouse model of immunologically-induced …
Scientific evidence highlighting the protective role of nutritional supplements in chronic fatigue syndrome is lacking. Based …
Mouse running activity is lowered by Brucella abortus treatment: a potential model to study chronic fatigue.
Ottenweller JE, Natelson BH, Gause WC, Carroll KK, Beldowicz D, Zhou XD, LaManca JJ. Ottenweller JE, et al. Physiol Behav. 1998 Mar;63(5):795-801. doi: 10.1016/s0031-9384(97)00539-8. Physiol Behav. 1998. PMID: 9618001
Chronic fatigue syndrome, which can occur after acute infection and last for years, is characterized by severe and persistent fatigue. Others have reported decreases in mouse running activity following infection and have suggested this may provide an animal m
Chronic fatigue syndrome, which can occur after acute infection and last for years, is characterized by severe and persistent
Chronic brucellosis and persistence of Brucella melitensis DNA.
Castaño MJ, Solera J. Castaño MJ, et al. J Clin Microbiol. 2009 Jul;47(7):2084-9. doi: 10.1128/JCM.02159-08. Epub 2009 May 6. J Clin Microbiol. 2009. PMID: 19420176 Free PMC article.
Such patients are defined as having chronic brucellosis. Since no objective laboratory methods exist to confirm the presence of chronic disease, these patients suffer delays in both diagnosis and treatment. ...Therefore, Q-PCR appears to be a useful method for ident …
Such patients are defined as having chronic brucellosis. Since no objective laboratory methods exist to confirm the presence of ch
Resveratrol improves hippocampal atrophy in chronic fatigue mice by enhancing neurogenesis and inhibiting apoptosis of granular cells.
Moriya J, Chen R, Yamakawa J, Sasaki K, Ishigaki Y, Takahashi T. Moriya J, et al. Biol Pharm Bull. 2011;34(3):354-9. doi: 10.1248/bpb.34.354. Biol Pharm Bull. 2011. PMID: 21372384 Free article.
Neuroimaging evidence showed structural and/or functional abnormalities existing in the central nervous system, especially the hippocampus, in chronic fatigue syndrome (CFS) patients. ...We established a chronic fatigue murine model by six repeated inj …
Neuroimaging evidence showed structural and/or functional abnormalities existing in the central nervous system, especially the hippocampus, …
Neuroinflammation, Oxidative Stress, and Neurogenesis in a Mouse Model of Chronic Fatigue Syndrome, and the Treatment with Kampo Medicine.
He Q, Sawada M, Yamasaki N, Akazawa S, Furuta H, Uenishi H, Meng X, Nakahashi T, Ishigaki Y, Moriya J. He Q, et al. Biol Pharm Bull. 2020;43(1):110-115. doi: 10.1248/bpb.b19-00616. Biol Pharm Bull. 2020. PMID: 31902915 Free article.
The diagnosis of chronic fatigue syndrome (CFS) is mainly symptom-based, and the etiology is still unclear. Here, we evaluated the pathological changes in the brain of a mouse model of CFS and studied the effects of Kampo medicine. A mouse model of CFS was establish …
The diagnosis of chronic fatigue syndrome (CFS) is mainly symptom-based, and the etiology is still unclear. Here, we evaluated …
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