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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1968 1
1969 1
1970 1
1971 1
1973 3
1975 2
1976 5
1977 6
1978 7
1979 12
1980 4
1981 6
1982 10
1983 17
1984 21
1985 25
1986 24
1987 20
1988 23
1989 34
1990 19
1991 30
1992 27
1993 28
1994 23
1995 48
1996 22
1997 35
1998 28
1999 42
2000 39
2001 45
2002 54
2003 49
2004 52
2005 75
2006 76
2007 81
2008 106
2009 100
2010 106
2011 97
2012 142
2013 132
2014 133
2015 121
2016 106
2017 112
2018 102
2019 119
2020 114
2021 52
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2,244 results
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Page 1
A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice.
Son H, Yang JH, Kim HJ, Lee DK. Son H, et al. J Vis Exp. 2019 May 15;(147). doi: 10.3791/59546. J Vis Exp. 2019. PMID: 31157777
Thus, in the present paper, we propose a mouse model of depression induced by movement restriction. Chronic mild stress (CMS) is a well-known technique to induce depressive-like behavior. However, it necessitates a complex procedure consisting of a combination of va …
Thus, in the present paper, we propose a mouse model of depression induced by movement restriction. Chronic mild stress (CMS) …
Xiaoyaosan improves depressive-like behavior in rats with chronic immobilization stress through modulation of the gut microbiota.
Zhu HZ, Liang YD, Ma QY, Hao WZ, Li XJ, Wu MS, Deng LJ, Li YM, Chen JX. Zhu HZ, et al. Biomed Pharmacother. 2019 Apr;112:108621. doi: 10.1016/j.biopha.2019.108621. Epub 2019 Feb 21. Biomed Pharmacother. 2019. PMID: 30798141 Free article.
., control, model, XYS, and fluoxetine). The latter three groups were subjected to 21 days of chronic restraint stress to produce the stress depression model. Rats in the XYS and fluoxetine groups received intragastric administration of XYS and fluoxetine, re …
., control, model, XYS, and fluoxetine). The latter three groups were subjected to 21 days of chronic restraint stress to prod …
Anti-oxidative effects of curcumin on immobilization-induced oxidative stress in rat brain, liver and kidney.
Samarghandian S, Azimi-Nezhad M, Farkhondeh T, Samini F. Samarghandian S, et al. Biomed Pharmacother. 2017 Mar;87:223-229. doi: 10.1016/j.biopha.2016.12.105. Epub 2017 Jan 3. Biomed Pharmacother. 2017. PMID: 28061405
The present study was designed to investigate the protective effects of CUR on restraint stress induced oxidative stress damage in the brain, liver and kidneys. For chronic restraint stress, rats were kept in the restrainers for 1h every day, for 21 co …
The present study was designed to investigate the protective effects of CUR on restraint stress induced oxidative stress damag …
Impact of chronic immobilization stress on parameters of colonic homeostasis in BALB/c mice.
Machorro-Rojas N, Sainz-Espuñes T, Godínez-Victoria M, Castañeda-Sánchez JI, Campos-Rodríguez R, Pacheco-Yepez J, Drago-Serrano ME. Machorro-Rojas N, et al. Mol Med Rep. 2019 Sep;20(3):2083-2090. doi: 10.3892/mmr.2019.10437. Epub 2019 Jun 27. Mol Med Rep. 2019. PMID: 31257542 Free PMC article.
The aim of the present study was to evaluate the effects of chronic immobilization stress on the colonic expression of various parameters of homeostasis. ...These results indicated that immobilization stress induced proinflammatory and potential …
The aim of the present study was to evaluate the effects of chronic immobilization stress on the colonic expression of …
Prevention of chronic immobilization stress-induced enhanced expression of glucocorticoid receptors in the prefrontal cortex by inactivation of basolateral amygdala.
Tripathi SJ, Chakraborty S, Srikumar BN, Raju TR, Shankaranarayana Rao BS. Tripathi SJ, et al. J Chem Neuroanat. 2019 Jan;95:134-145. doi: 10.1016/j.jchemneu.2017.12.006. Epub 2017 Dec 23. J Chem Neuroanat. 2019. PMID: 29277704
It is well established that BLA positively regulates the HPA axis and undergoes hypertrophy following chronic immobilization stress (CIS). However, it is not known whether inactivation of the BLA can modulate the stress-induced changes in the expressio …
It is well established that BLA positively regulates the HPA axis and undergoes hypertrophy following chronic immobilization
Hepatoprotective effect of limonene against chronic immobilization induced liver damage in rats.
Amini R, Asle-Rousta M, Aghazadeh S. Amini R, et al. Naunyn Schmiedebergs Arch Pharmacol. 2020 Nov;393(11):2053-2059. doi: 10.1007/s00210-020-01915-0. Epub 2020 Jun 8. Naunyn Schmiedebergs Arch Pharmacol. 2020. PMID: 32514601
In this study, we investigated the hepatoprotective effect of limonene (a monoterpene) in male rats exposed to chronic immobilization. Rats were exposed to immobilization stress (6 h/21 days) and received limonene (10 mg/kg, oral gavage) during this pe …
In this study, we investigated the hepatoprotective effect of limonene (a monoterpene) in male rats exposed to chronic immobilizat
Chronic immobilization stress alters aspects of emotionality and associative learning in the rat.
Wood GE, Norris EH, Waters E, Stoldt JT, McEwen BS. Wood GE, et al. Behav Neurosci. 2008 Apr;122(2):282-92. doi: 10.1037/0735-7044.122.2.282. Behav Neurosci. 2008. PMID: 18410168
Chronic stress significantly alters limbic neuroarchitecture and function, and potentiates emotionality in rats. ...Chronic immobilization stress (CIS) induces anxiety behavior and dendritic hypertrophy in the basolateral amygdala, which persist
Chronic stress significantly alters limbic neuroarchitecture and function, and potentiates emotionality in rats. ...Chronic
Inactivation of basolateral amygdala prevents chronic immobilization stress-induced memory impairment and associated changes in corticosterone levels.
Tripathi SJ, Chakraborty S, Srikumar BN, Raju TR, Shankaranarayana Rao BS. Tripathi SJ, et al. Neurobiol Learn Mem. 2017 Jul;142(Pt B):218-229. doi: 10.1016/j.nlm.2017.05.005. Epub 2017 May 8. Neurobiol Learn Mem. 2017. PMID: 28495605
Chronic stress causes detrimental effects on various forms of learning and memory. The basolateral amygdala (BLA) not only plays a crucial role in mediating certain forms of memory, but also in the modulation of the effects of stress. Chronic immobi
Chronic stress causes detrimental effects on various forms of learning and memory. The basolateral amygdala (BLA) not only pla
Chronic restraint stress induces serotonin transporter expression in the rat adrenal glands.
Shanker S, Saroj N, Cordova EJ, Jarillo-Luna RA, López-Sánchez P, Terrón JA. Shanker S, et al. Mol Cell Endocrinol. 2020 Dec 1;518:110935. doi: 10.1016/j.mce.2020.110935. Epub 2020 Jul 11. Mol Cell Endocrinol. 2020. PMID: 32659440
Chronic restraint stress (CRS) magnifies restraint-induced corticosterone secretion through a mechanism involving increased adrenocortical 5-HT content and turnover. ...Closely similar results were obtained in animals that received a 14-day chronic corticoste
Chronic restraint stress (CRS) magnifies restraint-induced corticosterone secretion through a mechanism involving increased ad
Chronic but not acute immobilization stress stably enhances hippocampal CA1 metabotropic glutamate receptor dependent Long-Term Depression.
Sengupta T, Das R, Chattarji S. Sengupta T, et al. Neurosci Lett. 2016 Oct 28;633:101-105. doi: 10.1016/j.neulet.2016.09.031. Epub 2016 Sep 20. Neurosci Lett. 2016. PMID: 27663134
However, the effect of chronic stress on mGluR dependent LTD has not been investigated. Moreover, whether stress leads to a transient modification LTD threshold or a more stable change in synaptic plasticity needs to be addressed. ...Acute stress i.e. …
However, the effect of chronic stress on mGluR dependent LTD has not been investigated. Moreover, whether stress leads …
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