Opioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysis.
Busse JW, Wang L, Kamaleldin M, Craigie S, Riva JJ, Montoya L, Mulla SM, Lopes LC, Vogel N, Chen E, Kirmayr K, De Oliveira K, Olivieri L, Kaushal A, Chaparro LE, Oyberman I, Agarwal A, Couban R, Tsoi L, Lam T, Vandvik PO, Hsu S, Bala MM, Schandelmaier S, Scheidecker A, Ebrahim S, Ashoorion V, Rehman Y, Hong PJ, Ross S, Johnston BC, Kunz R, Sun X, Buckley N, Sessler DI, Guyatt GH.
Busse JW, et al.
JAMA. 2018 Dec 18;320(23):2448-2460. doi: 10.1001/jama.2018.18472.
JAMA. 2018.
PMID: 30561481
Free PMC article.
IMPORTANCE: Harms and benefits of opioids for chronic noncancer pain remain unclear. OBJECTIVE: To systematically review randomized clinical trials (RCTs) of opioids for chronic noncancer pain. ...Of the included studies, there were 25 trials of neurop …
IMPORTANCE: Harms and benefits of opioids for chronic noncancer pain remain unclear. OBJECTIVE: To systematically review rando …