Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1980 1
1981 1
1983 1
1984 1
1994 1
1996 1
1997 6
1998 4
1999 5
2000 4
2001 16
2002 12
2003 18
2004 24
2005 26
2006 36
2007 50
2008 43
2009 50
2010 40
2011 48
2012 49
2013 48
2014 57
2015 68
2016 76
2017 74
2018 97
2019 126
2020 179
2021 197
2022 182
2023 157
2024 161
2025 190
2026 125

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

1,898 results

Results by year

Filters applied: . Clear all
Page 1
Medical Cannabis for Chronic Nonmalignant Pain Management.
Hameed M, Prasad S, Jain E, Dogrul BN, Al-Oleimat A, Pokhrel B, Chowdhury S, Co EL, Mitra S, Quinonez J, Ruxmohan S, Stein J. Hameed M, et al. Curr Pain Headache Rep. 2023 Apr;27(4):57-63. doi: 10.1007/s11916-023-01101-w. Epub 2023 Mar 10. Curr Pain Headache Rep. 2023. PMID: 36897501 Free PMC article. Review.
Few studies have found a limited relationship between chronic pain and medical cannabis use. A total of 77 articles were selected after a thorough screening process using PubMed and Google Scholar. This paper demonstrates that medical cannabis use provides adequate …
Few studies have found a limited relationship between chronic pain and medical cannabis use. A total of 77 articles were selec …
Clinical Practice Guidelines for Cannabis and Cannabinoid-Based Medicines in the Management of Chronic Pain and Co-Occurring Conditions.
Bell AD, MacCallum C, Margolese S, Walsh Z, Wright P, Daeninck PJ, Mandarino E, Lacasse G, Kaur Deol J, de Freitas L, St Pierre M, Belle-Isle L, Gagnon M, Bevan S, Sanchez T, Arlt S, Monahan-Ellison M, O'Hara J, Boivin M, Costiniuk C. Bell AD, et al. Cannabis Cannabinoid Res. 2024 Apr;9(2):669-687. doi: 10.1089/can.2021.0156. Epub 2023 Mar 27. Cannabis Cannabinoid Res. 2024. PMID: 36971587 Free PMC article.
Background: One in five individuals live with chronic pain globally, which often co-occurs with sleep problems, anxiety, depression, and substance use disorders. ...Aims: We present these clinical practice guidelines to help clinicians and patients navigate appropri …
Background: One in five individuals live with chronic pain globally, which often co-occurs with sleep problems, anxiety, depre …
Opioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysis.
Busse JW, Wang L, Kamaleldin M, Craigie S, Riva JJ, Montoya L, Mulla SM, Lopes LC, Vogel N, Chen E, Kirmayr K, De Oliveira K, Olivieri L, Kaushal A, Chaparro LE, Oyberman I, Agarwal A, Couban R, Tsoi L, Lam T, Vandvik PO, Hsu S, Bala MM, Schandelmaier S, Scheidecker A, Ebrahim S, Ashoorion V, Rehman Y, Hong PJ, Ross S, Johnston BC, Kunz R, Sun X, Buckley N, Sessler DI, Guyatt GH. Busse JW, et al. JAMA. 2018 Dec 18;320(23):2448-2460. doi: 10.1001/jama.2018.18472. JAMA. 2018. PMID: 30561481 Free PMC article.
IMPORTANCE: Harms and benefits of opioids for chronic noncancer pain remain unclear. OBJECTIVE: To systematically review randomized clinical trials (RCTs) of opioids for chronic noncancer pain. ...Of the included studies, there were 25 trials of neurop …
IMPORTANCE: Harms and benefits of opioids for chronic noncancer pain remain unclear. OBJECTIVE: To systematically review rando …
Cannabis-Based Products for Chronic Pain : A Systematic Review.
McDonagh MS, Morasco BJ, Wagner J, Ahmed AY, Fu R, Kansagara D, Chou R. McDonagh MS, et al. Ann Intern Med. 2022 Aug;175(8):1143-1153. doi: 10.7326/M21-4520. Epub 2022 Jun 7. Ann Intern Med. 2022. PMID: 35667066 Free article.
BACKGROUND: Contemporary data are needed about the utility of cannabinoids in chronic pain. PURPOSE: To evaluate the benefits and harms of cannabinoids for chronic pain. ...STUDY SELECTION: English-language, randomized, placebo-controlled …
BACKGROUND: Contemporary data are needed about the utility of cannabinoids in chronic pain. PURPOSE: To evaluate the be …
Medical cannabis or cannabinoids for chronic non-cancer and cancer related pain: a systematic review and meta-analysis of randomised clinical trials.
Wang L, Hong PJ, May C, Rehman Y, Oparin Y, Hong CJ, Hong BY, AminiLari M, Gallo L, Kaushal A, Craigie S, Couban RJ, Kum E, Shanthanna H, Price I, Upadhye S, Ware MA, Campbell F, Buchbinder R, Agoritsas T, Busse JW. Wang L, et al. BMJ. 2021 Sep 8;374:n1034. doi: 10.1136/bmj.n1034. BMJ. 2021. PMID: 34497047
OBJECTIVE: To determine the benefits and harms of medical cannabis and cannabinoids for chronic pain. DESIGN: Systematic review and meta-analysis. DATA SOURCES: MEDLINE, EMBASE, AMED, PsycInfo, CENTRAL, CINAHL, PubMed, Web of Science, Cannabis-Med, Epistemoni …
OBJECTIVE: To determine the benefits and harms of medical cannabis and cannabinoids for chronic pain. DESIGN: Systemati …
Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic Review.
Mohammed SYM, Leis K, Mercado RE, Castillo MMS, Miranda KJ, Carandang RR. Mohammed SYM, et al. Pain Manag Nurs. 2024 Apr;25(2):e76-e86. doi: 10.1016/j.pmn.2023.10.002. Epub 2023 Nov 11. Pain Manag Nurs. 2024. PMID: 37953193
Therefore, this systematic review aimed to synthesize evidence on the effectiveness of CBD in chronic pain management. DESIGN: A systematic review of literature utilizing PRISMA 2020 guidelines. ...More studies with robust study designs are warranted to evaluate CBD …
Therefore, this systematic review aimed to synthesize evidence on the effectiveness of CBD in chronic pain management. DESIGN: …
Cannabis-based medicines for chronic neuropathic pain in adults.
Mücke M, Phillips T, Radbruch L, Petzke F, Häuser W. Mücke M, et al. Cochrane Database Syst Rev. 2018 Mar 7;3(3):CD012182. doi: 10.1002/14651858.CD012182.pub2. Cochrane Database Syst Rev. 2018. Update in: Cochrane Database Syst Rev. 2026 Jan 19;1:CD012182. doi: 10.1002/14651858.CD012182.pub3. PMID: 29513392 Free PMC article. Updated.
BACKGROUND: This review is one of a series on drugs used to treat chronic neuropathic pain. Estimates of the population prevalence of chronic pain with neuropathic components range between 6% and 10%. ...There is a need to explore other treatment optio …
BACKGROUND: This review is one of a series on drugs used to treat chronic neuropathic pain. Estimates of the population preval …
Cannabis-Based Products for Chronic Pain : An Updated Systematic Review.
Chou R, Fu R, Ahmed AY, Morasco BJ. Chou R, et al. Ann Intern Med. 2026 Feb;179(2):230-241. doi: 10.7326/ANNALS-25-03152. Epub 2025 Dec 23. Ann Intern Med. 2026. PMID: 41429020
BACKGROUND: Benefits and harms of cannabinoids for chronic pain are uncertain. PURPOSE: To update an evidence synthesis on cannabinoids for chronic pain. ...CONCLUSION: Comparable and high THC-to-CBD ratio cannabinoid products may …
BACKGROUND: Benefits and harms of cannabinoids for chronic pain are uncertain. PURPOSE: To update an evidence synthesis …
Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies.
Solmi M, De Toffol M, Kim JY, Choi MJ, Stubbs B, Thompson T, Firth J, Miola A, Croatto G, Baggio F, Michelon S, Ballan L, Gerdle B, Monaco F, Simonato P, Scocco P, Ricca V, Castellini G, Fornaro M, Murru A, Vieta E, Fusar-Poli P, Barbui C, Ioannidis JPA, Carvalho AF, Radua J, Correll CU, Cortese S, Murray RM, Castle D, Shin JI, Dragioti E. Solmi M, et al. BMJ. 2023 Aug 30;382:e072348. doi: 10.1136/bmj-2022-072348. BMJ. 2023. PMID: 37648266 Free PMC article.
Cannabidiol improved 50% reduction of seizures (0.59 (0.38 to 0.92)) and seizure events (0.59 (0.36 to 0.96)) (GRADE=high), but increased pneumonia, gastrointestinal adverse events, and somnolence (GRADE=moderate). For chronic pain, cannabis based medicines or ca
Cannabidiol improved 50% reduction of seizures (0.59 (0.38 to 0.92)) and seizure events (0.59 (0.36 to 0.96)) (GRADE=high), but increased pn …
Cannabinoids for Medical Use: A Systematic Review and Meta-analysis.
Whiting PF, Wolff RF, Deshpande S, Di Nisio M, Duffy S, Hernandez AV, Keurentjes JC, Lang S, Misso K, Ryder S, Schmidlkofer S, Westwood M, Kleijnen J. Whiting PF, et al. JAMA. 2015 Jun 23-30;313(24):2456-73. doi: 10.1001/jama.2015.6358. JAMA. 2015. PMID: 26103030
OBJECTIVE: To conduct a systematic review of the benefits and adverse events (AEs) of cannabinoids. DATA SOURCES: Twenty-eight databases from inception to April 2015. STUDY SELECTION: Randomized clinical trials of cannabinoids for the following indications: nausea a …
OBJECTIVE: To conduct a systematic review of the benefits and adverse events (AEs) of cannabinoids. DATA SOURCES: Twenty-eight databa …
1,898 results