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80 results

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Page 1
BTK signaling-a crucial link in the pathophysiology of chronic spontaneous urticaria.
Bernstein JA, Maurer M, Saini SS. Bernstein JA, et al. J Allergy Clin Immunol. 2024 May;153(5):1229-1240. doi: 10.1016/j.jaci.2023.12.008. Epub 2023 Dec 21. J Allergy Clin Immunol. 2024. PMID: 38141832 Free article. Review.
Chronic spontaneous urticaria (CSU) is an inflammatory skin disorder that manifests with itchy wheals, angioedema, or both for more than 6 weeks. Mast cells and basophils are the key pathogenic drivers of CSU; their activation results in histamine …
Chronic spontaneous urticaria (CSU) is an inflammatory skin disorder that manifests with itchy wheals, angioedema, or both for …
Chronic spontaneous urticaria and chronic inducible urticaria.
Lee R, Bernstein JA. Lee R, et al. J Allergy Clin Immunol. 2025 Sep;156(3):546-556. doi: 10.1016/j.jaci.2025.05.019. Epub 2025 May 30. J Allergy Clin Immunol. 2025. PMID: 40451490 Free article. Review.
As many as 7% to 30% of patients with chronic urticaria can have both types. Mast cells are the core effector cells involved in the pathogenesis of chronic urticaria. ...However, the pathophysiology of chronic urti …
As many as 7% to 30% of patients with chronic urticaria can have both types. Mast cells are the core effector …
Cold urticaria - What we know and what we do not know.
Maltseva N, Borzova E, Fomina D, Bizjak M, Terhorst-Molawi D, Košnik M, Kulthanan K, Meshkova R, Thomsen SF, Maurer M; COLD-CE Steering Committee. Maltseva N, et al. Allergy. 2021 Apr;76(4):1077-1094. doi: 10.1111/all.14674. Epub 2020 Dec 24. Allergy. 2021. PMID: 33249577 Review.
Cold urticaria (ColdU) is a common form of chronic inducible urticaria characterized by the development of wheals, angioedema or both in response to cold exposure. Recent research and guideline updates have advanced our understanding and management of ColdU. …
Cold urticaria (ColdU) is a common form of chronic inducible urticaria characterized by the development of wheals, angi …
Angioedema.
Kaplan AP, Greaves MW. Kaplan AP, et al. J Am Acad Dermatol. 2005 Sep;53(3):373-88; quiz 389-92. doi: 10.1016/j.jaad.2004.09.032. J Am Acad Dermatol. 2005. PMID: 16112343 Review.
Although clinically similar, angioedema can be caused by either mast cell degranulation or activation of kinin formation. In the former category, allergic and nonsteroidal anti-inflammatory drug-induced angioedema are frequently accompanied by urticaria. ...I …
Although clinically similar, angioedema can be caused by either mast cell degranulation or activation of kinin formation. In t …
Pathogenesis of Chronic Spontaneous Urticaria With or Without Angioedema.
Saini SS, Asero R, Cugno M, Park HS, Oliver ET. Saini SS, et al. J Allergy Clin Immunol Pract. 2025 Sep;13(9):2221-2228. doi: 10.1016/j.jaip.2025.07.025. Epub 2025 Jul 26. J Allergy Clin Immunol Pract. 2025. PMID: 40721160 Review.
Histopathologic analysis reveals skin mast cell degranulation and a perivascular infiltrate composed of lymphocytes, eosinophils, neutrophils, and basophils. Mast cells and basophils are key effector cells in the pathogenesis and severity of CSU …
Histopathologic analysis reveals skin mast cell degranulation and a perivascular infiltrate composed of lymphocytes, eosinophi …
Histaminergic Angioedema.
Busse PJ, Smith T. Busse PJ, et al. Immunol Allergy Clin North Am. 2017 Aug;37(3):467-481. doi: 10.1016/j.iac.2017.03.001. Epub 2017 May 13. Immunol Allergy Clin North Am. 2017. PMID: 28687103 Review.
It is classified as either acute (lasting <6 weeks) or chronic (symptoms >6 weeks). It is further classified into angioedema presenting with or without urticaria. Some patients with acute angioedema may have disease that becomes chronic. Mast …
It is classified as either acute (lasting <6 weeks) or chronic (symptoms >6 weeks). It is further classified into angioedema pr …
Urticaria.
Sussman GL. Sussman GL. J Cutan Med Surg. 2000 Apr;4(2):94-5. doi: 10.1177/120347540000400210. J Cutan Med Surg. 2000. PMID: 11179932 No abstract available.
Pathophysiology of urticaria.
Hennino A, Bérard F, Guillot I, Saad N, Rozières A, Nicolas JF. Hennino A, et al. Clin Rev Allergy Immunol. 2006 Feb;30(1):3-11. doi: 10.1385/CRIAI:30:1:003. Clin Rev Allergy Immunol. 2006. PMID: 16461989 Review.
It is a common practice to distinguish immunological and nonimmunological urticaria. Immunological urticaria is a hypersensitivity reaction mediated by antibodies and/or T-cells that results in mast cell activation. ...These auto-immune urticari …
It is a common practice to distinguish immunological and nonimmunological urticaria. Immunological urticaria is a hypersensiti …
Pathophysiology of chronic urticaria.
Brodell LA, Beck LA, Saini SS. Brodell LA, et al. Ann Allergy Asthma Immunol. 2008 Apr;100(4):291-7; quiz 297-9, 322. doi: 10.1016/S1081-1206(10)60588-1. Ann Allergy Asthma Immunol. 2008. PMID: 18450112 Review.
OBJECTIVE: To review the literature on the pathogenesis of chronic urticaria (excluding physical urticaria). DATA SOURCES: PubMed was searched using the keywords urticaria and either chronic or autoimmune or pathogenesis for articles published f …
OBJECTIVE: To review the literature on the pathogenesis of chronic urticaria (excluding physical urticaria). DATA SOURC …
Chronic urticaria: pathophysiology and treatment approaches.
Tharp MD. Tharp MD. J Allergy Clin Immunol. 1996 Dec;98(6 Pt 3):S325-30. J Allergy Clin Immunol. 1996. PMID: 8977544 Review.
Urticaria, a cutaneous reaction pattern, varies clinically and histopathologically. The origin of acute urticaria can be detected in some cases; in patients with chronic urticaria, however, the cause is rarely identified. Thus, most patients with ch …
Urticaria, a cutaneous reaction pattern, varies clinically and histopathologically. The origin of acute urticaria can be detec …
80 results