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Beyond the itch: the complex interplay of immune, neurological, and psychological factors in chronic urticaria.
Yang S, Chen L, Zhang H, Song Y, Wang W, Hu Z, Wang S, Huang L, Wang Y, Wu S, Chen R, Liang F. Yang S, et al. J Neuroinflammation. 2025 Mar 11;22(1):75. doi: 10.1186/s12974-025-03397-4. J Neuroinflammation. 2025. PMID: 40069822 Free PMC article. Review.
Chronic urticaria (CU) arises from a multifaceted interplay of immunological, neurological, and psychological components. ...Psychological factors such as depression, anxiety, and stress exacerbate CU symptoms and diminish quality of life. These factors disru …
Chronic urticaria (CU) arises from a multifaceted interplay of immunological, neurological, and psychological components. ...P …
Cutaneous neuropeptides: the missing link between psychological stress and chronic inflammatory skin disease?
Keller JJ. Keller JJ. Arch Dermatol Res. 2023 Sep;315(7):1875-1881. doi: 10.1007/s00403-023-02542-4. Epub 2023 Jan 26. Arch Dermatol Res. 2023. PMID: 36700961 Review.
A "brain-skin" connection has been long been observed between chronic stress and chronic inflammatory skin disease including urticaria, psoriasis, atopic dermatitis, and prurigo nodularis. The relationship appears to be bidirectional. Chronic ps …
A "brain-skin" connection has been long been observed between chronic stress and chronic inflammatory skin disease incl …
Chronic idiopathic urticaria and post-traumatic stress disorder (PTSD): an under-recognized comorbidity.
Gupta MA, Gupta AK. Gupta MA, et al. Clin Dermatol. 2012 May-Jun;30(3):351-4. doi: 10.1016/j.clindermatol.2012.01.012. Clin Dermatol. 2012. PMID: 22507051
A large body of literature supports the role of psychologic stress in urticaria; however, the comorbidity between chronic idiopathic urticaria (CIU) and post-traumatic stress disorder (PTSD), a classic stress-mediated syndrome, has receiv …
A large body of literature supports the role of psychologic stress in urticaria; however, the comorbidity between chronic …
Use of antiepileptic mood stabilizers in dermatology.
Gupta MA, Pur DR, Vujcic B, Gupta AK. Gupta MA, et al. Clin Dermatol. 2018 Nov-Dec;36(6):756-764. doi: 10.1016/j.clindermatol.2018.08.005. Epub 2018 Aug 16. Clin Dermatol. 2018. PMID: 30446200 Review.
The AEDs may be effective in the management of (1) chronic pruritus, including pruritus due systemic disease, including uremia, neuropathic pain, neuropathic pruritus, and complex cutaneous sensory syndromes, especially where central nervous system (CNS) sens …
The AEDs may be effective in the management of (1) chronic pruritus, including pruritus due systemic disease, including uremia, neuro …
Efficacy and safety of Korean red ginseng for cold hypersensitivity in the hands and feet: a randomized, double-blind, placebo-controlled trial.
Park KS, Park KI, Kim JW, Yun YJ, Kim SH, Lee CH, Park JW, Lee JM. Park KS, et al. J Ethnopharmacol. 2014 Dec 2;158 Pt A:25-32. doi: 10.1016/j.jep.2014.09.028. Epub 2014 Oct 8. J Ethnopharmacol. 2014. PMID: 25284751 Clinical Trial.
The secondary outcome measures included change in skin temperature of the feet, visual analog scale (VAS) scores of CHHF severity, recovered temperature (RT) of the hands after cold stress test, distal-dorsal difference (DDD) in temperature of the hands, power variables of …
The secondary outcome measures included change in skin temperature of the feet, visual analog scale (VAS) scores of CHHF severity, recovered …
The Neuropsychological Dimensions to Pathogenesis of Chronic Spontaneous Urticaria Beyond Autoallergy - A Brief Narrative Review.
Kumaran MS, Kaur S, Parsad D, Narang T. Kumaran MS, et al. Indian Dermatol Online J. 2026 Jan 1;17(1):3-9. doi: 10.4103/idoj.idoj_415_25. Epub 2025 Dec 26. Indian Dermatol Online J. 2026. PMID: 41450013 Free PMC article.
Chronic spontaneous urticaria (CSU) is a burdensome dermatological condition with a complex, multifactorial pathogenesis involving intricate immune, neurological, and psychological interactions. ...This review examines the neuroimmune contributions to CSU pathogenes …
Chronic spontaneous urticaria (CSU) is a burdensome dermatological condition with a complex, multifactorial pathogenesis invol …