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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 2
1985 3
1986 11
1987 26
1988 17
1989 54
1990 34
1991 40
1992 39
1993 49
1994 40
1995 45
1996 38
1997 40
1998 45
1999 53
2000 35
2001 28
2002 33
2003 41
2004 40
2005 34
2006 38
2007 27
2008 34
2009 32
2010 26
2011 32
2012 39
2013 40
2014 22
2015 24
2016 30
2017 37
2018 45
2019 35
2020 29
2021 28
2022 31
2023 26
2024 13

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1,266 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients: a multicentre randomised clinical trial.
Ewoldt TMJ, Abdulla A, Rietdijk WJR, Muller AE, de Winter BCM, Hunfeld NGM, Purmer IM, van Vliet P, Wils EJ, Haringman J, Draisma A, Rijpstra TA, Karakus A, Gommers D, Endeman H, Koch BCP. Ewoldt TMJ, et al. Intensive Care Med. 2022 Dec;48(12):1760-1771. doi: 10.1007/s00134-022-06921-9. Epub 2022 Nov 9. Intensive Care Med. 2022. PMID: 36350354 Free PMC article. Clinical Trial.
PURPOSE: Individualising drug dosing using model-informed precision dosing (MIPD) of beta-lactam antibiotics and ciprofloxacin has been proposed as an alternative to standard dosing to optimise antibiotic efficacy in critically ill patients. ...CONCLUSIONS: We could not sh …
PURPOSE: Individualising drug dosing using model-informed precision dosing (MIPD) of beta-lactam antibiotics and ciprofloxacin has be …
Randomized Trial of Ciprofloxacin Doxycycline and Hydroxychloroquine Versus Budesonide in Active Crohn's Disease.
Rhodes JM, Subramanian S, Flanagan PK, Horgan GW, Martin K, Mansfield J, Parkes M, Hart A, Dallal H, Iqbal T, Butterworth J, Culshaw K, Probert C. Rhodes JM, et al. Dig Dis Sci. 2021 Aug;66(8):2700-2711. doi: 10.1007/s10620-020-06477-y. Epub 2020 Jul 17. Dig Dis Sci. 2021. PMID: 32681228 Clinical Trial.
METHODS: Adults with moderately active disease (CDAI > 220-450 plus C reactive protein 5 mg/l and/or fecal calprotectin > 250 mug/g) were randomized to receive (open-label) oral budesonide (Entocort CR 9 mg/day 8 weeks, 6 mg/day 2 weeks, 3 mg/day 2 weeks) or oral ciprofl
METHODS: Adults with moderately active disease (CDAI > 220-450 plus C reactive protein 5 mg/l and/or fecal calprotectin > 250 mug/g) w …
Sulopenem or Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infections in Women: A Phase 3, Randomized Trial.
Dunne MW, Aronin SI, Das AF, Akinapelli K, Zelasky MT, Puttagunta S, Boucher HW. Dunne MW, et al. Clin Infect Dis. 2023 Jan 6;76(1):66-77. doi: 10.1093/cid/ciac738. Clin Infect Dis. 2023. PMID: 36069202 Free PMC article. Clinical Trial.
In patients with ciprofloxacin-nonsusceptible baseline pathogens, sulopenem was compared for superiority over ciprofloxacin; in patients with ciprofloxacin-susceptible pathogens, the agents were compared for noninferiority. ...Sulopenem was not noninferior in …
In patients with ciprofloxacin-nonsusceptible baseline pathogens, sulopenem was compared for superiority over ciprofloxacin; i …
Ciprofloxacin/metronidazole versus beta-lactam-based treatment of intra-abdominal infections: a meta-analysis of comparative trials.
Matthaiou DK, Peppas G, Bliziotis IA, Falagas ME. Matthaiou DK, et al. Int J Antimicrob Agents. 2006 Sep;28(3):159-65. doi: 10.1016/j.ijantimicag.2006.04.005. Epub 2006 Aug 8. Int J Antimicrob Agents. 2006. PMID: 16899353 Review.
Thus, we sought to review the evidence from available comparative clinical trials studying ciprofloxacin/metronidazole versus broad-spectrum beta-lactam-based regimens in the treatment of intra-abdominal infections. ...There was a statistically significant difference betwe …
Thus, we sought to review the evidence from available comparative clinical trials studying ciprofloxacin/metronidazole versus broad-s …
Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial.
Drekonja DM, Trautner B, Amundson C, Kuskowski M, Johnson JR. Drekonja DM, et al. JAMA. 2021 Jul 27;326(4):324-331. doi: 10.1001/jama.2021.9899. JAMA. 2021. PMID: 34313686 Free PMC article. Clinical Trial.
OBJECTIVE: To determine whether 7 days of treatment is noninferior to 14 days when using ciprofloxacin or trimethoprim/sulfamethoxazole to treat urinary tract infection (UTI) in afebrile men. ...The findings support the use of a 7-day course of ciprofloxacin or trim …
OBJECTIVE: To determine whether 7 days of treatment is noninferior to 14 days when using ciprofloxacin or trimethoprim/sulfamethoxazo …
On ciprofloxacin concentration in chronic rhinosinusitis.
Gameiro Dos Santos J, Figueirinhas R, Liberal JP, Almeida JC, Sousa J, Falcão A, Vicente C, Paço J, Sousa CA. Gameiro Dos Santos J, et al. Acta Otorrinolaringol Esp (Engl Ed). 2018 Jan-Feb;69(1):35-41. doi: 10.1016/j.otorri.2017.06.008. Epub 2017 Aug 30. Acta Otorrinolaringol Esp (Engl Ed). 2018. PMID: 28859993 Clinical Trial. English, Spanish.
The plasma and mucosal ciprofloxacin concentrations were assayed with high performance liquid chromatography (HPLC) with fluorescence detection (FD). RESULTS: The oral ciprofloxacin achieved better mucosal concentrations but had a significant plasmatic expression in …
The plasma and mucosal ciprofloxacin concentrations were assayed with high performance liquid chromatography (HPLC) with fluorescence …
Efficacy and Safety of Ciprofloxacin Plus Fluocinolone Acetonide Among Patients With Acute Otitis Externa: A Randomized Clinical Trial.
Chu L, Acosta AM, Aazami H, Dennis P, De Valle O, Ehmer D Jr, Hedrick JA, Ansley JF. Chu L, et al. JAMA Netw Open. 2022 Jul 1;5(7):e2221699. doi: 10.1001/jamanetworkopen.2022.21699. JAMA Netw Open. 2022. PMID: 35834251 Free PMC article. Clinical Trial.
IMPORTANCE: Ciprofloxacin, 0.3%, plus fluocinolone acetonide, 0.025%, otic solution seems to be efficacious and safe in treating acute otitis externa (AOE) compared with ciprofloxacin, 0.3%, or fluocinolone acetonide, 0.025%, otic solution alone. OBJECTIVE: To evalu …
IMPORTANCE: Ciprofloxacin, 0.3%, plus fluocinolone acetonide, 0.025%, otic solution seems to be efficacious and safe in treating acut …
[Efficacy and safety of ciprofloxacin treatment in urinary tract infections (UTIs) in adults: a systematic review with meta-analysis].
Gutiérrez-Castrellón P, Díaz-García L, de Colsa-Ranero A, Cuevas-Alpuche J, Jiménez-Escobar I. Gutiérrez-Castrellón P, et al. Gac Med Mex. 2015 Mar-Apr;151(2):225-44. Gac Med Mex. 2015. PMID: 25946534 Free article. Review. Spanish.
OBJECTIVES AND DESIGN: A systematic review with meta-analysis of randomized controlled trials (RGT) on the efficacy and safety of ciprofloxacin in the treatment of acute or complicated urinary tract infections in adults. ...The percentage of bacterial resistance was simila …
OBJECTIVES AND DESIGN: A systematic review with meta-analysis of randomized controlled trials (RGT) on the efficacy and safety of ciprofl
Effect of ciprofloxacin vs levofloxacin on QTc-interval and dysglycemia in diabetic and non-diabetic patients.
Saad NA, Elberry AA, Samy Matar H, Hussein RRS. Saad NA, et al. Int J Clin Pract. 2021 May;75(5):e14072. doi: 10.1111/ijcp.14072. Epub 2021 Feb 12. Int J Clin Pract. 2021. PMID: 33559294 Clinical Trial.
The relative risk for dysglycemia with levofloxacin was 2.28 and 1.39 times more than ciprofloxacin in diabetic and non-diabetic patients, respectively. CONCLUSION: The present study showed that the risk for QTc prolongation and hyperglycemia was greater with levofloxacin …
The relative risk for dysglycemia with levofloxacin was 2.28 and 1.39 times more than ciprofloxacin in diabetic and non-diabetic pati …
Sulopenem for the Treatment of Complicated Urinary Tract Infections Including Pyelonephritis: A Phase 3, Randomized Trial.
Dunne MW, Aronin SI, Das AF, Akinapelli K, Breen J, Zelasky MT, Puttagunta S. Dunne MW, et al. Clin Infect Dis. 2023 Jan 6;76(1):78-88. doi: 10.1093/cid/ciac704. Clin Infect Dis. 2023. PMID: 36068705 Free PMC article. Clinical Trial.
METHODS: Hospitalized adults with pyuria, bacteriuria, and signs and symptoms of complicated urinary tract infection (cUTI) were randomized to 5 days of IV sulopenem followed by oral sulopenem etzadroxil/probenecid or 5 days of IV ertapenem followed by oral ciprofloxacin o …
METHODS: Hospitalized adults with pyuria, bacteriuria, and signs and symptoms of complicated urinary tract infection (cUTI) were randomized …
1,266 results