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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1952 4
1953 1
1955 1
1956 1
1959 4
1960 1
1961 2
1964 3
1972 1
1973 14
1974 26
1975 37
1976 41
1977 49
1978 104
1979 215
1980 185
1981 292
1982 416
1983 477
1984 673
1985 903
1986 939
1987 953
1988 1064
1989 1273
1990 1397
1991 1346
1992 1448
1993 1531
1994 1497
1995 1520
1996 1595
1997 1634
1998 1591
1999 1734
2000 1811
2001 1778
2002 1926
2003 1918
2004 2014
2005 2166
2006 2352
2007 2340
2008 2363
2009 2516
2010 2813
2011 3032
2012 3300
2013 3457
2014 3649
2015 3828
2016 3899
2017 4012
2018 3997
2019 4103
2020 4381
2021 4458
2022 4227
2023 458
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Search Results

86,124 results
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Page 1
Cisplatin in cancer therapy: molecular mechanisms of action.
Dasari S, Tchounwou PB. Dasari S, et al. Eur J Pharmacol. 2014 Oct 5;740:364-78. doi: 10.1016/j.ejphar.2014.07.025. Epub 2014 Jul 21. Eur J Pharmacol. 2014. PMID: 25058905 Free PMC article. Review.
Cisplatin, cisplatinum, or cis-diamminedichloroplatinum (II), is a well-known chemotherapeutic drug. ...This comprehensive review highlights the physicochemical properties of cisplatin and related platinum-based drugs, and discusses its uses (either alone or in comb …
Cisplatin, cisplatinum, or cis-diamminedichloroplatinum (II), is a well-known chemotherapeutic drug. ...This comprehensive review hig …
Cisplatin: The first metal based anticancer drug.
Ghosh S. Ghosh S. Bioorg Chem. 2019 Jul;88:102925. doi: 10.1016/j.bioorg.2019.102925. Epub 2019 Apr 11. Bioorg Chem. 2019. PMID: 31003078 Review.
However, side effects and drug resistance are the two inherent challenges of cisplatin which limit its application and effectiveness. Reduction of drug accumulation inside cancer cells, inactivation of drug by reacting with glutathione and metallothioneins and faster repai …
However, side effects and drug resistance are the two inherent challenges of cisplatin which limit its application and effectiveness. …
Advances in Toxicological Research of the Anticancer Drug Cisplatin.
Qi L, Luo Q, Zhang Y, Jia F, Zhao Y, Wang F. Qi L, et al. Chem Res Toxicol. 2019 Aug 19;32(8):1469-1486. doi: 10.1021/acs.chemrestox.9b00204. Epub 2019 Aug 5. Chem Res Toxicol. 2019. PMID: 31353895 Review.
Unfortunately, the clinical use of cisplatin is limited by its severe, dose-dependent toxic side effects. ...This review summarizes and reviews the updated advances in the toxicological research of cisplatin. We anticipate to provide insights into the understanding …
Unfortunately, the clinical use of cisplatin is limited by its severe, dose-dependent toxic side effects. ...This review summarizes a …
Pharmacological Effects of Cisplatin Combination with Natural Products in Cancer Chemotherapy.
Dasari S, Njiki S, Mbemi A, Yedjou CG, Tchounwou PB. Dasari S, et al. Int J Mol Sci. 2022 Jan 28;23(3):1532. doi: 10.3390/ijms23031532. Int J Mol Sci. 2022. PMID: 35163459 Free PMC article. Review.
Cisplatin and other platinum-based drugs, such as carboplatin, ormaplatin, and oxaliplatin, have been widely used to treat a multitude of human cancers. ...Furthermore, natural products protect against cisplatin-induced organ toxicity by modulating several gene tran …
Cisplatin and other platinum-based drugs, such as carboplatin, ormaplatin, and oxaliplatin, have been widely used to treat a multitud …
Is Autophagy Always a Barrier to Cisplatin Therapy?
Xu J, Gewirtz DA. Xu J, et al. Biomolecules. 2022 Mar 17;12(3):463. doi: 10.3390/biom12030463. Biomolecules. 2022. PMID: 35327655 Free PMC article. Review.
Cisplatin has long been a first-line chemotherapeutic agent in the treatment of cancer, largely for solid tumors. ...In this review and commentary, we introduce four mechanisms of resistance to cisplatin followed by a discussion of the factors that affect the role o …
Cisplatin has long been a first-line chemotherapeutic agent in the treatment of cancer, largely for solid tumors. ...In this review a …
Cisplatin.
[No authors listed] [No authors listed] Lancet. 1982 Feb 13;1(8268):374-5. Lancet. 1982. PMID: 6120354 No abstract available.
Cisplatin.
Reed E. Reed E. Cancer Chemother Biol Response Modif. 1992;13:83-90. Cancer Chemother Biol Response Modif. 1992. PMID: 1389927 Review. No abstract available.
[Cisplatin or carboplatin, that is the question].
Moncharmont C, Auberdiac P, Mélis A, Afqir S, Pacaut C, Chargari C, Merrouche Y, Magné N. Moncharmont C, et al. Bull Cancer. 2011 Feb;98(2):164-75. doi: 10.1684/bdc.2011.1307. Bull Cancer. 2011. PMID: 21382796 Free article. Review. French.
This paper aims at reviewing and comparing the current indications in terms of efficacy and toxicity of cisplatin and carboplatin. Although cisplatin has demonstrated its superiority over carboplatin for treatment of lung cancers and germ-cell tumors, the tolerance …
This paper aims at reviewing and comparing the current indications in terms of efficacy and toxicity of cisplatin and carboplatin. Al …
Cisplatin induced arrhythmia; electrolyte imbalance or disturbance of the SA node?
Oun R, Rowan E. Oun R, et al. Eur J Pharmacol. 2017 Sep 15;811:125-128. doi: 10.1016/j.ejphar.2017.05.063. Epub 2017 Jun 8. Eur J Pharmacol. 2017. PMID: 28599874 Free article. Review.
Cisplatin's side effects primarily include nephrotoxicity, gastrointestinal toxicity, neurotoxicity and ototoxicity. Cardiotoxicity is generally not defined as a side effect of cisplatin. However, over the past decade there has been a surge in the amount of c …
Cisplatin's side effects primarily include nephrotoxicity, gastrointestinal toxicity, neurotoxicity and ototoxicity. Cardiotox …
[50th anniversary of cisplatin].
Rancoule C, Guy JB, Vallard A, Ben Mrad M, Rehailia A, Magné N. Rancoule C, et al. Bull Cancer. 2017 Feb;104(2):167-176. doi: 10.1016/j.bulcan.2016.11.011. Epub 2016 Dec 15. Bull Cancer. 2017. PMID: 27989629 Review. French.
We have just celebrated the 50th anniversary of cisplatin cytotoxic potential discovery. It is time to take stock and it seems mainly positive. ...Indeed many research axes are in the news. New platinum salts agents are tested, new cisplatin formulations are develop …
We have just celebrated the 50th anniversary of cisplatin cytotoxic potential discovery. It is time to take stock and it seems mainly …
86,124 results
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