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Efficacy and Safety of Cissus quadrangularis L. in Clinical Use: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Sawangjit R, Puttarak P, Saokaew S, Chaiyakunapruk N. Sawangjit R, et al. Phytother Res. 2017 Apr;31(4):555-567. doi: 10.1002/ptr.5783. Epub 2017 Feb 6. Phytother Res. 2017. PMID: 28165166 Review.
Cissus quadrangularis L. (Cissus) is a medicinal plant commonly used for centuries for various conditions, but lacks critical appraisal of its clinical effects. ...Quality of evidence based on Grades of Recommendations Assessment Development and Evaluation (G
Cissus quadrangularis L. (Cissus) is a medicinal plant commonly used for centuries for various conditions, but lacks cr
A Review of Natural Stimulant and Non-stimulant Thermogenic Agents.
Stohs SJ, Badmaev V. Stohs SJ, et al. Phytother Res. 2016 May;30(5):732-40. doi: 10.1002/ptr.5583. Epub 2016 Feb 9. Phytother Res. 2016. PMID: 26856274 Free PMC article. Review.
Obesity and overweight are major health issues. Exercise and calorie intake control are recognized as the primary mechanisms for addressing excess body weight. ...The use of the aforementioned thermogenic agents in combination with other extracts such as those derived from
Obesity and overweight are major health issues. Exercise and calorie intake control are recognized as the primary mechanisms for addr
A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity.
Hasani-Ranjbar S, Nayebi N, Larijani B, Abdollahi M. Hasani-Ranjbar S, et al. World J Gastroenterol. 2009 Jul 7;15(25):3073-85. doi: 10.3748/wjg.15.3073. World J Gastroenterol. 2009. PMID: 19575486 Free PMC article. Review.
The search terms were "obesity" and ("herbal medicine" or "plant", "plant medicinal" or "medicine traditional") without narrowing or limiting search elements. ...Of the publications identified in the initial database, 915 results were identified and reviewed, and a total o …
The search terms were "obesity" and ("herbal medicine" or "plant", "plant medicinal" or "medicine traditional") without narrowing or …
Effectiveness of herbal medicines for weight loss: A systematic review and meta-analysis of randomized controlled trials.
Maunder A, Bessell E, Lauche R, Adams J, Sainsbury A, Fuller NR. Maunder A, et al. Diabetes Obes Metab. 2020 Jun;22(6):891-903. doi: 10.1111/dom.13973. Epub 2020 Feb 15. Diabetes Obes Metab. 2020. PMID: 31984610 Review.
A total of 54 randomized placebo-controlled trials of healthy overweight or obese adults were identified. Meta-analyses were conducted for herbal medicines with 4 studies available. ...Of the herbal medicines trialled in 3 randomized controlled trials, statistically and cl …
A total of 54 randomized placebo-controlled trials of healthy overweight or obese adults were identified. Meta-analyses were conducte …
Cissus quadrangularis extract (CQR-300) inhibits lipid accumulation by downregulating adipogenesis and lipogenesis in 3T3-L1 cells.
Lee HJ, Le B, Lee DR, Choi BK, Yang SH. Lee HJ, et al. Toxicol Rep. 2018 Mar 30;5:608-614. doi: 10.1016/j.toxrep.2018.02.008. eCollection 2018. Toxicol Rep. 2018. PMID: 29854631 Free PMC article.
The objective of this study was to evaluate the anti-obesity activity and the action mechanism of Cissus quadrangularis extracts (CQR-300) in 3T3-L1 adipocytes. Cissus quadrangularis was extracted with hot water, resulting in CQR-300. ...
The objective of this study was to evaluate the anti-obesity activity and the action mechanism of Cissus quadrangularis
The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress.
Oben JE, Enyegue DM, Fomekong GI, Soukontoua YB, Agbor GA. Oben JE, et al. Lipids Health Dis. 2007 Feb 4;6:4. doi: 10.1186/1476-511X-6-4. Lipids Health Dis. 2007. PMID: 17274828 Free PMC article. Clinical Trial.
The aim of this study was to compare the effect of a proprietary extract of Cissus quadrangularis (CQR-300) to that of a proprietary formulation containing CQR-300 (CORE) on weight, blood lipids, and oxidative stress in overweight and obese people. ...The inc …
The aim of this study was to compare the effect of a proprietary extract of Cissus quadrangularis (CQR-300) to that of a propr …
Evaluation of Natural Product Compositions for Appetite Suppression.
Yimam M, Jiao P, Hong M, Brownell L, Lee YC, Hyun EJ, Kim HJ, Kim TW, Nam JB, Kim MR, Jia Q. Yimam M, et al. J Diet Suppl. 2019;16(1):86-104. doi: 10.1080/19390211.2018.1429518. Epub 2018 Feb 14. J Diet Suppl. 2019. PMID: 29443598
In this in vivo acute feed intake study in rats, the appetite suppression efficacy of well-known natural ingredients in the weight-loss market were evaluated. We tested pure caffeine, potato skin extract, Cissus quadrangularis extract, Garcinia cambogia extract, Cro …
In this in vivo acute feed intake study in rats, the appetite suppression efficacy of well-known natural ingredients in the weight-loss mark …
Cissus Quadrangularis enhances UCP1 mRNA, indicative of white adipocyte browning and decreases central obesity in humans in a randomized trial.
Chatree S, Sitticharoon C, Maikaew P, Pongwattanapakin K, Keadkraichaiwat I, Churintaraphan M, Sripong C, Sririwichitchai R, Tapechum S. Chatree S, et al. Sci Rep. 2021 Jan 21;11(1):2008. doi: 10.1038/s41598-021-81606-9. Sci Rep. 2021. PMID: 33479386 Free PMC article.
Obesity is associated with the growth and expansion of adipocytes which could be decreased via several mechanisms. Cissus Quadrangularis (CQ) extract has been shown to reduce obesity in humans; however, its effect on human white adipocytes (hWA) has no
Obesity is associated with the growth and expansion of adipocytes which could be decreased via several mechanisms. Cissus Q
The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study.
Oben JE, Ngondi JL, Momo CN, Agbor GA, Sobgui CS. Oben JE, et al. Lipids Health Dis. 2008 Mar 31;7:12. doi: 10.1186/1476-511X-7-12. Lipids Health Dis. 2008. PMID: 18377661 Free PMC article. Clinical Trial.
AIM: To evaluate the effects of two formulations, Cissus quadrangularis-only and a Cissus quadrangularis/Irvingia gabonensis combination, on weight loss in overweight and obese human subjects. ...The participants were randomly divided into three …
AIM: To evaluate the effects of two formulations, Cissus quadrangularis-only and a Cissus quadrangularis/Irvingi …
Bioactivity-Guided Isolation and Identification of Anti-adipogenic Constituents from the n-Butanol Fraction of Cissus quadrangularis.
Toor RH, Khan ZN, Tariq M, Tassaduq R, Gardner QA, Waheed-Uz-Zaman W, Lian JB, Stein JL, Stein GS, Shakoori AR. Toor RH, et al. Crit Rev Eukaryot Gene Expr. 2020;30(6):519-541. doi: 10.1615/CritRevEukaryotGeneExpr.2020036843. Crit Rev Eukaryot Gene Expr. 2020. PMID: 33463919
Treatment options for obesity are limited, and available medications have many side effects. Thus there is a great need to find alternative medicines for treating obesity. This study explores the anti-adipogenic potential of the n-butanol fraction of Cissus
Treatment options for obesity are limited, and available medications have many side effects. Thus there is a great need to find alter …
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