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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
1999 1
2000 2
2001 3
2002 2
2003 2
2004 2
2005 2
2006 5
2007 4
2008 8
2009 3
2010 5
2011 8
2012 12
2013 25
2014 18
2015 14
2016 19
2017 19
2018 8
2019 7
2020 9
2021 8
2022 17
2023 12
2024 10
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2026 8

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224 results

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Page 1
A comparison of the risk of QT prolongation among SSRIs.
Funk KA, Bostwick JR. Funk KA, et al. Ann Pharmacother. 2013 Oct;47(10):1330-41. doi: 10.1177/1060028013501994. Epub 2013 Oct 21. Ann Pharmacother. 2013. PMID: 24259697 Review.
OBJECTIVE: To report QT prolongation potential in selective serotonin reuptake inhibitors (SSRIs) in order to advise clinicians on safe use of SSRIs other than citalopram in light of citalopram warnings. ...When citalopram is not utilized based on risk …
OBJECTIVE: To report QT prolongation potential in selective serotonin reuptake inhibitors (SSRIs) in order to advise clinicians on sa …
QT Prolongation, Torsades de Pointes, and Psychotropic Medications: A 5-Year Update.
Beach SR, Celano CM, Sugrue AM, Adams C, Ackerman MJ, Noseworthy PA, Huffman JC. Beach SR, et al. Psychosomatics. 2018 Mar-Apr;59(2):105-122. doi: 10.1016/j.psym.2017.10.009. Epub 2017 Nov 3. Psychosomatics. 2018. PMID: 29275963 Review.
BACKGROUND: Some psychotropic medications have been associated with prolongation of the QT interval and QT prolongation, especially in those with medical illness, and are linked to lethal ventricular arrhythmias, such as Torsades de Pointes (TdP). ...Escit …
BACKGROUND: Some psychotropic medications have been associated with prolongation of the QT interval and QT prolongation, espec …
Meta-analysis of selective serotonin reuptake inhibitor-associated QTc prolongation.
Beach SR, Kostis WJ, Celano CM, Januzzi JL, Ruskin JN, Noseworthy PA, Huffman JC. Beach SR, et al. J Clin Psychiatry. 2014 May;75(5):e441-9. doi: 10.4088/JCP.13r08672. J Clin Psychiatry. 2014. PMID: 24922496
Key words searched were QT, torsades de pointes, and sudden cardiac death, combined with antidepressants, citalopram, escitalopram, fluoxetine, sertraline, paroxetine, and fluvoxamine. ...With respect to specific SSRI agents, citalopram was asso …
Key words searched were QT, torsades de pointes, and sudden cardiac death, combined with antidepressants, citalopram, …
[Citalopram and QT prolongation].
Alušík Š, Paluch Z. Alušík Š, et al. Vnitr Lek. 2018 Winter;63(12):952-956. Vnitr Lek. 2018. PMID: 29334745 Review. Czech.
After analyzing the most relevant studies, the authors concluded that even papers published within the last 5 years confirmed that, of the SSRI class of drugs, citalopram prolongs the QT interval most significantly. While the QT interval prolongation in young …
After analyzing the most relevant studies, the authors concluded that even papers published within the last 5 years confirmed that, of the S …
Escitalopram in Adolescents With Generalized Anxiety Disorder: A Double-Blind, Randomized, Placebo-Controlled Study.
Strawn JR, Mills JA, Schroeder H, Mossman SA, Varney ST, Ramsey LB, Poweleit EA, Desta Z, Cecil K, DelBello MP. Strawn JR, et al. J Clin Psychiatry. 2020 Aug 25;81(5):20m13396. doi: 10.4088/JCP.20m13396. J Clin Psychiatry. 2020. PMID: 32857933 Free PMC article. Clinical Trial.
Vital signs, corrected QT interval, and adverse events were similar in patients who received escitalopram and placebo. ...Variation in CYP2C19 metabolism accounts for significant differences in escitalopram pharmacokinetics, raising the possibility that CYP2C …
Vital signs, corrected QT interval, and adverse events were similar in patients who received escitalopram and placebo. ...Vari …
Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial.
Porsteinsson AP, Drye LT, Pollock BG, Devanand DP, Frangakis C, Ismail Z, Marano C, Meinert CL, Mintzer JE, Munro CA, Pelton G, Rabins PV, Rosenberg PB, Schneider LS, Shade DM, Weintraub D, Yesavage J, Lyketsos CG; CitAD Research Group. Porsteinsson AP, et al. JAMA. 2014 Feb 19;311(7):682-91. doi: 10.1001/jama.2014.93. JAMA. 2014. PMID: 24549548 Free PMC article. Clinical Trial.
OBJECTIVE: The primary objective was to evaluate the efficacy of citalopram for agitation in patients with Alzheimer disease. Key secondary objectives examined effects of citalopram on function, caregiver distress, safety, cognitive safety, and tolerability. ...Wors …
OBJECTIVE: The primary objective was to evaluate the efficacy of citalopram for agitation in patients with Alzheimer disease. Key sec …
Abnormal Ca(2+) handling and reduced I(to) contribute to citalopram-induced QT prolongation and cardiac arrhythmias.
Li Y, Xie J, Zheng Y, Li J, Zhao M, Liu L, Shen H, Lei M, Tan X, Xiao J, Liu X, Chen T. Li Y, et al. Front Pharmacol. 2025 Sep 4;16:1613438. doi: 10.3389/fphar.2025.1613438. eCollection 2025. Front Pharmacol. 2025. PMID: 40978465 Free PMC article.
BACKGROUND: Citalopram (CIT) is widely used as an anti-depressant and has been reported to be associated with QT interval prolongation and increased vulnerability of torsades de pointes (TdP), although the underlying mechanism remains unclear. ...Finally, tra …
BACKGROUND: Citalopram (CIT) is widely used as an anti-depressant and has been reported to be associated with QT interval prol …
Detection of Clinically Significant Drug-Drug Interactions in Fatal Torsades de Pointes: Disproportionality Analysis of the Food and Drug Administration Adverse Event Reporting System.
Ji H, Gong M, Gong L, Zhang N, Zhou R, Deng D, Yang Y, Song L, Jia Y. Ji H, et al. J Med Internet Res. 2025 Mar 25;27:e65872. doi: 10.2196/65872. J Med Internet Res. 2025. PMID: 40132181 Free PMC article.
The most commonly interacting drugs were amiodarone, citalopram, quetiapine, ondansetron, ciprofloxacin, methadone, escitalopram, sotalol, and voriconazole. The most common combinations were citalopram and quetiapine, amiodarone and ciprofloxacin, amiodarone …
The most commonly interacting drugs were amiodarone, citalopram, quetiapine, ondansetron, ciprofloxacin, methadone, escitalopram …
Escitalopram Induced Angioedema.
Conde SL, Nazha H, Simpkins C. Conde SL, et al. Cureus. 2022 Nov 17;14(11):e31600. doi: 10.7759/cureus.31600. eCollection 2022 Nov. Cureus. 2022. PMID: 36540519 Free PMC article.
Due to QTc prolongation, her home medication of citalopram was discontinued in favor of escitalopram. Within 24 hours of administration, the patient experienced angioedema with periorbital swelling, lip swelling, and urticaria of the face and arms which was resolved …
Due to QTc prolongation, her home medication of citalopram was discontinued in favor of escitalopram. Within 24 hours of admin …
Citalopram and cardiac toxicity.
Cooke MJ, Waring WS. Cooke MJ, et al. Eur J Clin Pharmacol. 2013 Apr;69(4):755-60. doi: 10.1007/s00228-012-1408-1. Epub 2012 Sep 21. Eur J Clin Pharmacol. 2013. PMID: 22996077 Review.
RESULTS: The occurrence of electrocardiographic abnormalities has long been recognised as a complication of acute citalopram overdose; a dose-effect relationship for QT prolongation has been described in a number of large case series, including several cases of t …
RESULTS: The occurrence of electrocardiographic abnormalities has long been recognised as a complication of acute citalopram overdose …
224 results