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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 3
1991 11
1992 11
1993 19
1994 6
1995 29
1996 43
1997 46
1998 85
1999 92
2000 85
2001 86
2002 72
2003 88
2004 68
2005 63
2006 57
2007 63
2008 47
2009 38
2010 48
2011 54
2012 56
2013 64
2014 57
2015 61
2016 51
2017 48
2018 54
2019 50
2020 50
2021 49
2022 54
2023 36
2024 49
2025 44
2026 18

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1,744 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Clarithromycin as an adjunct to periodontal therapy: a systematic review and meta-analysis.
Bashir NZ, Sharma P. Bashir NZ, et al. Int J Dent Hyg. 2022 Feb;20(1):75-86. doi: 10.1111/idh.12498. Epub 2021 May 5. Int J Dent Hyg. 2022. PMID: 33773046
OBJECTIVE: To collate the literature evaluating the efficacy of clarithromycin as an adjunct to non-surgical periodontal therapy and conduct meta-analyses for changes in probing pocket depth (PPD) and clinical attachment level (CAL). ...CONCLUSIONS: The use of locally deli …
OBJECTIVE: To collate the literature evaluating the efficacy of clarithromycin as an adjunct to non-surgical periodontal therapy and …
Clarithromycin for the treatment of adult chronic rhinosinusitis: a systematic review and meta-analysis.
Huang Z, Zhou B. Huang Z, et al. Int Forum Allergy Rhinol. 2019 May;9(5):545-555. doi: 10.1002/alr.22281. Epub 2019 Jan 10. Int Forum Allergy Rhinol. 2019. PMID: 30629811
Eleven studies evaluated whether adding oral clarithromycin to intranasal steroid spray with or without nasal saline irrigation was more effective than intranasal steroid spray alone. ...No significant difference was identified between treatment with oral clarithromycin …
Eleven studies evaluated whether adding oral clarithromycin to intranasal steroid spray with or without nasal saline irrigation was m …
The clinical effectiveness of clarithromycin versus endoscopic sinus surgery for adults with chronic rhinosinusitis with and without nasal polyps (MACRO): a pragmatic, multicentre, three-arm, randomised, placebo-controlled phase 4 trial.
Philpott C, Beard DJ, Saeedi E, Cook JA, Jones S, Clarke CS, Teoh L, Thomas M, Little P, Vennik J, Lund V, Schilder AGM, Long F, Durham S, Boardman J, Hopkins C; MACRO Collaborative; MACRO Programme Team. Philpott C, et al. Lancet. 2025 Aug 30;406(10506):926-939. doi: 10.1016/S0140-6736(25)01248-6. Lancet. 2025. PMID: 40885584 Free article. Clinical Trial.
Adverse reactions were assessed in the safety population (clarithromycin and placebo), and serious adverse events in the ITT population (all groups). ...Conversely, the trial findings do not support routine long-term use of low-dose clarithromycin. Endoscopic sinus …
Adverse reactions were assessed in the safety population (clarithromycin and placebo), and serious adverse events in the ITT populati …
Heteroresistance to clarithromycin and metronidazole in patients with a Helicobacter pylori infection: a systematic review and meta-analysis.
Kouhsari E, Sadeghifard N, Khadiv A, Sayadi H, Amiriani T, Ghafourian S, Valadbeigi H, Krutova M. Kouhsari E, et al. Ann Clin Microbiol Antimicrob. 2022 May 20;21(1):19. doi: 10.1186/s12941-022-00509-3. Ann Clin Microbiol Antimicrob. 2022. PMID: 35596211 Free PMC article.
The study outcomes were the weighted pooled prevalence of heteroresistance to clarithromycin and metronidazole in H. pylori positive samples and/or isolates with a subanalysis by continent. ...CONCLUSION: The prevalence of heteroresistance to clarithromycin and/or m …
The study outcomes were the weighted pooled prevalence of heteroresistance to clarithromycin and metronidazole in H. pylori positive …
Clarithromycin for improved clinical outcomes in community-acquired pneumonia: A subgroup analysis of the ACCESS trial.
Akinosoglou K, Leventogiannis K, Tasouli E, Kakavoulis N, Niotis G, Doulou S, Skorda L, Iliopoulou K, Papailiou A, Katsaounou P, Rapti V, Chrysos G, Seferlis T, Gerakari S, Dakou K, Papanikolaou IC, Milionis H, Kewitz S, Georgiadou S, Kontopoulou T, Tzavara V, Torres A, Niederman MS, Giamarellos-Bourboulis EJ. Akinosoglou K, et al. Int J Antimicrob Agents. 2025 Feb;65(2):107406. doi: 10.1016/j.ijantimicag.2024.107406. Epub 2024 Dec 6. Int J Antimicrob Agents. 2025. PMID: 39647798 Free article. Clinical Trial.
RESULTS: The addition of clarithromycin significantly increased the proportion of patients achieving the primary endpoint across all subgroups and decreased the need for MV in 19 out of the 37 subgroups studied. ...The addition of corticosteroids alone was not as clinicall …
RESULTS: The addition of clarithromycin significantly increased the proportion of patients achieving the primary endpoint across all …
Global Estimate of Clarithromycin Resistance in Clinical Isolates of Helicobacter pylori: a Systematic Review and Meta-Analysis.
Khoshnood S, Pakzad R, Kaviar VH, Hashemian M, Karamollahi S, Sadeghifard N, Heidarizadeh H, Moradi M, Maleki A, Heidary M, Abdi M. Khoshnood S, et al. Clin Lab. 2023 Jul 1;69(7). doi: 10.7754/Clin.Lab.2022.221032. Clin Lab. 2023. PMID: 37436391
BACKGROUND: A high resistance rate to clarithromycin usually leads to failure to eradicate Helicobacter pylori. The aim of the present study was to review recent data on H. pylori resistance towards clarithromycin in clinical studies worldwide. ...CONCLUSIONS: H. py …
BACKGROUND: A high resistance rate to clarithromycin usually leads to failure to eradicate Helicobacter pylori. The aim of the presen …
Clarithromycin. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic potential.
Peters DH, Clissold SP. Peters DH, et al. Drugs. 1992 Jul;44(1):117-64. doi: 10.2165/00003495-199244010-00009. Drugs. 1992. PMID: 1379907 Review.
Clarithromycin is an acid-stable orally administered macrolide antimicrobial drug, structurally related to erythromycin. ...However, bacterial strains resistant to erythromycin are also generally resistant to clarithromycin. The antimicrobial activity of clarithr …
Clarithromycin is an acid-stable orally administered macrolide antimicrobial drug, structurally related to erythromycin. ...However, …
Characterization of clarithromycin-resistant Helicobacter pylori strains in Iran: A systematic review and meta-analysis.
Khademi F, Sahebkar AH, Vaez H, Arzanlou M, Peeridogaheh H. Khademi F, et al. J Glob Antimicrob Resist. 2017 Sep;10:171-178. doi: 10.1016/j.jgar.2017.05.021. Epub 2017 Jul 18. J Glob Antimicrob Resist. 2017. PMID: 28732793
Point mutations in the 23S rRNA gene are one of the main mechanisms leading to the resistance to clarithromycin in Iran. The purpose of the present review was to evaluate the prevalence of clarithromycin-resistant H. pylori strains in Iran and to identify the major …
Point mutations in the 23S rRNA gene are one of the main mechanisms leading to the resistance to clarithromycin in Iran. The purpose …
Clinical And Bacteriological Impact Of Clarithromycin In Streptococcal Pharyngitis: Findings From A Meta-Analysis Of Clinical Trials.
Hoban DJ, Nauta J. Hoban DJ, et al. Drug Des Devel Ther. 2019 Oct 16;13:3551-3558. doi: 10.2147/DDDT.S205820. eCollection 2019. Drug Des Devel Ther. 2019. PMID: 31802844 Free PMC article.
A 2012 meta-review and a 2016 Cochrane systematic review reported favorably on the comparative efficacy and safety of clarithromycin in pediatric patients with URTIs and in adults with GABHS pharyngitis. In this paper, the evidence base for clarithromycin in patient …
A 2012 meta-review and a 2016 Cochrane systematic review reported favorably on the comparative efficacy and safety of clarithromycin …
Efficacy of erythromycin compared to clarithromycin and azithromycin in adults or adolescents with community-acquired pneumonia: A Systematic Review and meta-analysis of randomized controlled trials.
Ashy N, Alharbi L, Alkhamisi R, Alradadi R, Eljaaly K. Ashy N, et al. J Infect Chemother. 2022 Aug;28(8):1148-1152. doi: 10.1016/j.jiac.2022.04.020. Epub 2022 May 3. J Infect Chemother. 2022. PMID: 35523718
The aim of this meta-analysis is to compare the efficacy of erythromycin with clarithromycin and azithromycin. METHODS: We performed this meta-analysis of randomized controlled trials (RCTs) of adults or adolescents with CAP which compared the efficacy of erythromycin mono …
The aim of this meta-analysis is to compare the efficacy of erythromycin with clarithromycin and azithromycin. METHODS: We performed …
1,744 results