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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
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1978 3
1979 1
1980 3
1981 2
1982 3
1983 2
1984 2
1985 4
1986 1
1987 3
1988 2
1989 4
1990 5
1991 2
1992 2
1993 2
1994 5
1995 5
1996 2
1997 2
1999 2
2000 1
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2015 1
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2018 2
2019 1
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2024 0

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74 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial.
Green AJ, Gelfand JM, Cree BA, Bevan C, Boscardin WJ, Mei F, Inman J, Arnow S, Devereux M, Abounasr A, Nobuta H, Zhu A, Friessen M, Gerona R, von Büdingen HC, Henry RG, Hauser SL, Chan JR. Green AJ, et al. Lancet. 2017 Dec 2;390(10111):2481-2489. doi: 10.1016/S0140-6736(17)32346-2. Epub 2017 Oct 10. Lancet. 2017. PMID: 29029896 Clinical Trial.
Patients were randomly assigned (1:1) via block randomisation using a random number generator to receive either clemastine fumarate (5.36 mg orally twice daily) for 90 days followed by placebo for 60 days (group 1), or placebo for 90 days followed by clemastine fuma …
Patients were randomly assigned (1:1) via block randomisation using a random number generator to receive either clemastine fumarate ( …
Effect of Clemastine Fumarate on Perioperative Hemodynamic Instability Mediated by Anaphylaxis During Cardiopulmonary Bypass Surgery.
Tian L, Liu Y, Fei Y, Lv H, Yan F, Li L, Shi J. Tian L, et al. Med Sci Monit. 2022 Jun 2;28:e936367. doi: 10.12659/MSM.936367. Med Sci Monit. 2022. PMID: 35651299 Free PMC article. Clinical Trial.
This study aimed to evaluate the effect of clemastine fumarate in this specific patient population. MATERIAL AND METHODS We enrolled 100 participants who met the inclusion criteria and randomly allocated them to the treatment group and the placebo group. Participants in th …
This study aimed to evaluate the effect of clemastine fumarate in this specific patient population. MATERIAL AND METHODS We enrolled …
Effect of the H(1)-antihistamine clemastine on PACAP38 induced migraine.
Vollesen LH, Guo S, Andersen MR, Ashina M. Vollesen LH, et al. Cephalalgia. 2019 Apr;39(5):597-607. doi: 10.1177/0333102418798611. Epub 2018 Aug 30. Cephalalgia. 2019. PMID: 30165750 Clinical Trial.
OBJECTIVE: To investigate the effect of the H(1)-antihistamine clemastine on the migraine-inducing abilities of pituitary adenylate cyclase activating peptide-38. ...Twenty migraine without aura patients were randomly allocated to receive bolus clemastine 2 mg (1 mg …
OBJECTIVE: To investigate the effect of the H(1)-antihistamine clemastine on the migraine-inducing abilities of pituitary adenylate c …
Clemastine causes immune suppression through inhibition of extracellular signal-regulated kinase-dependent proinflammatory cytokines.
Johansen P, Weiss A, Bünter A, Waeckerle-Men Y, Fettelschoss A, Odermatt B, Kündig TM. Johansen P, et al. J Allergy Clin Immunol. 2011 Dec;128(6):1286-94. doi: 10.1016/j.jaci.2011.06.023. Epub 2011 Jul 31. J Allergy Clin Immunol. 2011. PMID: 21807405 Clinical Trial.
Finally, therapeutic application of clemastine-mediated immune suppression was tested in a murine model of sepsis. RESULTS: Clemastine and desloratadine strongly reduced innate responses to Listeria monocytogenes in mice as did dexamethasone. ...Moreover, in a doubl …
Finally, therapeutic application of clemastine-mediated immune suppression was tested in a murine model of sepsis. RESULTS: Clemas …
The pharmacokinetics and bioavailability of clemastine and phenylpropanolamine in single-component and combination formulations.
Schran HF, Petryk L, Chang CT, O'Connor R, Gelbert MB. Schran HF, et al. J Clin Pharmacol. 1996 Oct;36(10):911-22. doi: 10.1002/j.1552-4604.1996.tb04758.x. J Clin Pharmacol. 1996. PMID: 8930778 Clinical Trial.
Clemastine solution and tablets were bioequivalent, and food had no significant effect on rate and extent of absorption of clemastine. The 1- and 2-mg clemastine tablets showed proportional bioavailability. Coadministration of clemastine with phenylpro …
Clemastine solution and tablets were bioequivalent, and food had no significant effect on rate and extent of absorption of clemast …
Low dose clemastine inhibits sneezing and rhinorrhea during the early nasal allergic reaction.
Chung JH, deTineo ML, Naclerio RM, Sorrentino JV, Winslow CM, Baroody FM. Chung JH, et al. Ann Allergy Asthma Immunol. 1997 Mar;78(3):307-12. doi: 10.1016/S1081-1206(10)63187-0. Ann Allergy Asthma Immunol. 1997. PMID: 9087158 Clinical Trial.
BACKGROUND: Clemastine (1 mg) is currently available over-the-counter for the treatment of allergic rhinitis. ...Clemastine administered four and six hours before challenge reduced sneezing significantly more than clemastine administered one hour before chall …
BACKGROUND: Clemastine (1 mg) is currently available over-the-counter for the treatment of allergic rhinitis. ...Clemastine ad …
Administration of clemastine--H1 histamine receptor blocker in the prevention of haemodynamic disorders after protamine sulfate administration in patients subjected to coronary artery bypass grafting in extracorporeal circulation.
Lango R, Mroziński P, Wujtewicz M, Suchorzewska J, Rogowski J, Narkiewicz M, Siebert J. Lango R, et al. Med Sci Monit. 2000 Jul-Aug;6(4):769-75. Med Sci Monit. 2000. PMID: 11208407 Free article. Clinical Trial.
Control group (n = 27) did not receive clemastine, Clemastine group (n = 26) received 2 mg i.v. clemastine, before CPB. After CPB were completed, patients were given protamine (heparin to protamine ratio--1:1.5) within 7 minutes, through peripheral vein. ...I …
Control group (n = 27) did not receive clemastine, Clemastine group (n = 26) received 2 mg i.v. clemastine, before CPB. …
Effectiveness of clemastine fumarate for treatment of rhinorrhea and sneezing associated with the common cold.
Turner RB, Sperber SJ, Sorrentino JV, O'Connor RR, Rogers J, Batouli AR, Gwaltney JM Jr. Turner RB, et al. Clin Infect Dis. 1997 Oct;25(4):824-30. doi: 10.1086/515546. Clin Infect Dis. 1997. PMID: 9356796 Clinical Trial.
At baseline (day 1), the mean symptom-severity scores +/- SEM for the clemastine fumarate and placebo groups were not significantly different. The mean rhinorrhea-severity score +/- SEM was not different on day 2; however, on day 3, the mean rhinorrhea-severity score +/- S …
At baseline (day 1), the mean symptom-severity scores +/- SEM for the clemastine fumarate and placebo groups were not significantly d …
A comparison between the efficacy of ketotifen and clemastine in children.
Hlousková Z, Gutová M, Hlousek Z. Hlousková Z, et al. J Int Med Res. 1980;8(6):408-12. doi: 10.1177/030006058000800608. J Int Med Res. 1980. PMID: 6108265 Clinical Trial.
In a controlled single-blind study of 12 weeks' duration the prophylactic anti-asthmatic effects of ketotifen and clemastine in children with bronchial asthma were compared. The drugs were administered in syrup form in doses from 1 to 2 mg per day according to the body-wei …
In a controlled single-blind study of 12 weeks' duration the prophylactic anti-asthmatic effects of ketotifen and clemastine in child …
Effects of clemastine, ketotifen and prednisolone on chloroquine-induced pruritus.
Abila B, Ikueze R. Abila B, et al. J Trop Med Hyg. 1989 Oct;92(5):356-9. J Trop Med Hyg. 1989. PMID: 2810454 Clinical Trial.
The effects of single doses of placebo, clemastine, ketotifen and prednisolone on chloroquine-induced pruritus were investigated in healthy black African volunteers using a visual analogue scale. There was no significant differences between the mean percentage degrees of p …
The effects of single doses of placebo, clemastine, ketotifen and prednisolone on chloroquine-induced pruritus were investigated in h …
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