Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1965 4
1966 5
1968 2
1969 2
1970 3
1973 3
1974 2
1975 1
1976 4
1977 5
1978 5
1979 2
1980 3
1981 3
1982 8
1983 19
1984 16
1985 11
1986 24
1987 24
1988 44
1989 47
1990 73
1991 71
1992 61
1993 90
1994 139
1995 152
1996 156
1997 173
1998 191
1999 214
2000 227
2001 202
2002 222
2003 262
2004 295
2005 317
2006 336
2007 350
2008 409
2009 441
2010 555
2011 550
2012 627
2013 825
2014 1024
2015 1163
2016 1185
2017 1401
2018 1516
2019 1572
2020 1791
2021 2010
2022 1849
2023 1820
2024 2068
2025 1365

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

23,179 results

Results by year

Filters applied: . Clear all
Page 1
Bayesian Clinical Trials.
Clark J, Muhlemann N, Ionan A. Clark J, et al. Ther Innov Regul Sci. 2023 May;57(3):399-400. doi: 10.1007/s43441-023-00498-1. Epub 2023 Jan 31. Ther Innov Regul Sci. 2023. PMID: 36719596
The following is an introduction from the guest editors for the Bayesian Clinical Trials series....
The following is an introduction from the guest editors for the Bayesian Clinical Trials series....
Artificial Intelligence in Cardiovascular Clinical Trials.
Cunningham JW, Abraham WT, Bhatt AS, Dunn J, Felker GM, Jain SS, Lindsell CJ, Mace M, Martyn T, Shah RU, Tison GH, Fakhouri T, Psotka MA, Krumholz H, Fiuzat M, O'Connor CM, Solomon SD; Heart Failure Collaboratory. Cunningham JW, et al. J Am Coll Cardiol. 2024 Nov 12;84(20):2051-2062. doi: 10.1016/j.jacc.2024.08.069. J Am Coll Cardiol. 2024. PMID: 39505413 Free PMC article. Review.
Randomized clinical trials are the gold standard for establishing the efficacy and safety of cardiovascular therapies. ...
Randomized clinical trials are the gold standard for establishing the efficacy and safety of cardiovascular therapies. ...
Huntington's Disease Clinical Trials Corner: March 2024.
Estevez-Fraga C, Tabrizi SJ, Wild EJ. Estevez-Fraga C, et al. J Huntingtons Dis. 2024;13(1):1-14. doi: 10.3233/JHD-240017. J Huntingtons Dis. 2024. PMID: 38489195 Free PMC article.
In this edition of the Huntington's Disease Clinical Trials Update, we expand on the ongoing program from VICO Therapeutics and on the recently terminated VIBRANT-HD clinical trials. We also discuss updates from uniQure's AMT-130 program and PTC therap …
In this edition of the Huntington's Disease Clinical Trials Update, we expand on the ongoing program from VICO Therapeutics an …
Clinical trials.
Minneci PC, Deans KJ. Minneci PC, et al. Semin Pediatr Surg. 2018 Dec;27(6):332-337. doi: 10.1053/j.sempedsurg.2018.10.003. Epub 2018 Oct 24. Semin Pediatr Surg. 2018. PMID: 30473036 Review.
Clinical trials can be used to generate data on safety, efficacy, and/or effectiveness of treatments. ...Critical issues to consider when either designing a trial or interpreting the results of a trial include evaluating the validity and generalizability of the resu …
Clinical trials can be used to generate data on safety, efficacy, and/or effectiveness of treatments. ...Critical issues to co …
Key cost drivers of pharmaceutical clinical trials in the United States.
Sertkaya A, Wong HH, Jessup A, Beleche T. Sertkaya A, et al. Clin Trials. 2016 Apr;13(2):117-26. doi: 10.1177/1740774515625964. Epub 2016 Feb 8. Clin Trials. 2016. PMID: 26908540
BACKGROUND: The increasing cost of clinical research has significant implications for public health, as it affects drug companies' willingness to undertake clinical trials, which in turn limits patient access to novel treatments. Thus, gaining a better understanding …
BACKGROUND: The increasing cost of clinical research has significant implications for public health, as it affects drug companies' willingne …
Clinical trials at AHCs: the perspective of an academic clinical trials office.
Paller MS, Hostetler L, Dykhuis DA. Paller MS, et al. Acad Med. 2002 Dec;77(12 Pt 1):1201-6. doi: 10.1097/00001888-200212000-00008. Acad Med. 2002. PMID: 12480622 Review.
In academia's efforts to reclaim lost ground with respect to the performance of industry-sponsored clinical trials, many academic health centers have established clinical trials offices. ...Reasons for not participating in specific clinical …
In academia's efforts to reclaim lost ground with respect to the performance of industry-sponsored clinical trials, many acade …
Real-World Evidence - What Is It and What Can It Tell Us?
Sherman RE, Anderson SA, Dal Pan GJ, Gray GW, Gross T, Hunter NL, LaVange L, Marinac-Dabic D, Marks PW, Robb MA, Shuren J, Temple R, Woodcock J, Yue LQ, Califf RM. Sherman RE, et al. N Engl J Med. 2016 Dec 8;375(23):2293-2297. doi: 10.1056/NEJMsb1609216. N Engl J Med. 2016. PMID: 27959688 No abstract available.
The conundrum of office-based clinical trials.
Scott LD. Scott LD. Am J Gastroenterol. 2007 Feb;102(2):232-5. doi: 10.1111/j.1572-0241.2006.01027.x. Am J Gastroenterol. 2007. PMID: 17311645 Review. No abstract available.
Efficient design of clinical trials and epidemiological research: is it possible?
Lauer MS, Gordon D, Wei G, Pearson G. Lauer MS, et al. Nat Rev Cardiol. 2017 Aug;14(8):493-501. doi: 10.1038/nrcardio.2017.60. Epub 2017 Apr 27. Nat Rev Cardiol. 2017. PMID: 28447664 Review.
Randomized clinical trials and large-scale, cohort studies continue to have a critical role in generating evidence in cardiovascular medicine; however, the increasing concern is that ballooning costs threaten the clinical trial enterprise. In this Perspectives artic …
Randomized clinical trials and large-scale, cohort studies continue to have a critical role in generating evidence in cardiova …
Pragmatic Clinical Trials in Neurology.
Qureshi AI, Bartlett-Esquilant G, Brown A, McClay J, Pasnoor M, Barohn RJ. Qureshi AI, et al. Ann Neurol. 2025 Jun;97(6):1022-1037. doi: 10.1002/ana.27244. Epub 2025 Apr 22. Ann Neurol. 2025. PMID: 40260697 Review.
The need for pragmatic clinical trials evaluating therapeutic interventions in patients with neurological disease is continually increasing due to availability of multiple therapeutic interventions (comparative effectiveness), multifaceted approaches (multiple concu …
The need for pragmatic clinical trials evaluating therapeutic interventions in patients with neurological disease is continual …
23,179 results
You have reached the last available page of results. Please see the User Guide for more information.