Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 2
1985 1
1995 1
1998 1
1999 1
2000 1
2002 1
2010 1
2011 5
2012 5
2013 3
2015 8
2016 6
2017 11
2018 15
2019 24
2020 27
2021 34
2022 53
2023 62
2024 55
2025 11

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

302 results

Results by year

Filters applied: . Clear all
Page 1
A rapid genome-proteome approach to identify rate-limiting steps in the butyrate production pathway in probiotic Clostridium butyricum, CBM588.
Wood L, Omorotionmwan BB, Blanchard AM, Dowle A, Tooth D, Bailey TS, Griffin R. Wood L, et al. Anaerobe. 2025 Jan 30:102940. doi: 10.1016/j.anaerobe.2025.102940. Online ahead of print. Anaerobe. 2025. PMID: 39892707 Free article.
OBJECTIVES: Clostridium butyricum ferments non-digested dietary fibre in the colon to produce butyric acid. ...CONCLUSIONS: Our findings pave the way for over-expressing these genes chromosomally to generate a recombinant probiotic with improved butyrate production …
OBJECTIVES: Clostridium butyricum ferments non-digested dietary fibre in the colon to produce butyric acid. ...CONCLUSIONS: Ou …
Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.
Wang T, Chen J, Shu C, Shen X, Fu Y, Li M, Luo Z. Wang T, et al. Acta Biomater. 2025 Jan 28:S1742-7061(25)00069-8. doi: 10.1016/j.actbio.2025.01.049. Online ahead of print. Acta Biomater. 2025. PMID: 39884521
Herein, we report a multifunctional supramolecular probiotic capsule based on clinically-tested biopolymers for UC therapy, which not only allow colon-targeted probiotic delivery via oral route but also enable concurrent delivery of hemostatic and anti-inflammatory drugs. Specifi …
Herein, we report a multifunctional supramolecular probiotic capsule based on clinically-tested biopolymers for UC therapy, which not only a …
Microbiota in patients with cefuroxime resistance and anal fistula revealed by 16S ribosomal DNA.
Ling YT, Yao F, Li SJ, Cao CX, Chen ZW, Qiu M, Li BZ, Hu BW, Zhong SY, Hu GL, Li JH. Ling YT, et al. World J Gastrointest Surg. 2025 Jan 27;17(1):100790. doi: 10.4240/wjgs.v17.i1.100790. World J Gastrointest Surg. 2025. PMID: 39872785 Free PMC article.
Patients in the Cefur-NS group received a 7-day course of Clostridium butyricum tablets. Post-intervention, microbial composition and cefuroxime resistance were reassessed. ...Probiotic intervention targeting gut microbiota composition presents a promising st …
Patients in the Cefur-NS group received a 7-day course of Clostridium butyricum tablets. Post-intervention, microbial composit …
The combination of Clostridium butyricum and Akkermansia muciniphila mitigates DSS-induced colitis and attenuates colitis-associated tumorigenesis by modulating gut microbiota and reducing CD8(+) T cells in mice.
Hua D, Yang Q, Li X, Zhou X, Kang Y, Zhao Y, Wu D, Zhang Z, Li B, Wang X, Qi X, Chen Z, Cui G, Hong W. Hua D, et al. mSystems. 2025 Jan 22:e0156724. doi: 10.1128/msystems.01567-24. Online ahead of print. mSystems. 2025. PMID: 39840995 Free article.
The gut microbiota is closely associated with inflammatory bowel disease (IBD) and colorectal cancer (CRC). Probiotics such as Clostridium butyricum (CB) or Akkermansia muciniphila (AKK) have the potential to treat inflammatory bowel disease (IBD) or colorect …
The gut microbiota is closely associated with inflammatory bowel disease (IBD) and colorectal cancer (CRC). Probiotics such as Clo
Isolation and Evaluation of Potential Use of Prebiotics-Utilizing Butyrate-Producing Bacteria in Nibea coibor.
Li Z, Tran NT, Zhang M, Li Z, Yang W, Wang S, Hu Z, Li S. Li Z, et al. Aquac Nutr. 2025 Jan 11;2025:4679037. doi: 10.1155/anu/4679037. eCollection 2025. Aquac Nutr. 2025. PMID: 39830087 Free PMC article.
The results showed that nine isolates were obtained in vitro from the gut of N. coibor, including six Clostridium butyricum, two Proteocatella sphenisci, and one Fusobacterium varium. ...Our results suggested the potential use of C. butyricum CG-1 or P …
The results showed that nine isolates were obtained in vitro from the gut of N. coibor, including six Clostridium butyricum
Clinical Applications of Microbiome in Renal Cell Carcinoma.
Elyas S, Barata P, Vaishampayan U. Elyas S, et al. Eur Urol Focus. 2025 Jan 16:S2405-4569(24)00264-5. doi: 10.1016/j.euf.2024.12.006. Online ahead of print. Eur Urol Focus. 2025. PMID: 39824679 Review.
While immune checkpoint inhibitors (ICIs) have improved survival in metastatic RCC, composition of the gut microbiome has the potential to influence their efficacy. Antibiotic-induced microbiome disruptions correlate with diminished outcomes, while strains such as Akkerman …
While immune checkpoint inhibitors (ICIs) have improved survival in metastatic RCC, composition of the gut microbiome has the potenti …
Analysis of long Non-Coding RNA and mRNA expression in Clostridium butyricum-Induced apoptosis in SW480 colon cancer cells.
Yang X, Wei L. Yang X, et al. Gene. 2025 Mar 10;940:149208. doi: 10.1016/j.gene.2024.149208. Epub 2025 Jan 2. Gene. 2025. PMID: 39755264
Colon cancer is a leading cause of cancer-related deaths worldwide and has been increasingly linked to the gut microbiome. Clostridium butyricum (CB), a probiotic, has demonstrated potential in influencing colon cancer cell behavior, particularly through the …
Colon cancer is a leading cause of cancer-related deaths worldwide and has been increasingly linked to the gut microbiome. Clostri
Hypoglycemic effect of C. butyricum-pMTL007-GLP-1 engineered probiotics on type 2 diabetes mellitus.
Zhou D, Li S, Hu G, Wang Y, Qi Z, Xu X, Wei J, Liu Q, Chen T. Zhou D, et al. Gut Microbes. 2025 Dec;17(1):2447814. doi: 10.1080/19490976.2024.2447814. Epub 2025 Jan 2. Gut Microbes. 2025. PMID: 39745177 Free article.
However, its limitation lies in its short plasma half-life, necessitating the continuous intravenous injection of GLP-1 drugs to achieve efficacy. Here, we engineered Clostridium butyricum to continuously express and deliver GLP-1 (denoted as Cb-GLP-1), and assessed …
However, its limitation lies in its short plasma half-life, necessitating the continuous intravenous injection of GLP-1 drugs to achieve eff …
The effect of Miya on skeletal muscle changes by regulating gut microbiota in rats with osteoarthritis through AMPK pathway.
Wang S, Duan Z, Li Z, Yang D, Lu H, Zhang Y, Fu Y, Guan Y, Li G, Qian F, Xu T. Wang S, et al. BMC Musculoskelet Disord. 2024 Dec 30;25(1):1081. doi: 10.1186/s12891-024-08203-5. BMC Musculoskelet Disord. 2024. PMID: 39736635 Free PMC article.
BACKGROUND: The study aimed to explore whether Miya (MY), a kind of Clostridium butyricum, regulated osteoarthritis (OA) progression through adenosine 5'-monophosphate-activated protein kinase (AMPK) pathway. ...
BACKGROUND: The study aimed to explore whether Miya (MY), a kind of Clostridium butyricum, regulated osteoarthritis (OA) progr …
Clostridium butyricum, a future star in sepsis treatment.
Zhao J, Jiang L, He W, Han D, Yang X, Wu L, Zhong H. Zhao J, et al. Front Cell Infect Microbiol. 2024 Dec 6;14:1484371. doi: 10.3389/fcimb.2024.1484371. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 39711782 Free PMC article. Review.
Recent evidence suggests that intestinal flora dysbiosis plays a crucial role in sepsis. Clostridium butyricum (C. butyricum), which has been used as a probiotic in poultry feed since its discovery, has been found to play a potential protective role in intest …
Recent evidence suggests that intestinal flora dysbiosis plays a crucial role in sepsis. Clostridium butyricum (C. butyricu
302 results