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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
2002 1
2006 1
2008 1
2010 1
2012 2
2013 2
2014 3
2015 1
2017 3
2018 5
2019 1
2020 4
2021 1
2022 6
2023 3
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43 results

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Page 1
Cobalt toxicity in humans-A review of the potential sources and systemic health effects.
Leyssens L, Vinck B, Van Der Straeten C, Wuyts F, Maes L. Leyssens L, et al. Toxicology. 2017 Jul 15;387:43-56. doi: 10.1016/j.tox.2017.05.015. Epub 2017 May 29. Toxicology. 2017. PMID: 28572025 Free article. Review.
Although cobalt has a biologically necessary role as metal constituent of vitamin B(12), excessive exposure has been shown to induce various adverse health effects. ...Oral intake of Co supplements and internal exposure through metal-on-metal (MoM) hip implan …
Although cobalt has a biologically necessary role as metal constituent of vitamin B(12), excessive exposure has been shown to induce …
A review of the health hazards posed by cobalt.
Paustenbach DJ, Tvermoes BE, Unice KM, Finley BL, Kerger BD. Paustenbach DJ, et al. Crit Rev Toxicol. 2013 Apr;43(4):316-62. doi: 10.3109/10408444.2013.779633. Crit Rev Toxicol. 2013. PMID: 23656559 Review.
Adverse health effects, such as cardiomyopathy and vision or hearing impairment, were reported at peak blood Co concentrations typically over 700 g/L (8-40 weeks), while reversible hypothyroidism and polycythemia were reported in humans at ~300 g/L and high …
Adverse health effects, such as cardiomyopathy and vision or hearing impairment, were reported at peak blood Co concentrations …
Effects of lithium nickel manganese cobalt oxide exposure on biological age acceleration: Insights from metabolomics.
Liu W, Deng Y, Li G, Yang L, Wu Y, Hu Y, Yang J, Xian S, Yi M, Yang Q, Bai Y, Liu L. Liu W, et al. Ecotoxicol Environ Saf. 2025 Sep 1;302:118733. doi: 10.1016/j.ecoenv.2025.118733. Epub 2025 Jul 23. Ecotoxicol Environ Saf. 2025. PMID: 40706517 Free article.
The Lithium nickel manganese cobalt oxide (NCM) is a representative new energy material widely used in industry and daily life, but the systemic health influence of exposure to NCM remained largely unknown. ...Li was the critical component to NCM exposure …
The Lithium nickel manganese cobalt oxide (NCM) is a representative new energy material widely used in industry and daily life, but t …
Interpreting cobalt blood concentrations in hip implant patients.
Paustenbach DJ, Galbraith DA, Finley BL. Paustenbach DJ, et al. Clin Toxicol (Phila). 2014 Feb;52(2):98-112. doi: 10.3109/15563650.2013.857024. Epub 2013 Nov 20. Clin Toxicol (Phila). 2014. PMID: 24256093 Review.
There has been some recent concern regarding possible systemic health effects resulting from elevated blood cobalt concentrations in patients with cobalt containing hip implants. To date there are no blood cobalt criteria to help guide ph …
There has been some recent concern regarding possible systemic health effects resulting from elevated blood cobalt
A systematic comparison of the actual, potential, and theoretical health effects of cobalt and chromium exposures from industry and surgical implants.
Keegan GM, Learmonth ID, Case CP. Keegan GM, et al. Crit Rev Toxicol. 2008;38(8):645-74. doi: 10.1080/10408440701845534. Crit Rev Toxicol. 2008. PMID: 18720105 Review.
Humans are exposed to cobalt (Co) and chromium (Cr) from industry and surgical devices, most notably orthopedic joint replacements. This review compares the potential health effects of exposure to Co and Cr contaminants from these two different sources
Humans are exposed to cobalt (Co) and chromium (Cr) from industry and surgical devices, most notably orthopedic joint replacem
Safety and activity of CTX130, a CD70-targeted allogeneic CRISPR-Cas9-engineered CAR T-cell therapy, in patients with relapsed or refractory T-cell malignancies (COBALT-LYM): a single-arm, open-label, phase 1, dose-escalation study.
Iyer SP, Sica RA, Ho PJ, Prica A, Zain J, Foss FM, Hu B, Beitinjaneh A, Weng WK, Kim YH, Khodadoust MS, Huen AO, Williams LM, Ma A, Huang E, Ganpule A, Nagar SD, Sripakdeevong P, Cullingford EL, Karnik S, Dequeant ML, Patel JN, He XS, Li Z, He QA, Mendonez JH, Keegan A, Horwitz SM. Iyer SP, et al. Lancet Oncol. 2025 Jan;26(1):110-122. doi: 10.1016/S1470-2045(24)00508-4. Epub 2024 Nov 29. Lancet Oncol. 2025. PMID: 39617017 Free PMC article. Clinical Trial.
The primary endpoint was the incidence of adverse events, defined as dose-limiting toxicities occurring within 28 days post-infusion. Secondary endpoints included objective response rate. ...Cytokine release syndrome was the most common adverse event, occurring in 26 (67%) …
The primary endpoint was the incidence of adverse events, defined as dose-limiting toxicities occurring within 28 days post-infusion. …
Occupational exposure to lithium-nickel-cobalt-manganese oxide materials in lithium battery: Health risks and mechanisms of toxicity.
Li X, Li N, Zhang X, Yu S. Li X, et al. Toxicol Ind Health. 2026 Apr;42(4):146-164. doi: 10.1177/07482337261433636. Epub 2026 Mar 17. Toxicol Ind Health. 2026. PMID: 41843943 Review.
This review critically evaluates current evidence on the occupational health effects of NCM materials across their life cycle, with particular emphasis on inhalation exposure to NCM particulates in manufacturing and recycling settings. ...Major adverse outcomes incl …
This review critically evaluates current evidence on the occupational health effects of NCM materials across their life cycle, …
Metal-on-Metal Hip Joint Prostheses: a Retrospective Case Series Investigating the Association of Systemic Toxicity with Serum Cobalt and Chromium Concentrations.
Ho JH, Leikin JB, Dargan PI, Archer JRH, Wood DM, Brent J. Ho JH, et al. J Med Toxicol. 2017 Dec;13(4):321-328. doi: 10.1007/s13181-017-0629-1. Epub 2017 Sep 12. J Med Toxicol. 2017. PMID: 28900863 Free PMC article.
INTRODUCTION: There have been concerns about prosthesis failure and the potential for systemic toxicity due to release of cobalt and chromium from metal-on-metal hip joint prostheses (MoM-HP). ...CONCLUSION: Two (6.5%) of 31 individuals referred for assessmen …
INTRODUCTION: There have been concerns about prosthesis failure and the potential for systemic toxicity due to release of c
Metals in cosmetics: implications for human health.
Borowska S, Brzóska MM. Borowska S, et al. J Appl Toxicol. 2015 Jun;35(6):551-72. doi: 10.1002/jat.3129. Epub 2015 Mar 23. J Appl Toxicol. 2015. PMID: 25809475 Review.
Cosmetics, preparations repeatedly applied directly to the human skin, mucous membranes, hair and nails, should be safe for health, however, recently there has been increasing concern about their safety. ...Some cases of topical (mainly allergic contact dermatitis) …
Cosmetics, preparations repeatedly applied directly to the human skin, mucous membranes, hair and nails, should be safe for health
43 results