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Year Number of Results
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1990 4
1991 4
1992 1
1993 3
1994 7
1995 1
1996 3
1997 5
1998 4
1999 5
2000 7
2001 7
2002 5
2003 10
2004 9
2005 11
2006 17
2007 24
2008 23
2009 28
2010 34
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2012 45
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2015 47
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2017 43
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633 results
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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Effect of cocoa on blood pressure.
Ried K, Fakler P, Stocks NP. Ried K, et al. Cochrane Database Syst Rev. 2017 Apr 25;4(4):CD008893. doi: 10.1002/14651858.CD008893.pub3. Cochrane Database Syst Rev. 2017. PMID: 28439881 Free PMC article. Review.
Here we update previous meta-analyses on the effect of cocoa on blood pressure. OBJECTIVES: To assess the effects on blood pressure of chocolate or cocoa products versus low-flavanol products or placebo in adults with or without hypertension when consumed for …
Here we update previous meta-analyses on the effect of cocoa on blood pressure. OBJECTIVES: To assess the effects on blood pressure o …
Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial.
Sesso HD, Manson JE, Aragaki AK, Rist PM, Johnson LG, Friedenberg G, Copeland T, Clar A, Mora S, Moorthy MV, Sarkissian A, Carrick WR, Anderson GL; COSMOS Research Group. Sesso HD, et al. Am J Clin Nutr. 2022 Jun 7;115(6):1490-1500. doi: 10.1093/ajcn/nqac055. Am J Clin Nutr. 2022. PMID: 35294962 Free PMC article. Clinical Trial.
OBJECTIVES: We examined whether cocoa extract supplementation decreases total cardiovascular disease (CVD) among older adults. ...The intervention phase was June 2015 through December 2020. This article reports on the cocoa extract intervention. Participants were ra …
OBJECTIVES: We examined whether cocoa extract supplementation decreases total cardiovascular disease (CVD) among older adults. ...The …
Consumption of 85% cocoa dark chocolate improves mood in association with gut microbial changes in healthy adults: a randomized controlled trial.
Shin JH, Kim CS, Cha L, Kim S, Lee S, Chae S, Chun WY, Shin DM. Shin JH, et al. J Nutr Biochem. 2022 Jan;99:108854. doi: 10.1016/j.jnutbio.2021.108854. Epub 2021 Sep 14. J Nutr Biochem. 2022. PMID: 34530112 Free article. Clinical Trial.
Dark chocolate has long been recognized for its mood-altering properties; however, the evidence regarding the emotional effects of daily dark chocolate intake is limited. ...Two different dark chocolates (85% and 70% cocoa content) were tested in this study. …
Dark chocolate has long been recognized for its mood-altering properties; however, the evidence regarding the emotional effects of da …
Neurocognitive Effects of Cocoa and Red-Berries Consumption in Healthy Adults.
García-Cordero J, Pino A, Cuevas C, Puertas-Martín V, San Román R, de Pascual-Teresa S. García-Cordero J, et al. Nutrients. 2021 Dec 21;14(1):1. doi: 10.3390/nu14010001. Nutrients. 2021. PMID: 35010877 Free PMC article. Clinical Trial.
A randomized, double-blind, parallel-group study was performed in 60 healthy volunteers between 50 and 75 years old who consumed a cocoa powder, a red berries mixture or a combination of both for 12 weeks. After the intervention, we observed a reduction in the time needed …
A randomized, double-blind, parallel-group study was performed in 60 healthy volunteers between 50 and 75 years old who consumed a cocoa …
Cocoa Flavanols Improve Vascular Responses to Acute Mental Stress in Young Healthy Adults.
Baynham R, Veldhuijzen van Zanten JJCS, Johns PW, Pham QS, Rendeiro C. Baynham R, et al. Nutrients. 2021 Mar 27;13(4):1103. doi: 10.3390/nu13041103. Nutrients. 2021. PMID: 33801767 Free PMC article. Clinical Trial.
Endothelial function (brachial flow-mediated dilatation, FMD) and brachial BP were measured before the intervention and 30 and 90 min post-stress. FMD was impaired 30 min post-stress, yet high-flavanol cocoa attenuated this decline and remained significantly higher compare …
Endothelial function (brachial flow-mediated dilatation, FMD) and brachial BP were measured before the intervention and 30 and 90 min post-s …
The effect of cocoa/dark chocolate consumption on lipid profile, glycemia, and blood pressure in diabetic patients: A meta-analysis of observational studies.
Darand M, Hajizadeh Oghaz M, Hadi A, Atefi M, Amani R. Darand M, et al. Phytother Res. 2021 Oct;35(10):5487-5501. doi: 10.1002/ptr.7183. Epub 2021 Jun 5. Phytother Res. 2021. PMID: 34089280 Review.
Pooled analysis indicated a significant reduction in low-density lipoprotein cholesterol LDL-c levels (WMD: -15.49 mg/dl; 95% CI: -24.56, -6.42, p = .001) and fasting blood sugar (FBS) concentrations (WMD: -6.88 mg/dl; 95% CI: -13.28, -0.48, p = .03) following cocoa/dark …
Pooled analysis indicated a significant reduction in low-density lipoprotein cholesterol LDL-c levels (WMD: -15.49 mg/dl; 95% CI: -24.56, -6 …
Gene expression changes by high-polyphenols cocoa powder intake: a randomized crossover clinical study.
Barrera-Reyes PK, Hernández-Ramírez N, Cortés J, Poquet L, Redeuil K, Rangel-Escareño C, Kussmann M, Silva-Zolezzi I, Tejero ME. Barrera-Reyes PK, et al. Eur J Nutr. 2019 Aug;58(5):1887-1898. doi: 10.1007/s00394-018-1736-8. Epub 2018 Jun 8. Eur J Nutr. 2019. PMID: 29948216 Free PMC article. Clinical Trial.
METHODS: A randomized, controlled, double-blind, cross-over, clinical trial in healthy young adults who consumed a single dose of high-polyphenols cocoa powder and maltodextrins as control, with a one-week washout period. ...A significant increase in circulating (-)-epicat …
METHODS: A randomized, controlled, double-blind, cross-over, clinical trial in healthy young adults who consumed a single dose of high-polyp …
Multivitamins in the prevention of cancer and cardiovascular disease: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial.
Sesso HD, Rist PM, Aragaki AK, Rautiainen S, Johnson LG, Friedenberg G, Copeland T, Clar A, Mora S, Moorthy MV, Sarkissian A, Wactawski-Wende J, Tinker LF, Carrick WR, Anderson GL, Manson JE; COSMOS Research Group. Sesso HD, et al. Am J Clin Nutr. 2022 Jun 7;115(6):1501-1510. doi: 10.1093/ajcn/nqac056. Am J Clin Nutr. 2022. PMID: 35294969 Free PMC article. Clinical Trial.
METHODS: We performed a randomized, double-blind, placebo-controlled, 2-by-2 factorial trial of a daily MVM and cocoa extract for prevention of cancer and cardiovascular disease (CVD) among 21,442 US adults (12,666 women aged 65 y and 8776 men aged 60 y) free of major CVD …
METHODS: We performed a randomized, double-blind, placebo-controlled, 2-by-2 factorial trial of a daily MVM and cocoa extract for pre …
Cocoa Flavanol Intake and Biomarkers for Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Lin X, Zhang I, Li A, Manson JE, Sesso HD, Wang L, Liu S. Lin X, et al. J Nutr. 2016 Nov;146(11):2325-2333. doi: 10.3945/jn.116.237644. Epub 2016 Sep 28. J Nutr. 2016. PMID: 27683874 Free PMC article. Review.
BACKGROUND: Cocoa flavanols may improve cardiometabolic health. Evidence from small short-term randomized clinical trials (RCTs) remains inconsistent, and large long-term RCTs testing the efficacy of cocoa flavanols are still lacking. ...Cocoa flavanol intake …
BACKGROUND: Cocoa flavanols may improve cardiometabolic health. Evidence from small short-term randomized clinical trials (RCTs) rema …
Impact of cocoa agricultural intensification on bird diversity and community composition.
Bennett RE, Sillett TS, Rice RA, Marra PP. Bennett RE, et al. Conserv Biol. 2022 Feb;36(1):e13779. doi: 10.1111/cobi.13779. Epub 2021 Aug 27. Conserv Biol. 2022. PMID: 34061388 Free PMC article.
To meet the growing demand for chocolate, cocoa (Theobroma cacao) agriculture is expanding and intensifying. Although this threatens tropical forests, cocoa sustainability initiatives largely overlook biodiversity conservation. ...
To meet the growing demand for chocolate, cocoa (Theobroma cacao) agriculture is expanding and intensifying. Although t …
633 results

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