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Year Number of Results
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1990 4
1991 4
1992 1
1993 3
1994 7
1995 1
1996 3
1997 5
1998 4
1999 5
2000 7
2001 7
2002 5
2003 10
2004 9
2005 11
2006 17
2007 24
2008 23
2009 28
2010 34
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703 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Consumption of 85% cocoa dark chocolate improves mood in association with gut microbial changes in healthy adults: a randomized controlled trial.
Shin JH, Kim CS, Cha J, Kim S, Lee S, Chae S, Chun WY, Shin DM. Shin JH, et al. J Nutr Biochem. 2022 Jan;99:108854. doi: 10.1016/j.jnutbio.2021.108854. Epub 2021 Sep 14. J Nutr Biochem. 2022. PMID: 34530112 Free article. Clinical Trial.
Dark chocolate has long been recognized for its mood-altering properties; however, the evidence regarding the emotional effects of daily dark chocolate intake is limited. ...Two different dark chocolates (85% and 70% cocoa content) were tested in this study. …
Dark chocolate has long been recognized for its mood-altering properties; however, the evidence regarding the emotional effects of da …
Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial.
Sesso HD, Manson JE, Aragaki AK, Rist PM, Johnson LG, Friedenberg G, Copeland T, Clar A, Mora S, Moorthy MV, Sarkissian A, Carrick WR, Anderson GL; COSMOS Research Group. Sesso HD, et al. Am J Clin Nutr. 2022 Jun 7;115(6):1490-1500. doi: 10.1093/ajcn/nqac055. Am J Clin Nutr. 2022. PMID: 35294962 Free PMC article. Clinical Trial.
OBJECTIVES: We examined whether cocoa extract supplementation decreases total cardiovascular disease (CVD) among older adults. ...The intervention phase was June 2015 through December 2020. This article reports on the cocoa extract intervention. Participants were ra …
OBJECTIVES: We examined whether cocoa extract supplementation decreases total cardiovascular disease (CVD) among older adults. ...The …
Effects of Cocoa Consumption on Cardiometabolic Risk Markers: Meta-Analysis of Randomized Controlled Trials.
Arisi TOP, da Silva DS, Stein E, Weschenfelder C, de Oliveira PC, Marcadenti A, Lehnen AM, Waclawovsky G. Arisi TOP, et al. Nutrients. 2024 Jun 18;16(12):1919. doi: 10.3390/nu16121919. Nutrients. 2024. PMID: 38931273 Free PMC article.
The eligible studies were randomized clinical trials (RCTs) involving adults undergoing cocoa consumption (cocoa extract or 70% cocoa dark chocolate) for 4 weeks that evaluated at least one of the following markers: body weight, body mass index (BMI), …
The eligible studies were randomized clinical trials (RCTs) involving adults undergoing cocoa consumption (cocoa extract or 70 …
Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial.
Baker LD, Manson JE, Rapp SR, Sesso HD, Gaussoin SA, Shumaker SA, Espeland MA. Baker LD, et al. Alzheimers Dement. 2023 Apr;19(4):1308-1319. doi: 10.1002/alz.12767. Epub 2022 Sep 14. Alzheimers Dement. 2023. PMID: 36102337 Free PMC article. Clinical Trial.
COSMOS-Mind tested whether daily administration of cocoa extract (containing 500 mg/day flavanols) versus placebo and a commercial multivitamin-mineral (MVM) versus placebo improved cognition in older women and men. ...Multivitamin-mineral benefits were also observed for m …
COSMOS-Mind tested whether daily administration of cocoa extract (containing 500 mg/day flavanols) versus placebo and a commercial mu …
Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS.
Vyas CM, Manson JE, Sesso HD, Cook NR, Rist PM, Weinberg A, Moorthy MV, Baker LD, Espeland MA, Yeung LK, Brickman AM, Okereke OI. Vyas CM, et al. Am J Clin Nutr. 2024 Mar;119(3):692-701. doi: 10.1016/j.ajcnut.2023.12.011. Epub 2024 Jan 18. Am J Clin Nutr. 2024. PMID: 38244989 Free PMC article.
OBJECTIVES: This study aimed to test MVM effects on cognitive change using in-person, detailed neuropsychological assessments and conduct a meta-analysis within COSMOS (COcoa Supplement and Multivitamin Outcomes Study) cognitive substudies for a robust evaluation of MVM ef …
OBJECTIVES: This study aimed to test MVM effects on cognitive change using in-person, detailed neuropsychological assessments and conduct a …
A clinical trial of the effects of cocoa rich chocolate on depression and sleep quality in menopausal women.
Abdoli E, Rezaie E, Mirghafourvand M, Payahoo L, Naseri E, Ghanbari-Homaie S. Abdoli E, et al. Sci Rep. 2024 Oct 14;14(1):23971. doi: 10.1038/s41598-024-74804-8. Sci Rep. 2024. PMID: 39397049 Free PMC article. Clinical Trial.
In this triple-blind, randomized clinical trial, 60 menopausal women between the ages of 45 and 65 were randomized to receive 78% dark chocolate (12 g/day) or milk chocolate (12 g/day) for eight weeks. The primary outcome was depression scores. ...ANCOVA with baseli …
In this triple-blind, randomized clinical trial, 60 menopausal women between the ages of 45 and 65 were randomized to receive 78% dark ch …
Does cocoa/dark chocolate supplementation have favorable effect on body weight, body mass index and waist circumference? A systematic review, meta-analysis and dose-response of randomized clinical trials.
Kord-Varkaneh H, Ghaedi E, Nazary-Vanani A, Mohammadi H, Shab-Bidar S. Kord-Varkaneh H, et al. Crit Rev Food Sci Nutr. 2019;59(15):2349-2362. doi: 10.1080/10408398.2018.1451820. Epub 2018 Apr 12. Crit Rev Food Sci Nutr. 2019. PMID: 29553824
Background: Cocoa and dark chocolate (DC) have been reported to be effective for health promotion; however the exact effect of cocoa/DC on anthropometric measures have not been yet defined. ...Subgroup analysis revealed that that weight and BMI were reduced w …
Background: Cocoa and dark chocolate (DC) have been reported to be effective for health promotion; however the exact effect of …
The effect of cocoa-rich products on depression, anxiety, and mood: A systematic review and meta-analysis.
Fusar-Poli L, Gabbiadini A, Ciancio A, Vozza L, Signorelli MS, Aguglia E. Fusar-Poli L, et al. Crit Rev Food Sci Nutr. 2022;62(28):7905-7916. doi: 10.1080/10408398.2021.1920570. Epub 2021 May 10. Crit Rev Food Sci Nutr. 2022. PMID: 33970709
In the popular imaginary, cocoa-derived products, like chocolate, represent a panacea for mood and affectivity. ...Our findings suggest that the consumption of cocoa-rich products may improve affect and mood in the short term. However, given the short duratio …
In the popular imaginary, cocoa-derived products, like chocolate, represent a panacea for mood and affectivity. ...Our finding …
Effect of dark chocolate/ cocoa consumption on oxidative stress and inflammation in adults: A GRADE-assessed systematic review and dose-response meta-analysis of controlled trials.
Behzadi M, Bideshki MV, Ahmadi-Khorram M, Zarezadeh M, Hatami A. Behzadi M, et al. Complement Ther Med. 2024 Sep;84:103061. doi: 10.1016/j.ctim.2024.103061. Epub 2024 Jun 24. Complement Ther Med. 2024. PMID: 38925412 Free article.
BACKGROUND: Oxidative stress and inflammation play critical roles in the pathogenesis of many chronic diseases. Dark chocolate (DC)/cocoa, as a rich source of polyphenols like flavonoids, has anti-inflammatory and antioxidant properties that may confer health benefi …
BACKGROUND: Oxidative stress and inflammation play critical roles in the pathogenesis of many chronic diseases. Dark chocolate (DC)/ …
Effect of cocoa on blood pressure.
Ried K, Fakler P, Stocks NP. Ried K, et al. Cochrane Database Syst Rev. 2017 Apr 25;4(4):CD008893. doi: 10.1002/14651858.CD008893.pub3. Cochrane Database Syst Rev. 2017. PMID: 28439881 Free PMC article.
Here we update previous meta-analyses on the effect of cocoa on blood pressure. OBJECTIVES: To assess the effects on blood pressure of chocolate or cocoa products versus low-flavanol products or placebo in adults with or without hypertension when consumed for …
Here we update previous meta-analyses on the effect of cocoa on blood pressure. OBJECTIVES: To assess the effects on blood pressure o …
703 results