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785 results

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Page 1
Colchicine in Pericarditis.
Bayes-Genis A, Adler Y, de Luna AB, Imazio M. Bayes-Genis A, et al. Eur Heart J. 2017 Jun 7;38(22):1706-1709. doi: 10.1093/eurheartj/ehx246. Eur Heart J. 2017. PMID: 30052886 Review. No abstract available.
Diagnosis, Risk Stratification, and Treatment of Pericarditis: A Review.
Cremer PC, Klein AL, Imazio M. Cremer PC, et al. JAMA. 2024 Oct 1;332(13):1090-1100. doi: 10.1001/jama.2024.12935. JAMA. 2024. PMID: 39235771 Review.
In North America and Western Europe, the most common causes of acute pericarditis are idiopathic or viral, followed by pericarditis after cardiac procedures or operations. ...With a first recurrence of pericarditis, colchicine should be continued for a …
In North America and Western Europe, the most common causes of acute pericarditis are idiopathic or viral, followed by pericarditi …
Colchicine for pericarditis.
Alabed S, Cabello JB, Irving GJ, Qintar M, Burls A. Alabed S, et al. Cochrane Database Syst Rev. 2014 Aug 28;2014(8):CD010652. doi: 10.1002/14651858.CD010652.pub2. Cochrane Database Syst Rev. 2014. PMID: 25164988 Free PMC article.
Two comparable trials studied the effects of colchicine in 204 participants with recurrent pericarditis and two trials studied 360 people with acute pericarditis. ...AUTHORS' CONCLUSIONS: Colchicine, as adjunctive therapy to NSAIDs, is effective in red …
Two comparable trials studied the effects of colchicine in 204 participants with recurrent pericarditis and two trials studied …
A randomized trial of colchicine for acute pericarditis.
Imazio M, Brucato A, Cemin R, Ferrua S, Maggiolini S, Beqaraj F, Demarie D, Forno D, Ferro S, Maestroni S, Belli R, Trinchero R, Spodick DH, Adler Y; ICAP Investigators. Imazio M, et al. N Engl J Med. 2013 Oct 17;369(16):1522-8. doi: 10.1056/NEJMoa1208536. Epub 2013 Aug 31. N Engl J Med. 2013. PMID: 23992557 Free article. Clinical Trial.
BACKGROUND: Colchicine is effective for the treatment of recurrent pericarditis. However, conclusive data are lacking regarding the use of colchicine during a first attack of acute pericarditis and in the prevention of recurrent symptoms. ...CONCLUSION …
BACKGROUND: Colchicine is effective for the treatment of recurrent pericarditis. However, conclusive data are lacking regardin …
Colchicine in Cardiovascular Disease: In-Depth Review.
Deftereos SG, Beerkens FJ, Shah B, Giannopoulos G, Vrachatis DA, Giotaki SG, Siasos G, Nicolas J, Arnott C, Patel S, Parsons M, Tardif JC, Kovacic JC, Dangas GD. Deftereos SG, et al. Circulation. 2022 Jan 4;145(1):61-78. doi: 10.1161/CIRCULATIONAHA.121.056171. Epub 2021 Dec 29. Circulation. 2022. PMID: 34965168 Free PMC article. Review.
We aim to summarize colchicine's pharmacodynamics and the mechanism behind its anti-inflammatory effect, outline thus far accumulated evidence on treatment with colchicine in cardiovascular disease, and present ongoing randomized clinical trials. We also emph …
We aim to summarize colchicine's pharmacodynamics and the mechanism behind its anti-inflammatory effect, outline thus far accu …
Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction.
Tardif JC, Kouz S, Waters DD, Bertrand OF, Diaz R, Maggioni AP, Pinto FJ, Ibrahim R, Gamra H, Kiwan GS, Berry C, López-Sendón J, Ostadal P, Koenig W, Angoulvant D, Grégoire JC, Lavoie MA, Dubé MP, Rhainds D, Provencher M, Blondeau L, Orfanos A, L'Allier PL, Guertin MC, Roubille F. Tardif JC, et al. N Engl J Med. 2019 Dec 26;381(26):2497-2505. doi: 10.1056/NEJMoa1912388. Epub 2019 Nov 16. N Engl J Med. 2019. PMID: 31733140 Free article. Clinical Trial.
BACKGROUND: Experimental and clinical evidence supports the role of inflammation in atherosclerosis and its complications. Colchicine is an orally administered, potent antiinflammatory medication that is indicated for the treatment of gout and pericarditis. ...Diarr …
BACKGROUND: Experimental and clinical evidence supports the role of inflammation in atherosclerosis and its complications. Colchicine …
Colchicine for pericarditis.
Imazio M. Imazio M. Trends Cardiovasc Med. 2015 Feb;25(2):129-36. doi: 10.1016/j.tcm.2014.09.011. Epub 2014 Oct 2. Trends Cardiovasc Med. 2015. PMID: 25454379 Review.
Colchicine is one of the oldest available drugs. It has been used for centuries to treat and prevent gouty attacks and more recently to prevent attacks of autoinflammatory diseases such as Familial Mediterranean Fever. ...The capability to concentrate in white blood cells, …
Colchicine is one of the oldest available drugs. It has been used for centuries to treat and prevent gouty attacks and more recently …
Anakinra for corticosteroid-dependent and colchicine-resistant pericarditis: The IRAP (International Registry of Anakinra for Pericarditis) study.
Imazio M, Andreis A, De Ferrari GM, Cremer PC, Mardigyan V, Maestroni S, Luis SA, Lopalco G, Emmi G, Lotan D, Marcolongo R, Lazaros G, De Biasio M, Cantarini L, Dagna L, Cercek AC, Pivetta E, Varma B, Berkson L, Tombetti E, Iannone F, Prisco D, Caforio ALP, Vassilopoulos D, Tousoulis D, De Luca G, Giustetto C, Rinaldi M, Oh JK, Klein AL, Brucato A, Adler Y. Imazio M, et al. Eur J Prev Cardiol. 2020 Jun;27(9):956-964. doi: 10.1177/2047487319879534. Epub 2019 Oct 15. Eur J Prev Cardiol. 2020. PMID: 31610707 Free article.
AIMS: Novel therapies are needed for recurrent pericarditis, particularly when corticosteroid dependent and colchicine resistant. Based on limited data, interleukin-1 blockade with anakinra may be beneficial. ...METHODS AND RESULTS: This registry enrolled consecutiv …
AIMS: Novel therapies are needed for recurrent pericarditis, particularly when corticosteroid dependent and colchicine resista …
Evaluation and Treatment of Pericarditis: A Systematic Review.
Imazio M, Gaita F, LeWinter M. Imazio M, et al. JAMA. 2015 Oct 13;314(14):1498-506. doi: 10.1001/jama.2015.12763. JAMA. 2015. PMID: 26461998
The most common treatment for idiopathic and viral pericarditis in North America and Europe is NSAID therapy. Adjunctive colchicine can ameliorate the initial episode and is associated with approximately 50% lower recurrence rates. ...Appropriate triage and treatmen …
The most common treatment for idiopathic and viral pericarditis in North America and Europe is NSAID therapy. Adjunctive colchicin …
Colchicine and the heart.
Imazio M, Nidorf M. Imazio M, et al. Eur Heart J. 2021 Jul 21;42(28):2745-2760. doi: 10.1093/eurheartj/ehab221. Eur Heart J. 2021. PMID: 33961006 Free PMC article. Review.
Colchicine is a unique, sophisticated anti-inflammatory agent that has been used for decades for the prevention of acute inflammatory flares in gout and familial Mediterranean fever. ...In patients with acute and recurrent pericarditis, clinical trials in >1600 p …
Colchicine is a unique, sophisticated anti-inflammatory agent that has been used for decades for the prevention of acute inflammatory …
785 results