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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1902 2
1914 1
1923 1
1929 1
1931 2
1932 2
1933 1
1938 2
1940 2
1942 1
1944 1
1945 8
1946 1
1947 12
1948 11
1949 23
1950 40
1951 67
1952 74
1953 108
1954 93
1955 133
1956 150
1957 152
1958 171
1959 143
1960 176
1961 224
1962 234
1963 404
1964 578
1965 370
1966 261
1967 290
1968 327
1969 324
1970 352
1971 330
1972 410
1973 403
1974 441
1975 997
1976 984
1977 965
1978 1023
1979 1063
1980 1246
1981 1289
1982 1375
1983 1586
1984 1789
1985 1837
1986 2021
1987 1994
1988 2248
1989 2599
1990 2783
1991 2930
1992 3061
1993 3092
1994 3157
1995 3328
1996 3445
1997 3473
1998 3472
1999 3689
2000 3810
2001 3976
2002 4186
2003 4508
2004 4878
2005 5388
2006 5615
2007 5958
2008 6362
2009 6567
2010 7192
2011 7790
2012 8169
2013 8734
2014 8986
2015 9323
2016 9218
2017 9444
2018 9506
2019 9698
2020 9456
2021 42
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192,879 results
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Page 1
The role of collagen in cancer: from bench to bedside.
Xu S, Xu H, Wang W, Li S, Li H, Li T, Zhang W, Yu X, Liu L. Xu S, et al. J Transl Med. 2019 Sep 14;17(1):309. doi: 10.1186/s12967-019-2058-1. J Transl Med. 2019. PMID: 31521169 Free PMC article. Review.
Collagen is the major component of the tumor microenvironment and participates in cancer fibrosis. ...Exosomes and microRNAs are closely associated with collagen in cancer. Hypoxia, which is common in collagen-rich conditions, intensifies cancer progression,
Collagen is the major component of the tumor microenvironment and participates in cancer fibrosis. ...Exosomes and microRNAs are clos
The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials.
Asserin J, Lati E, Shioya T, Prawitt J. Asserin J, et al. J Cosmet Dermatol. 2015 Dec;14(4):291-301. doi: 10.1111/jocd.12174. Epub 2015 Sep 12. J Cosmet Dermatol. 2015. PMID: 26362110 Clinical Trial.
Our aim was to investigate the effect of oral supplementation with specific collagen peptides on skin hydration and the dermal collagen network in a clinical setting. METHODS: Two placebo-controlled clinical trials were run to assess the effect of a daily oral suppl …
Our aim was to investigate the effect of oral supplementation with specific collagen peptides on skin hydration and the dermal col
Collagen structure: new tricks from a very old dog.
Bella J. Bella J. Biochem J. 2016 Apr 15;473(8):1001-25. doi: 10.1042/BJ20151169. Biochem J. 2016. PMID: 27060106 Review.
High-resolution crystal structures from collagen model peptides have provided a wealth of data on collagen conformational variability, interaction with water, collagen stability or the effects of interruptions. ...In recent years, collagen biochemistry …
High-resolution crystal structures from collagen model peptides have provided a wealth of data on collagen conformational vari …
Novel Biomedical Applications of Crosslinked Collagen.
Gu L, Shan T, Ma YX, Tay FR, Niu L. Gu L, et al. Trends Biotechnol. 2019 May;37(5):464-491. doi: 10.1016/j.tibtech.2018.10.007. Epub 2018 Nov 14. Trends Biotechnol. 2019. PMID: 30447877 Review.
Collagen is one of the most useful biopolymers because of its low immunogenicity and biocompatibility. ...Understanding the role of crosslinking agents in the modification of collagen performance and their potential biomedical applications are crucial for developing
Collagen is one of the most useful biopolymers because of its low immunogenicity and biocompatibility. ...Understanding the role of c
What is the role of peptide fragments of collagen I and IV in health and disease?
Kisling A, Lust RM, Katwa LC. Kisling A, et al. Life Sci. 2019 Jul 1;228:30-34. doi: 10.1016/j.lfs.2019.04.042. Epub 2019 Apr 17. Life Sci. 2019. PMID: 31004660 Review.
Collagen provides the necessary structural framework for tissues in which it is found. ...The collagen peptides of interest are those generated from the primary collagen type of tissue interstitial matrix, collagen type I, and the basement membrane,
Collagen provides the necessary structural framework for tissues in which it is found. ...The collagen peptides of interest ar
The influence of age and sex on skin thickness, skin collagen and density.
Shuster S, Black MM, McVitie E. Shuster S, et al. Br J Dermatol. 1975 Dec;93(6):639-43. doi: 10.1111/j.1365-2133.1975.tb05113.x. Br J Dermatol. 1975. PMID: 1220811
Forearm skin collagen, dermal thickness and collagen density were measured in a large number of normal subjects as a standard reference for future studies. ...There is a direct relationship between skin collagen and dermal thickness but variations in colla
Forearm skin collagen, dermal thickness and collagen density were measured in a large number of normal subjects as a standard …
Type I Collagen Purification from Rat Tail Tendons.
Rittié L. Rittié L. Methods Mol Biol. 2017;1627:287-308. doi: 10.1007/978-1-4939-7113-8_19. Methods Mol Biol. 2017. PMID: 28836209
All these in vitro models rely on utilizing high-quality purified collagen I. Here, we provide state-of-the-art collagen I extraction protocol and useful tips to produce high-quality purified collagen I solutions. We also provide a detailed protocol for pepsi …
All these in vitro models rely on utilizing high-quality purified collagen I. Here, we provide state-of-the-art collagen I ext …
Medical Applications of Collagen and Collagen-Based Materials.
Shekhter AB, Fayzullin AL, Vukolova MN, Rudenko TG, Osipycheva VD, Litvitsky PF. Shekhter AB, et al. Curr Med Chem. 2019;26(3):506-516. doi: 10.2174/0929867325666171205170339. Curr Med Chem. 2019. PMID: 29210638 Review.
Collagen and collagen-based materials have been successfully used in medicine for over 50 years. ...The review contains materials about historic and modern applications of collagen in medicine such as soluble collagen injections, solid constructs recon
Collagen and collagen-based materials have been successfully used in medicine for over 50 years. ...The review contains materi
The role of collagen in bone strength.
Viguet-Carrin S, Garnero P, Delmas PD. Viguet-Carrin S, et al. Osteoporos Int. 2006;17(3):319-36. doi: 10.1007/s00198-005-2035-9. Epub 2005 Dec 9. Osteoporos Int. 2006. PMID: 16341622 Review.
This review describes the interactions of type I collagen with the mineral and the contribution of the orientations of the collagen fibers when the bone is submitted to mechanical forces. ...These modifications of collagen are age-related and may impair the m …
This review describes the interactions of type I collagen with the mineral and the contribution of the orientations of the collage
Targeting collagen for diagnostic imaging and therapeutic delivery.
Wahyudi H, Reynolds AA, Li Y, Owen SC, Yu SM. Wahyudi H, et al. J Control Release. 2016 Oct 28;240:323-331. doi: 10.1016/j.jconrel.2016.01.007. Epub 2016 Jan 7. J Control Release. 2016. PMID: 26773768 Free PMC article. Review.
Collagen remodeling can lead to either an overproduction of collagen which can cause excessive collagen accumulation in organs, common to fibrosis, or uncontrolled degradation of collagen seen in degenerative diseases such as arthritis. ...It aims to h
Collagen remodeling can lead to either an overproduction of collagen which can cause excessive collagen accumulation in
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