Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 1
1978 1
1980 1
1981 1
1982 1
1983 2
1984 5
1985 1
1986 3
1987 2
1988 7
1989 3
1990 1
1991 3
1992 3
1993 7
1994 7
1995 8
1996 4
1997 8
1998 6
1999 4
2000 7
2001 7
2002 18
2003 10
2004 20
2005 11
2006 22
2007 18
2008 23
2009 20
2010 33
2011 34
2012 31
2013 34
2014 34
2015 36
2016 30
2017 28
2018 32
2019 28
2020 31
2021 40
2022 19
2023 28
2024 25
2025 27
2026 14

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

657 results

Results by year

Filters applied: . Clear all
Page 1
Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study.
Lugo JP, Saiyed ZM, Lane NE. Lugo JP, et al. Nutr J. 2016 Jan 29;15:14. doi: 10.1186/s12937-016-0130-8. Nutr J. 2016. PMID: 26822714 Free PMC article. Clinical Trial.
BACKGROUND: Undenatured type II collagen (UC-II) is a nutritional supplement derived from chicken sternum cartilage. The purpose of this study was to evaluate the efficacy and tolerability of UC-II for knee osteoarthritis (OA) pain and associated symptoms com …
BACKGROUND: Undenatured type II collagen (UC-II) is a nutritional supplement derived from chicken sternum cartilage. Th …
24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain.
Clark KL, Sebastianelli W, Flechsenhar KR, Aukermann DF, Meza F, Millard RL, Deitch JR, Sherbondy PS, Albert A. Clark KL, et al. Curr Med Res Opin. 2008 May;24(5):1485-96. doi: 10.1185/030079908x291967. Epub 2008 Apr 15. Curr Med Res Opin. 2008. PMID: 18416885 Clinical Trial.
BACKGROUND: Collagen hydrolysate is a nutritional supplement that has been shown to exert an anabolic effect on cartilage tissue. ...CONCLUSION: This was the first clinical trial of 24-weeks duration to show improvement of joint pain in athletes who were trea …
BACKGROUND: Collagen hydrolysate is a nutritional supplement that has been shown to exert an anabolic effect on cartilage …
Mechanism of Action of Collagen and Epidermal Growth Factor: A Review on Theory and Research Methods.
Shahrajabian MH, Sun W. Shahrajabian MH, et al. Mini Rev Med Chem. 2024;24(4):453-477. doi: 10.2174/1389557523666230816090054. Mini Rev Med Chem. 2024. PMID: 37587815 Review.
Fibrillar collagens are collagen types I, II, III, V, XI, XXIV, XXVII, and non-fibrillar collagens are collagen types IV, VI, VII, VIII, IX, X, XII, XIII, XIV, XV, XVI, XVII, XVIII, XIX, XX, XXI, XXII, XXIII, XXV, XXVI, XXVIII, and XXIX. Collagen …
Fibrillar collagens are collagen types I, II, III, V, XI, XXIV, XXVII, and non-fibrillar collagens are collagen …
Collagen: A review on its sources and potential cosmetic applications.
Avila Rodríguez MI, Rodríguez Barroso LG, Sánchez ML. Avila Rodríguez MI, et al. J Cosmet Dermatol. 2018 Feb;17(1):20-26. doi: 10.1111/jocd.12450. Epub 2017 Nov 16. J Cosmet Dermatol. 2018. PMID: 29144022 Review.
Collagen is a fibrillar protein that conforms the conjunctive and connective tissues in the human body, essentially skin, joints, and bones. ...As a solution, the cosmetic industry incorporated collagen as an ingredient of different treatments to enhance the user yo …
Collagen is a fibrillar protein that conforms the conjunctive and connective tissues in the human body, essentially skin, joints, and …
Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature.
Bello AE, Oesser S. Bello AE, et al. Curr Med Res Opin. 2006 Nov;22(11):2221-32. doi: 10.1185/030079906X148373. Curr Med Res Opin. 2006. PMID: 17076983 Review.
SCOPE: This article reviews the medical literature on the preclinical and clinical research on a unique compound, collagen hydrolysate. Articles were obtained through searches of the PubMed database (www.pubmed.gov) through May 2006 using several pairs of key words (col …
SCOPE: This article reviews the medical literature on the preclinical and clinical research on a unique compound, collagen hydrolysat …
[An overview of the beneficial effects of hydrolysed collagen intake on joint and bone health and on skin ageing].
Figueres Juher T, Basés Pérez E. Figueres Juher T, et al. Nutr Hosp. 2015 Jul 18;32 Suppl 1:62-6. doi: 10.3305/nh.2015.32.sup1.9482. Nutr Hosp. 2015. PMID: 26267777 Free article. Review. Spanish.
INTRODUCTION: Hydrolysate Collagen (HC) consists of small peptides with a molecular weight lower than 5.000 Da. produced from gelatinization and subsequent enzymatic hydrolysis of native collagen which is found in rich collagenic animal tissues. ...CONCLUSION …
INTRODUCTION: Hydrolysate Collagen (HC) consists of small peptides with a molecular weight lower than 5.000 Da. produced from gelatin …
Efficacy of undenatured collagen in knee osteoarthritis: review of the literature with limited meta-analysis.
Kumar P, Bansal P, Rajnish RK, Sharma S, Dhillon MS, Patel S, Kumar V. Kumar P, et al. Am J Transl Res. 2023 Sep 15;15(9):5545-5555. eCollection 2023. Am J Transl Res. 2023. PMID: 37854210 Free PMC article. Review.
Undenatured collagen type II (UC-II) has been introduced for therapy in early OA; it helps in cartilage repair and preservation. ...The overall complications were similar to other supplements. CONCLUSION: With limited literature, UC-II has shown promise as a …
Undenatured collagen type II (UC-II) has been introduced for therapy in early OA; it helps in cartilage repair and preservatio …
Roles of dietary glycine, proline, and hydroxyproline in collagen synthesis and animal growth.
Li P, Wu G. Li P, et al. Amino Acids. 2018 Jan;50(1):29-38. doi: 10.1007/s00726-017-2490-6. Epub 2017 Sep 20. Amino Acids. 2018. PMID: 28929384 Review.
Glycine, proline, and hydroxyproline (Hyp) contribute to 57% of total amino acids (AAs) in collagen, which accounts for one-third of proteins in animals. As the most abundant protein in the body, collagen is essential to maintain the normal structure and strength of …
Glycine, proline, and hydroxyproline (Hyp) contribute to 57% of total amino acids (AAs) in collagen, which accounts for one-third of …
Nutraceutical Approach to Chronic Osteoarthritis: From Molecular Research to Clinical Evidence.
Colletti A, Cicero AFG. Colletti A, et al. Int J Mol Sci. 2021 Nov 29;22(23):12920. doi: 10.3390/ijms222312920. Int J Mol Sci. 2021. PMID: 34884724 Free PMC article. Review.
Osteoarthritis (OA) is a degenerative inflammatory condition of the joint cartilage that currently affects approximately 58 million adults in the world. It is characterized by pain, stiffness, and a reduced range of motion with regard to the arthritic joints. ...Although t …
Osteoarthritis (OA) is a degenerative inflammatory condition of the joint cartilage that currently affects approximately 58 million a …
Undenatured type II collagen for knee osteoarthritis.
Gupta A, Maffulli N. Gupta A, et al. Ann Med. 2025 Dec;57(1):2493306. doi: 10.1080/07853890.2025.2493306. Epub 2025 Apr 20. Ann Med. 2025. PMID: 40253594 Free PMC article. Review.
The use of nutraceuticals, including native/undenatured type II collagen (UC-2), has evolved and shown promise in the conservative management of knee OA. ...DISCUSSION: UC-2 acts via a specific immune mediated mechanism, known as oral tolerance, which can lead to reduced i …
The use of nutraceuticals, including native/undenatured type II collagen (UC-2), has evolved and shown promise in the conservative ma …
657 results