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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
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1963 2
1964 1
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1972 2
1973 3
1974 1
1975 3
1976 4
1977 5
1978 4
1979 7
1980 6
1981 3
1982 18
1983 13
1984 10
1985 8
1986 18
1987 21
1988 13
1989 27
1990 25
1991 38
1992 41
1993 32
1994 39
1995 50
1996 57
1997 45
1998 45
1999 44
2000 47
2001 54
2002 43
2003 40
2004 42
2005 48
2006 42
2007 48
2008 54
2009 59
2010 54
2011 51
2012 68
2013 68
2014 83
2015 84
2016 74
2017 88
2018 75
2019 89
2020 135
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2025 179
2026 188

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2,569 results

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Page 1
Collateral sensitivity of natural products in drug-resistant cancer cells.
Efferth T, Saeed MEM, Kadioglu O, Seo EJ, Shirooie S, Mbaveng AT, Nabavi SM, Kuete V. Efferth T, et al. Biotechnol Adv. 2020 Jan-Feb;38:107342. doi: 10.1016/j.biotechadv.2019.01.009. Epub 2019 Jan 29. Biotechnol Adv. 2020. PMID: 30708024 Review.
However, tumors may be specifically hypersensitive to other drugs - a phenomenon also termed collateral sensitivity. This seems to be a general biological mechanism, since it also occurs in drug-resistant Escherichia coli and Saccharomyces cerevisiae. ...Resi …
However, tumors may be specifically hypersensitive to other drugs - a phenomenon also termed collateral sensitivity. This seem …
Collateral sensitivity and genetic vulnerability of antibiotic resistance.
Yang K, Rasouly A, Nudler E. Yang K, et al. Trends Microbiol. 2026 Apr;34(4):419-430. doi: 10.1016/j.tim.2025.11.002. Epub 2025 Dec 2. Trends Microbiol. 2026. PMID: 41339140 Review.
Antibiotic combination therapy has a critical role in limiting emergent antibiotic resistance in bacterial pathogens. Collateral sensitivity (CS), resistance to one antibiotic that is inextricable from sensitivity to another antibiotic, presents an opportunit …
Antibiotic combination therapy has a critical role in limiting emergent antibiotic resistance in bacterial pathogens. Collateral s …
Collateral sensitivity of antibiotic-resistant microbes.
Pál C, Papp B, Lázár V. Pál C, et al. Trends Microbiol. 2015 Jul;23(7):401-7. doi: 10.1016/j.tim.2015.02.009. Epub 2015 Mar 25. Trends Microbiol. 2015. PMID: 25818802 Free PMC article. Review.
Strikingly, mutations that caused multidrug resistance in bacteria simultaneously enhanced sensitivity to many other unrelated drugs (collateral sensitivity). Here, we explore how this emerging research sheds new light on resistance mechanisms and the way it …
Strikingly, mutations that caused multidrug resistance in bacteria simultaneously enhanced sensitivity to many other unrelated drugs …
Anticancer Natural Products with Collateral Sensitivity: A Review.
Qian J, Cui J, Li S, Chen J, Jia J. Qian J, et al. Mini Rev Med Chem. 2021;21(12):1465-1486. doi: 10.2174/1389557521666210112141455. Mini Rev Med Chem. 2021. PMID: 33438535 Review.
The research and development of new drug candidates with collateral sensitivity will be an efficient approach to conquer multidrug resistance in cancer. ...The exploration of molecular mechanisms of collateral sensitivity and structural features …
The research and development of new drug candidates with collateral sensitivity will be an efficient approach to conque …
Navigating collateral sensitivity: insights into the mechanisms and applications of antibiotic resistance trade-offs.
Mahmud HA, Wakeman CA. Mahmud HA, et al. Front Microbiol. 2024 Oct 24;15:1478789. doi: 10.3389/fmicb.2024.1478789. eCollection 2024. Front Microbiol. 2024. PMID: 39512935 Free PMC article. Review.
The swift rise of antibiotic resistance, coupled with limited new antibiotic discovery, presents a significant hurdle to global public health, demanding innovative therapeutic solutions. Recently, collateral sensitivity (CS), the phenomenon in which resistance to on …
The swift rise of antibiotic resistance, coupled with limited new antibiotic discovery, presents a significant hurdle to global public healt …
Collateral Sensitivity to beta-Lactam Antibiotics in Evolved Apramycin-Resistant MRSA.
Wu J, Wu S, Liu J, Li C, Zheng M, Li F, Zhang Y, Wu Y, Yu Y. Wu J, et al. Int J Mol Sci. 2024 Nov 15;25(22):12292. doi: 10.3390/ijms252212292. Int J Mol Sci. 2024. PMID: 39596355 Free PMC article.
Collateral sensitivity is an evolutionary trade-off for bacteria where acquiring resistance to one antibiotic results in an increased sensitivity to another antibiotic. ...These results provide new insights into collateral sensitivity-based stra …
Collateral sensitivity is an evolutionary trade-off for bacteria where acquiring resistance to one antibiotic results in an in …
Collateral sensitivity to pleuromutilins in vancomycin-resistant Enterococcus faecium.
Li Q, Chen S, Zhu K, Huang X, Huang Y, Shen Z, Ding S, Gu D, Yang Q, Sun H, Hu F, Wang H, Cai J, Ma B, Zhang R, Shen J. Li Q, et al. Nat Commun. 2022 Apr 7;13(1):1888. doi: 10.1038/s41467-022-29493-0. Nat Commun. 2022. PMID: 35393429 Free PMC article.
The acquisition of resistance to one antibiotic sometimes leads to collateral sensitivity to a second antibiotic. Here, we show that vancomycin resistance in Enterococcus faecium is associated with a remarkable increase in susceptibility to pleuromutilin antibiotics …
The acquisition of resistance to one antibiotic sometimes leads to collateral sensitivity to a second antibiotic. Here, we sho …
Collateral sensitivity associated with antibiotic resistance plasmids.
Herencias C, Rodríguez-Beltrán J, León-Sampedro R, Alonso-Del Valle A, Palkovičová J, Cantón R, San Millán Á. Herencias C, et al. Elife. 2021 Jan 20;10:e65130. doi: 10.7554/eLife.65130. Elife. 2021. PMID: 33470194 Free PMC article.
Collateral sensitivity (CS) is a promising alternative approach to counteract the rising problem of antibiotic resistance (ABR). ...
Collateral sensitivity (CS) is a promising alternative approach to counteract the rising problem of antibiotic resistance (ABR …
Collateral Sensitivity Interactions between Antibiotics Depend on Local Abiotic Conditions.
Allen RC, Pfrunder-Cardozo KR, Hall AR. Allen RC, et al. mSystems. 2021 Dec 21;6(6):e0105521. doi: 10.1128/mSystems.01055-21. Epub 2021 Nov 30. mSystems. 2021. PMID: 34846167 Free PMC article.
Mutations conferring resistance to one antibiotic can increase (cross-resistance) or decrease (collateral sensitivity) resistance to others. Antibiotic combinations displaying collateral sensitivity could be used in treatments that slow resistance evol …
Mutations conferring resistance to one antibiotic can increase (cross-resistance) or decrease (collateral sensitivity) resista …
The population genetics of collateral resistance and sensitivity.
Ardell SM, Kryazhimskiy S. Ardell SM, et al. Elife. 2021 Dec 10;10:e73250. doi: 10.7554/eLife.73250. Elife. 2021. PMID: 34889185 Free PMC article.
Resistance mutations against one drug can elicit collateral sensitivity against other drugs. Multi-drug treatments exploiting such trade-offs can help slow down the evolution of resistance. However, if mutations with diverse collateral effects a …
Resistance mutations against one drug can elicit collateral sensitivity against other drugs. Multi-drug treatmen …
2,569 results