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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2000 1
2001 1
2002 1
2004 2
2005 2
2006 3
2007 4
2008 2
2009 3
2010 3
2011 3
2012 4
2013 4
2014 3
2015 6
2016 6
2017 2
2018 6
2019 4
2020 3
2021 2
2022 9
2023 4
2024 3

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72 results

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8 articles found by citation matching
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Page 1
Acetylation of Cytidine in mRNA Promotes Translation Efficiency.
Arango D, Sturgill D, Alhusaini N, Dillman AA, Sweet TJ, Hanson G, Hosogane M, Sinclair WR, Nanan KK, Mandler MD, Fox SD, Zengeya TT, Andresson T, Meier JL, Coller J, Oberdoerffer S. Arango D, et al. Among authors: coller j. Cell. 2018 Dec 13;175(7):1872-1886.e24. doi: 10.1016/j.cell.2018.10.030. Epub 2018 Nov 15. Cell. 2018. PMID: 30449621 Free PMC article.
Generation of the "epitranscriptome" through post-transcriptional ribonucleoside modification embeds a layer of regulatory complexity into RNA structure and function. Here, we describe N4-acetylcytidine (ac4C) as an mRNA modification that is catalyzed by the acetyltransfer …
Generation of the "epitranscriptome" through post-transcriptional ribonucleoside modification embeds a layer of regulatory complexity into …
Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis.
Wirka RC, Wagh D, Paik DT, Pjanic M, Nguyen T, Miller CL, Kundu R, Nagao M, Coller J, Koyano TK, Fong R, Woo YJ, Liu B, Montgomery SB, Wu JC, Zhu K, Chang R, Alamprese M, Tallquist MD, Kim JB, Quertermous T. Wirka RC, et al. Among authors: coller j. Nat Med. 2019 Aug;25(8):1280-1289. doi: 10.1038/s41591-019-0512-5. Epub 2019 Jul 29. Nat Med. 2019. PMID: 31359001 Free PMC article.
However, the phenotype of modulated SMCs in vivo during atherosclerosis and the influence of this process on coronary artery disease (CAD) risk have not been clearly established. Using single-cell RNA sequencing, we comprehensively characterized the transcriptomic phenotyp …
However, the phenotype of modulated SMCs in vivo during atherosclerosis and the influence of this process on coronary artery disease (CAD) r …
Computational design of mRNA vaccines.
Kim YA, Mousavi K, Yazdi A, Zwierzyna M, Cardinali M, Fox D, Peel T, Coller J, Aggarwal K, Maruggi G. Kim YA, et al. Among authors: coller j. Vaccine. 2024 Mar 7;42(7):1831-1840. doi: 10.1016/j.vaccine.2023.07.024. Epub 2023 Jul 20. Vaccine. 2024. PMID: 37479613 Review.
Accumulating evidence shows that vaccine efficacy, thermostability, and other important properties, are largely impacted by intrinsic properties of the mRNA molecule, such as RNA sequence and structure, both of which can be optimized. Designing mRNA sequence for vaccines p …
Accumulating evidence shows that vaccine efficacy, thermostability, and other important properties, are largely impacted by intrinsic proper …
tRNA therapeutics for genetic diseases.
Coller J, Ignatova Z. Coller J, et al. Nat Rev Drug Discov. 2024 Feb;23(2):108-125. doi: 10.1038/s41573-023-00829-9. Epub 2023 Dec 4. Nat Rev Drug Discov. 2024. PMID: 38049504 Review.
Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin.
Foster DS, Januszyk M, Delitto D, Yost KE, Griffin M, Guo J, Guardino N, Delitto AE, Chinta M, Burcham AR, Nguyen AT, Bauer-Rowe KE, Titan AL, Salhotra A, Jones RE, da Silva O, Lindsay HG, Berry CE, Chen K, Henn D, Mascharak S, Talbott HE, Kim A, Nosrati F, Sivaraj D, Ransom RC, Matthews M, Khan A, Wagh D, Coller J, Gurtner GC, Wan DC, Wapnir IL, Chang HY, Norton JA, Longaker MT. Foster DS, et al. Among authors: coller j. Cancer Cell. 2022 Nov 14;40(11):1392-1406.e7. doi: 10.1016/j.ccell.2022.09.015. Epub 2022 Oct 20. Cancer Cell. 2022. PMID: 36270275 Free PMC article.
CAFs were once thought to be a relatively uniform population of matrix-producing cells, but single-cell RNA sequencing has revealed diverse CAF phenotypes. Here, we further probed CAF heterogeneity with a comprehensive multiomics approach. ...
CAFs were once thought to be a relatively uniform population of matrix-producing cells, but single-cell RNA sequencing has revealed d …
Codon optimality, bias and usage in translation and mRNA decay.
Hanson G, Coller J. Hanson G, et al. Among authors: coller j. Nat Rev Mol Cell Biol. 2018 Jan;19(1):20-30. doi: 10.1038/nrm.2017.91. Epub 2017 Oct 11. Nat Rev Mol Cell Biol. 2018. PMID: 29018283 Free PMC article. Review.
Codon optimality is a major determinant of mRNA stability.
Presnyak V, Alhusaini N, Chen YH, Martin S, Morris N, Kline N, Olson S, Weinberg D, Baker KE, Graveley BR, Coller J. Presnyak V, et al. Among authors: coller j. Cell. 2015 Mar 12;160(6):1111-24. doi: 10.1016/j.cell.2015.02.029. Cell. 2015. PMID: 25768907 Free PMC article.
We show that codon optimality is one feature that contributes greatly to mRNA stability. Genome-wide RNA decay analysis revealed that stable mRNAs are enriched in codons designated optimal, whereas unstable mRNAs contain predominately non-optimal codons. ...
We show that codon optimality is one feature that contributes greatly to mRNA stability. Genome-wide RNA decay analysis revealed that …
The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Buschauer R, Matsuo Y, Sugiyama T, Chen YH, Alhusaini N, Sweet T, Ikeuchi K, Cheng J, Matsuki Y, Nobuta R, Gilmozzi A, Berninghausen O, Tesina P, Becker T, Coller J, Inada T, Beckmann R. Buschauer R, et al. Among authors: coller j. Science. 2020 Apr 17;368(6488):eaay6912. doi: 10.1126/science.aay6912. Science. 2020. PMID: 32299921 Free PMC article.
Control of messenger RNA (mRNA) decay rate is intimately connected to translation elongation, but the spatial coordination of these events is poorly understood. ...We used a combination of cryo-electron microscopy, ribosome profiling, and mRNA stability assays to examine t …
Control of messenger RNA (mRNA) decay rate is intimately connected to translation elongation, but the spatial coordination of these e …
Codon optimality-mediated mRNA degradation: Linking translational elongation to mRNA stability.
Bae H, Coller J. Bae H, et al. Among authors: coller j. Mol Cell. 2022 Apr 21;82(8):1467-1476. doi: 10.1016/j.molcel.2022.03.032. Mol Cell. 2022. PMID: 35452615 Free PMC article. Review.
Messenger RNA (mRNA) translation by the ribosome represents the final step of a complicated molecular dance from DNA to protein. ...
Messenger RNA (mRNA) translation by the ribosome represents the final step of a complicated molecular dance from DNA to protein. ...
72 results