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Page 1
Skin Barrier Dysfunction in Acne Vulgaris: Pathogenesis and Therapeutic Approaches.
Deng Y, Wang F, He L. Deng Y, et al. Med Sci Monit. 2024 Dec 13;30:e945336. doi: 10.12659/MSM.945336. Med Sci Monit. 2024. PMID: 39668545 Free PMC article. Review.
Acne vulgaris is a chronic inflammatory disease of the hair follicle-sebaceous gland unit and is the most common skin disorder worldwide. Although it can occur at any age, it predominantly affects young individuals, manifesting as comedones, papules, pustules …
Acne vulgaris is a chronic inflammatory disease of the hair follicle-sebaceous gland unit and is the most common skin disorder …
Acne, the Skin Microbiome, and Antibiotic Treatment.
Xu H, Li H. Xu H, et al. Am J Clin Dermatol. 2019 Jun;20(3):335-344. doi: 10.1007/s40257-018-00417-3. Am J Clin Dermatol. 2019. PMID: 30632097 Free PMC article. Review.
Acne vulgaris is a chronic skin disorder involving hair follicles and sebaceous glands. Multiple factors contribute to the disease, including skin microbes. The skin microbiome in the follicle is composed of a diverse group of microorganisms. Among them, Propionibac …
Acne vulgaris is a chronic skin disorder involving hair follicles and sebaceous glands. Multiple factors contribute to the dis …
The Genetics of Acne.
Van Steensel MAM. Van Steensel MAM. Ann Hum Genet. 2025 Sep;89(5):333-341. doi: 10.1111/ahg.70014. Epub 2025 Jul 21. Ann Hum Genet. 2025. PMID: 40689430 Free PMC article. Review.
It is characterized by the presence of comedones (blackheads), papules, and pustules. The condition is associated with sebaceous glands in the face and chest, which produce an oily substance called sebum. ...There are, however, several problems with this supp …
It is characterized by the presence of comedones (blackheads), papules, and pustules. The condition is associated with sebaceous …
The effect of 2% niacinamide on facial sebum production.
Draelos ZD, Matsubara A, Smiles K. Draelos ZD, et al. J Cosmet Laser Ther. 2006 Jun;8(2):96-101. doi: 10.1080/14764170600717704. J Cosmet Laser Ther. 2006. PMID: 16766489 Clinical Trial.
BACKGROUND: The presence of sebum on the face is responsible for both facial shine and the formation of comedonal and inflammatory acne lesions. Sebum control is a goal of many OTC skin care products; however, most currently available products function by absorbing sebum f …
BACKGROUND: The presence of sebum on the face is responsible for both facial shine and the formation of comedonal and inflammatory ac …
Pathogenesis of acne.
Toyoda M, Morohashi M. Toyoda M, et al. Med Electron Microsc. 2001 Mar;34(1):29-40. doi: 10.1007/s007950100002. Med Electron Microsc. 2001. PMID: 11479771 Review.
To examine the participation of neurogenic factors in the pathogenesis of acne, we quantitatively assessed the effects of neuropeptides on the morphology of sebaceous glands in vitro using electron microscopy. Substance P, which can be elicited by stress, promoted t …
To examine the participation of neurogenic factors in the pathogenesis of acne, we quantitatively assessed the effects of neuropeptides on t …
[Acne vulgaris].
Zouboulis CC. Zouboulis CC. Hautarzt. 2014 Aug;65(8):733-47; quiz 748-9. doi: 10.1007/s00105-014-2853-9. Hautarzt. 2014. PMID: 25113333 German.
These factors interrupt the natural cycling process in the sebaceous gland follicle and support the transition of microcomedones to comedones and inflammatory lesions. ...Acne is predominantly treated with combination therapy. Selecting a treatment …
These factors interrupt the natural cycling process in the sebaceous gland follicle and support the transition of microcomedon …
Selective sebaceous gland electrothermolysis as a treatment for acne: a prospective pilot study.
Lee JW, Kim BJ, Kim MN, Ahn GY, Aso H. Lee JW, et al. Int J Dermatol. 2012 Mar;51(3):339-44. doi: 10.1111/j.1365-4632.2011.05255.x. Int J Dermatol. 2012. PMID: 22348573
Although many therapeutic options exist for acne, relapse often occurs after treatment is stopped. Some preliminary evidence suggests that selective electrothermolysis of the sebaceous glands may represent a novel therapeutic intervention. This trial was cond …
Although many therapeutic options exist for acne, relapse often occurs after treatment is stopped. Some preliminary evidence suggests …
An updated review of the sebaceous gland and its role in health and diseases Part 2: Pathophysiological clinical disorders of sebaceous glands.
Shamloul G, Khachemoune A. Shamloul G, et al. Dermatol Ther. 2021 Mar;34(2):e14862. doi: 10.1111/dth.14862. Epub 2021 Feb 19. Dermatol Ther. 2021. PMID: 33571388 Review.
Sebaceous glands are sebum-secreting components of pilosebaceous units. In the second of this two-part series, we review the pathologies in which sebaceous glands are primarily and secondarily implicated. ...Sebaceous glands are secondari …
Sebaceous glands are sebum-secreting components of pilosebaceous units. In the second of this two-part series, we review the p …
Comedone formation: etiology, clinical presentation, and treatment.
Cunliffe WJ, Holland DB, Jeremy A. Cunliffe WJ, et al. Clin Dermatol. 2004 Sep-Oct;22(5):367-74. doi: 10.1016/j.clindermatol.2004.03.011. Clin Dermatol. 2004. PMID: 15556720 Review.
An important feature in the etiology of acne is the presence of pilosebaceous ductal hypercornification, which can be seen histologically as microcomedones (Fig 1) and clinically as blackheads, whiteheads, and other forms of comedones, such as macrocomedones. There is a si …
An important feature in the etiology of acne is the presence of pilosebaceous ductal hypercornification, which can be seen histologically as …
Insights into microbial dysbiosis and Cutibacterium acnes CAMP factor interactions in acne vulgaris.
Chen Q, Liu C, Tao J, Zeng W, Zhu Z, Yao C, Shang Y, Tang J, Jin T. Chen Q, et al. Microb Genom. 2025 Jul;11(7):001449. doi: 10.1099/mgen.0.001449. Microb Genom. 2025. PMID: 40668089 Free PMC article.
Acne vulgaris is a common skin condition marked by the formation of comedones, papules, pustules and nodules, with its underlying causes still not fully understood. ...Structural analysis of CAMP3 uncovered distinct pathogenic features that, alongside CAMP5, were found to …
Acne vulgaris is a common skin condition marked by the formation of comedones, papules, pustules and nodules, with its underlying cau …
74 results