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1994 1
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110 results

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Conditioned pain modulation (CPM) paradigm type affects its sensitivity as a biomarker of fibromyalgia.
Gil-Ugidos A, Vázquez-Millán A, Samartin-Veiga N, Carrillo-de-la-Peña MT. Gil-Ugidos A, et al. Sci Rep. 2024 Apr 2;14(1):7798. doi: 10.1038/s41598-024-58079-7. Sci Rep. 2024. PMID: 38565572 Free PMC article.
Fibromyalgia (FM) is a widespread chronic pain syndrome, possibly associated with the presence of central dysfunction in descending pain inhibition pathways. Conditioned Pain Modulation (CPM) has been proposed as a biomarker of FM. Noneth
Fibromyalgia (FM) is a widespread chronic pain syndrome, possibly associated with the presence of central dysfunction in desce
Influence of Transcutaneous Electrical Nerve Stimulation (TENS) on Pressure Pain Thresholds and Conditioned Pain Modulation in a Randomized Controlled Trial in Women With Fibromyalgia.
Berardi G, Dailey DL, Chimenti R, Merriwether E, Vance CGT, Rakel BA, Crofford LJ, Sluka KA. Berardi G, et al. J Pain. 2024 Jun;25(6):104452. doi: 10.1016/j.jpain.2023.12.009. Epub 2023 Dec 26. J Pain. 2024. PMID: 38154621 Free PMC article. Clinical Trial.
Transcutaneous electrical nerve stimulation (TENS) effectively reduces pain in fibromyalgia (FM). The purpose of this study was to examine the influence of TENS use on pressure pain thresholds (PPT) and conditioned pain modulation (CPM) i …
Transcutaneous electrical nerve stimulation (TENS) effectively reduces pain in fibromyalgia (FM). The purpose of this study wa …
Defective Endogenous Pain Modulation in Fibromyalgia: A Meta-Analysis of Temporal Summation and Conditioned Pain Modulation Paradigms.
O'Brien AT, Deitos A, Triñanes Pego Y, Fregni F, Carrillo-de-la-Peña MT. O'Brien AT, et al. J Pain. 2018 Aug;19(8):819-836. doi: 10.1016/j.jpain.2018.01.010. Epub 2018 Feb 15. J Pain. 2018. PMID: 29454976 Free article. Review.
To study the characteristics of temporal summation (TS) and conditioned pain modulation (CPM) in fibromyalgia (FM) patients, we systematically searched Pubmed and EMBASE for studies using TS or CPM comparing FM patients with healthy controls. ...Sensit …
To study the characteristics of temporal summation (TS) and conditioned pain modulation (CPM) in fibromyalgia (F …
Impaired conditioned pain modulation was restored after a single exercise session in individuals with and without fibromyalgia.
Alsouhibani A, Hoeger Bement M. Alsouhibani A, et al. Pain Rep. 2022 Apr 1;7(3):e996. doi: 10.1097/PR9.0000000000000996. eCollection 2022 May-Jun. Pain Rep. 2022. PMID: 35399187 Free PMC article.
INTRODUCTION: Exercise is an effective nonpharmacological intervention for individuals with fibromyalgia syndrome (FMS); however, considerable variability is observed in their pain response after a single exercise session that could be due to differences in baseline …
INTRODUCTION: Exercise is an effective nonpharmacological intervention for individuals with fibromyalgia syndrome (FMS); however, con …
Effects of strength training on conditioned pain modulation in patients with fibromyalgia: a prospective experimental study.
Menegalli-Santos L, Pontes-Silva A, Avila MA. Menegalli-Santos L, et al. Rev Assoc Med Bras (1992). 2025 Aug 8;71(7):e20250109. doi: 10.1590/1806-9282.20250109. eCollection 2025. Rev Assoc Med Bras (1992). 2025. PMID: 40802413 Free PMC article.
OBJECTIVE: The aim of this study was to evaluate the conditioned pain modulation of patients with fibromyalgia and compare it to that of healthy individuals before and after 3 months of strength training. ...Subsequently, we compared the conditioned
OBJECTIVE: The aim of this study was to evaluate the conditioned pain modulation of patients with fibromyalgia a …
How Does Conditioned Pain Modulation Influence Motor Imagery Processes in Women with Fibromyalgia Syndrome? A Cross-Sectional Study Secondary Analysis.
Riquelme-Aguado V, Di-Bonaventura S, González-Álvarez ME, Zabarte-Del Campo A, Fernández-Carnero J, Gil-Crujera A, Gómez-Esquer F, Villafañe JH. Riquelme-Aguado V, et al. J Clin Med. 2024 Dec 2;13(23):7339. doi: 10.3390/jcm13237339. J Clin Med. 2024. PMID: 39685799 Free PMC article.
Background/Objectives: Fibromyalgia syndrome (FMS) is a multifactorial pain syndrome not only characterized by widespread pain as the primary symptom but also accompanied by physical, psychological, and cognitive manifestations. Impairments in condi
Background/Objectives: Fibromyalgia syndrome (FMS) is a multifactorial pain syndrome not only characterized by widespread p
The impact of tetrahydrocannabinol on central pain modulation in chronic pain: a randomized clinical comparative study of offset analgesia and conditioned pain modulation in fibromyalgia.
Agbaria Y, Preger R, Aloush V, Ablin JN, Sharon H, Jacob G. Agbaria Y, et al. J Cannabis Res. 2025 Nov 6;7(1):86. doi: 10.1186/s42238-025-00348-x. J Cannabis Res. 2025. PMID: 41199355 Free PMC article.
BACKGROUND: Tetrahydrocannabinol (THC) has shown efficacy in alleviating chronic pain, particularly in disorders characterized by central sensitization. Offset analgesia (OA) and conditioned pain modulation (CPM) are key biomarkers used to evaluate cen …
BACKGROUND: Tetrahydrocannabinol (THC) has shown efficacy in alleviating chronic pain, particularly in disorders characterized by cen …
Patients with neuropathic pain from lumbosacral radiculopathy demonstrate similar pressure pain thresholds and conditioned pain modulation to those with fibromyalgia.
Knezevic A, Kovacevic M, Jeremic-Knezevic M, Nikolasevic Z, Tomasevic-Todorovic S, Zivanovic Z, Spasojevic T, Garipi E, Vojnovic L, Popovic D, Neblett R. Knezevic A, et al. Neurophysiol Clin. 2023 Aug;53(4):102841. doi: 10.1016/j.neucli.2022.102841. Epub 2023 Jan 28. Neurophysiol Clin. 2023. PMID: 36716611
OBJECTIVE: The purpose of the study was to evaluate pain thresholds, impairment of the endogenous pain modulatory system, and self-reported cognitive-emotional and central sensitization-related symptoms among three subject groups: a rarely studied patient cohort wit …
OBJECTIVE: The purpose of the study was to evaluate pain thresholds, impairment of the endogenous pain modulatory system, and …
Fibromyalgia is associated with hypersensitivity but not with abnormal pain modulation: evidence from QST trials and spinal fMRI.
Staud R, Godfrey MM, Stroman PW. Staud R, et al. Front Pain Res (Lausanne). 2023 Dec 5;4:1284103. doi: 10.3389/fpain.2023.1284103. eCollection 2023. Front Pain Res (Lausanne). 2023. PMID: 38116188 Free PMC article. Review.
Widespread pain and hyperalgesia are characteristics of chronic musculoskeletal pain conditions, including fibromyalgia syndrome (FM). Despite mixed evidence, there is increasing consensus that these characteristics depend on abnormal pain augmentation …
Widespread pain and hyperalgesia are characteristics of chronic musculoskeletal pain conditions, including fibromyalgia
The Link between Endogenous Pain Modulation Changes and Clinical Improvement in Fibromyalgia Syndrome: A Meta-Regression Analysis.
Pacheco-Barrios K, Filardi RM, González-González LF, Park N, Petrus FQ, Navarro-Flores A, Di-Bonaventura S, Alves LG, Queiroz F, Fregni F. Pacheco-Barrios K, et al. Biomedicines. 2024 Sep 13;12(9):2097. doi: 10.3390/biomedicines12092097. Biomedicines. 2024. PMID: 39335610 Free PMC article. Review.
Conditioned pain modulation (CPM) and temporal summation (TS) tests can measure the ability to inhibit pain in fibromyalgia syndrome (FMS) patients and its level of pain sensitization, respectively. ...Thus, the TS and CPM tests could be
Conditioned pain modulation (CPM) and temporal summation (TS) tests can measure the ability to inhibit pain in
110 results