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Condurango (Gonolobus condurango) Extract Activates Fas Receptor and Depolarizes Mitochondrial Membrane Potential to Induce ROS-dependent Apoptosis in Cancer Cells in vitro: CE-treatment on HeLa: a ROS-dependent mechanism.
Bishayee K, Mondal J, Sikdar S, Khuda-Bukhsh AR. Bishayee K, et al. J Pharmacopuncture. 2015 Sep;18(3):32-41. doi: 10.3831/KPI.2015.18.022. J Pharmacopuncture. 2015. PMID: 26389000 Free PMC article.
OBJECTIVES: Condurango (Gonolobus condurango) extract is used by complementary and alternative medicine (CAM) practitioners as a traditional medicine, including homeopathy, mainly for the treatment of syphilis. Condurango bark extract is also known to …
OBJECTIVES: Condurango (Gonolobus condurango) extract is used by complementary and alternative medicine (CAM) practitioners as …
Condurango-glycoside-A fraction of Gonolobus condurango induces DNA damage associated senescence and apoptosis via ROS-dependent p53 signalling pathway in HeLa cells.
Bishayee K, Paul A, Ghosh S, Sikdar S, Mukherjee A, Biswas R, Boujedaini N, Khuda-Bukhsh AR. Bishayee K, et al. Mol Cell Biochem. 2013 Oct;382(1-2):173-83. doi: 10.1007/s11010-013-1732-5. Epub 2013 Jun 27. Mol Cell Biochem. 2013. PMID: 23807740
Gonolobus condurango plant extract is used as an anticancer drug in some traditional systems of medicine including homeopathy, but it apparently lacks any scientific validation. Further, no detailed study is available to suggest whether condurango-glycoside-A …
Gonolobus condurango plant extract is used as an anticancer drug in some traditional systems of medicine including homeopathy, …
Evidence of an Epigenetic Modification in Cell-cycle Arrest Caused by the Use of Ultra-highly-diluted Gonolobus Condurango Extract.
Bishayee K, Sikdar S, Khuda-Bukhsh AR. Bishayee K, et al. J Pharmacopuncture. 2013 Dec;16(4):7-13. doi: 10.3831/KPI.2013.16.024. J Pharmacopuncture. 2013. PMID: 25780677 Free PMC article.
After viability assays had been performed with Condurango 30C and with a placebo, the activities of histone de-acetylase (HDAC) enzymes 1 and 2 were measured colorimetrically. ...Data on p21(WAF), p53, Akt, and STAT3 activities and a cell-cycle analysis revealed a reductio …
After viability assays had been performed with Condurango 30C and with a placebo, the activities of histone de-acetylase (HDAC) enzym …
Post-cancer Treatment with Condurango 30C Shows Amelioration of Benzo[a]pyrene-induced Lung Cancer in Rats Through the Molecular Pathway of Caspa- se-3-mediated Apoptosis Induction: -Anti-lung cancer potential of Condurango 30C in rats.
Sikdar S, Mukherjee A, Bishayee K, Paul A, Saha SK, Ghosh S, Khuda-Bukhsh AR. Sikdar S, et al. J Pharmacopuncture. 2013 Sep;16(3):11-22. doi: 10.3831/KPI.2013.16.021. J Pharmacopuncture. 2013. PMID: 25780671 Free PMC article.
After four months, the lung-cancer-bearing rats were treated with Condurango 30C for the next one (5(th)), two (5(th)-6(th)) and three (5(th)-7(th)) months, respectively, and were sacrificed at the corresponding time- points. ...CONCLUSION: The overall result validated a p …
After four months, the lung-cancer-bearing rats were treated with Condurango 30C for the next one (5(th)), two (5(th)-6(th)) and thre …
Relative Apoptosis-inducing Potential of Homeopa-thic Condurango 6C and 30C in H460 Lung Cancer Cells In vitro: -Apoptosis-induction by homeopathic Condurango in H460 cells.
Sikdar S, Kumar Saha S, Rahman Khuda-Bukhsh A. Sikdar S, et al. J Pharmacopuncture. 2014 Mar;17(1):59-69. doi: 10.3831/KPI.2014.17.008. J Pharmacopuncture. 2014. PMID: 25780691 Free PMC article.
OBJECTIVES: In homeopathy, it is claimed that more homeopathically-diluted potencies render more protective/curative effects against any disease condition. Potentized forms of Condurango are used successfully to treat digestive problems, as well as esophageal and st …
OBJECTIVES: In homeopathy, it is claimed that more homeopathically-diluted potencies render more protective/curative effects against …