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The assessment of bleeding patterns in postmenopausal women during continuous combined hormone replacement therapy: a review of methodology and recommendations for reporting of the data.
Archer DF, Pickar JH. Archer DF, et al. Climacteric. 2002 Mar;5(1):45-59. Climacteric. 2002. PMID: 11974559 Review.
METHODS: A MEDLINE search identified 18 published reports of bleeding patterns among postmenopausal women enrolled in prospective clinical trials that included a continuous combined HRT treatment arm. ...CONCLUSION: Inconsistencies among clinica …
METHODS: A MEDLINE search identified 18 published reports of bleeding patterns among postmenopausal women enrolled in prospect …
Breast and endometrial safety of micronised progesterone versus norethisterone acetate in menopausal hormone therapy (PROBES): study protocol of a double-blind randomised controlled trial.
Lundell C, Stergiopoulos N, Blomberg L, Ujvari D, Schuppe-Koistinen I, Kopp-Kallner H, Iliadis SI, Skalkidou A, Hirschberg AL. Lundell C, et al. BMJ Open. 2024 Oct 23;14(10):e082749. doi: 10.1136/bmjopen-2023-082749. BMJ Open. 2024. PMID: 39448218 Free PMC article.
Secondary outcomes are breast proliferation, endometrial histology and proliferation, bleeding pattern, gut and vaginal microbiome, hormone levels and coagulation and metabolic factors, mood, and health-related quality of life. Part 2 features an open, single-arm de …
Secondary outcomes are breast proliferation, endometrial histology and proliferation, bleeding pattern, gut and vaginal microb …
Postmenopausal uterine bleeding profiles with two forms of continuous combined hormone replacement therapy.
Johnson JV, Davidson M, Archer D, Bachmann G. Johnson JV, et al. Menopause. 2002 Jan-Feb;9(1):16-22. doi: 10.1097/00042192-200201000-00004. Menopause. 2002. PMID: 11791082 Clinical Trial.
OBJECTIVE: This study was designed to compare the bleeding profiles of conjugated equine estrogens 0.625 mg in combination with 2.5 mg medroxyprogesterone acetate (Prempro; CEE/MPA group), the most widely prescribed continuous combined hormone replacem …
OBJECTIVE: This study was designed to compare the bleeding profiles of conjugated equine estrogens 0.625 mg in combination wit …
Effective bleeding control and symptom relief by lower dose regimens of continuous combined hormone replacement therapy: a randomized comparative dose-ranging study.
Bruhat M, Rudolf K, Vaheri R, Kainulainen P, Timonen U, Viitanen A. Bruhat M, et al. Maturitas. 2001 Dec 14;40(3):259-71. doi: 10.1016/s0378-5122(01)00245-6. Maturitas. 2001. PMID: 11731187 Clinical Trial.
OBJECTIVES: We compared two different continuous combined hormone replacement therapy (HRT) regimens of estradiol valerate (E(2)V) and medroxyprogesterone acetate (MPA) with a combination of micronized estradiol (E(2)) and norethisterone acetate (NETA) …
OBJECTIVES: We compared two different continuous combined hormone replacement therapy (HRT) regimens of estradiol valer …
Hormonal replacement regimens and bleeding.
Dören M. Dören M. Maturitas. 2000 Jan;34 Suppl 1:S17-23. doi: 10.1016/s0378-5122(99)00069-9. Maturitas. 2000. PMID: 10759060 Review.
It is almost impossible to decide which combination of an estrogen and a progestogen seems to be optimal as individual tolerance of HRT may very well limit acceptability despite metabolic benefits and proven endometrial safety of a given combination. ...It is …
It is almost impossible to decide which combination of an estrogen and a progestogen seems to be optimal as individual tolerance of …
Can endometrial protection be inferred from the bleeding pattern on combined cyclical hormone replacement therapy.
Burch D, Bieshuevel E, Smith S, Fox H. Burch D, et al. Maturitas. 2000 Feb 15;34(2):155-60. doi: 10.1016/s0378-5122(99)00101-2. Maturitas. 2000. PMID: 10714910 Clinical Trial.
There were two cases of proliferative and one of hyperplastic endometrium, with no characteristic bleeding pattern. CONCLUSION: Combined sequential HRT with progestogen given for 12-14 days very rarely fails to protect the endometrium. Such failures ca …
There were two cases of proliferative and one of hyperplastic endometrium, with no characteristic bleeding pattern. CONCLUSION …
The role of antiandrogens in hormone replacement therapy.
Schneider HP. Schneider HP. Climacteric. 2000 Dec;3 Suppl 2:21-7. Climacteric. 2000. PMID: 11379383 Review.
Dienogest, on the other hand, will soon be introduced in a continuous combined HRT. Dienogest has a 17 alpha-cyanomethyl group instead of the 17 alpha-ethinyl group typical of the common 19-nortestosterone derivatives. ...A fixed formulation containing 2 mg e …
Dienogest, on the other hand, will soon be introduced in a continuous combined HRT. Dienogest has a 17 alpha-cyanomethy …
Continuous combined hormone replacement therapy compared with tibolone.
Al-Azzawi F, Wahab M, Habiba M, Akkad A, Mason T. Al-Azzawi F, et al. Obstet Gynecol. 1999 Feb;93(2):258-64. doi: 10.1016/s0029-7844(98)00403-7. Obstet Gynecol. 1999. PMID: 9932566 Clinical Trial.
OBJECTIVE: To compare relief of vasomotor symptoms, changes in lipoproteins, and bleeding patterns in postmenopausal women receiving either continuous combined hormone replacement therapy (HRT) of estradiol valerate and norethisterone or tibolon …
OBJECTIVE: To compare relief of vasomotor symptoms, changes in lipoproteins, and bleeding patterns in postmenopausal women rec …
Regulation of estrogen/progestogen receptors in the endometrium.
Casper RF. Casper RF. Int J Fertil Menopausal Stud. 1996 Jan-Feb;41(1):16-21. Int J Fertil Menopausal Stud. 1996. PMID: 8673152 Review.
In order to prevent bleeding, continuous combined estrogen and progestin HRT has been utilized. However, most publications report irregular breakthrough bleeding in a majority of patients receiving the continuous HRT regimen. ...Fu …
In order to prevent bleeding, continuous combined estrogen and progestin HRT has been utilized. However, most pu …
Continuous combined hormone replacement therapy and its effects.
Sturdee DW. Sturdee DW. Hosp Med. 1999 Aug;60(8):584-7. doi: 10.12968/hosp.1999.60.8.1180. Hosp Med. 1999. PMID: 10621815 Review.
The cessation of menstruation at the menopause is a great relief for most women. Hormone replacement therapy (HRT) in sequential regimens re-creates a monthly cycle and period-type bleeds, which are a major cause for dissatisfaction, especially for older, postmenopa …
The cessation of menstruation at the menopause is a great relief for most women. Hormone replacement therapy (HRT) in sequential regi …
47 results