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Year Number of Results
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193 results

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Page 1
Small-Fiber Neuropathy: An Etiology-Oriented Review.
Furia A, Liguori R, Donadio V. Furia A, et al. Brain Sci. 2025 Feb 6;15(2):158. doi: 10.3390/brainsci15020158. Brain Sci. 2025. PMID: 40002491 Free PMC article. Review.
BACKGROUND: Small-fiber neuropathy (SFN), affecting Adelta or C nerve fibers, is characterized by alterations of pain and temperature sensation, as well as autonomic dysfunction. ...OBJECTIVES: Many different etiologies may underlie small-fiber …
BACKGROUND: Small-fiber neuropathy (SFN), affecting Adelta or C nerve fibers, is characterized by alterations of pain a …
Corneal Confocal Microscopy in the Diagnosis of Small Fiber Neuropathy: Faster, Easier, and More Efficient Than Skin Biopsy?
Lukashenko MV, Gavrilova NY, Bregovskaya AV, Soprun LA, Churilov LP, Petropoulos IN, Malik RA, Shoenfeld Y. Lukashenko MV, et al. Pathophysiology. 2021 Dec 26;29(1):1-8. doi: 10.3390/pathophysiology29010001. Pathophysiology. 2021. PMID: 35366285 Free PMC article. Review.
Chronic pain may affect 30-50% of the world's population and an important cause is small fiber neuropathy (SFN). Recent research suggests that autoimmune diseases may be one of the most common causes of small nerve fiber damage. ...Corneal …
Chronic pain may affect 30-50% of the world's population and an important cause is small fiber neuropathy (SFN). Recent …
Corneal Confocal Microscopy to Image Small Nerve Fiber Degeneration: Ophthalmology Meets Neurology.
Petropoulos IN, Bitirgen G, Ferdousi M, Kalteniece A, Azmi S, D'Onofrio L, Lim SH, Ponirakis G, Khan A, Gad H, Mohammed I, Mohammadi YE, Malik A, Gosal D, Kobylecki C, Silverdale M, Soran H, Alam U, Malik RA. Petropoulos IN, et al. Front Pain Res (Lausanne). 2021 Aug 19;2:725363. doi: 10.3389/fpain.2021.725363. eCollection 2021. Front Pain Res (Lausanne). 2021. PMID: 35295436 Free PMC article. Review.
Neuropathic pain has multiple etiologies, but a major feature is small fiber dysfunction or damage. Corneal confocal microscopy (CCM) is a rapid non-invasive ophthalmic imaging technique that can image small nerve fibers in the cornea …
Neuropathic pain has multiple etiologies, but a major feature is small fiber dysfunction or damage. Corneal confocal …
Assessing Corneal Confocal Microscopy and Other Small Fiber Measures in Diabetic Polyneuropathy.
Gylfadottir SS, Itani M, Kristensen AG, Nyengaard JR, Sindrup SH, Jensen TS, Finnerup NB, Karlsson P. Gylfadottir SS, et al. Neurology. 2023 Apr 18;100(16):e1680-e1690. doi: 10.1212/WNL.0000000000206902. Epub 2023 Feb 7. Neurology. 2023. PMID: 36750383 Free PMC article.
Corneal confocal microscopy (CCM) has been introduced as a tool to detect DPN. However, it is unclear if CCM can reliably be used to diagnose DPN and how the technique compares with other commonly used measures of small fiber damage, such as IEN …
Corneal confocal microscopy (CCM) has been introduced as a tool to detect DPN. However, it is unclear if CCM can reliab …
[Corneal confocal microscopy detects small-fiber neuropathy in patients with amyotrophic lateral sclerosis].
Wang HL, Fan DS, Zhang S, Liu ZY. Wang HL, et al. Zhonghua Nei Ke Za Zhi. 2022 Jan 1;61(1):77-81. doi: 10.3760/cma.j.cn112138-20210207-00114. Zhonghua Nei Ke Za Zhi. 2022. PMID: 34979774 Chinese.
Objective: To investigate small fiber neuropathy in patients with amyotrophic lateral sclerosis (ALS) by corneal confocal microscopy. ...Four parameters, such as nerve fiber length (NFL), nerve branch density (NBD), nerve fiber …
Objective: To investigate small fiber neuropathy in patients with amyotrophic lateral sclerosis (ALS) by corneal …
Corneal nerves in diabetes-The role of the in vivo corneal confocal microscopy of the subbasal nerve plexus in the assessment of peripheral small fiber neuropathy.
Roszkowska AM, Licitra C, Tumminello G, Postorino EI, Colonna MR, Aragona P. Roszkowska AM, et al. Surv Ophthalmol. 2021 May-Jun;66(3):493-513. doi: 10.1016/j.survophthal.2020.09.003. Epub 2020 Sep 19. Surv Ophthalmol. 2021. PMID: 32961210 Review.
The quantitative analysis of nerve fibers can be performed with in vivo corneal confocal microscopy considering the main parameters such as corneal nerve fibers length, corneal nerve fibers density, corneal nerve branching density, tortuo …
The quantitative analysis of nerve fibers can be performed with in vivo corneal confocal microscopy considering the mai …
The diagnostic challenge of small fibre neuropathy: clinical presentations, evaluations, and causes.
Terkelsen AJ, Karlsson P, Lauria G, Freeman R, Finnerup NB, Jensen TS. Terkelsen AJ, et al. Lancet Neurol. 2017 Nov;16(11):934-944. doi: 10.1016/S1474-4422(17)30329-0. Lancet Neurol. 2017. PMID: 29029847 Review.
Additional tests, such as those measuring small fibre-related evoked potentials and corneal confocal microscopy, might contribute to a better understanding of these neuropathies. Biochemical markers can also help in screening patients for the presence …
Additional tests, such as those measuring small fibre-related evoked potentials and corneal confocal microscopy, …
Corneal confocal microscopy detects small nerve fibre damage in patients with painful diabetic neuropathy.
Kalteniece A, Ferdousi M, Azmi S, Mubita WM, Marshall A, Lauria G, Faber CG, Soran H, Malik RA. Kalteniece A, et al. Sci Rep. 2020 Feb 25;10(1):3371. doi: 10.1038/s41598-020-60422-7. Sci Rep. 2020. PMID: 32099076 Free PMC article.
Neuropathic pain is believed to arise from damage to nociceptive C fibres in diabetic neuropathy (DN). We have utilised corneal confocal microscopy (CCM) to quantify the severity of small nerve fibre damage in relation to the severity of neuropa …
Neuropathic pain is believed to arise from damage to nociceptive C fibres in diabetic neuropathy (DN). We have utilised corneal …
Corneal confocal microscopy: a novel biomarker of small fibre neuropathy in SLE.
Gharib MH, Ponirakis G, Dafaalla SOM, Gad H, Elgassim E, Zaghloul HB, Khan A, Petropoulos IN, Bitirgen G, Emadi SA, Malik RA. Gharib MH, et al. Lupus Sci Med. 2025 Oct 23;12(2):e001645. doi: 10.1136/lupus-2025-001645. Lupus Sci Med. 2025. PMID: 41130614 Free PMC article.
OBJECTIVE: Small fibre neuropathy (SFN) is an under-recognised complication of SLE that contributes to chronic pain and reduced quality of life. We assessed the utility of corneal confocal microscopy (CCM) for identifying small fib …
OBJECTIVE: Small fibre neuropathy (SFN) is an under-recognised complication of SLE that contributes to chronic pain and …
Small fibre neuropathy.
Cazzato D, Lauria G. Cazzato D, et al. Curr Opin Neurol. 2017 Oct;30(5):490-499. doi: 10.1097/WCO.0000000000000472. Curr Opin Neurol. 2017. PMID: 28665811 Review.
PURPOSE OF REVIEW: To provide a review on the state-of-art of clinical features, diagnostics, genetics and treatments of small fibre neuropathy (SFN). RECENT FINDINGS: The spectrum of clinical features has been widened from the classical presentation of burni …
PURPOSE OF REVIEW: To provide a review on the state-of-art of clinical features, diagnostics, genetics and treatments of small fib …
193 results