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Page 1
Diagnostic performance of coronary CTA versus exercise electrocardiography in acute chest pain: A propensity score-matched study in the emergency department.
Marchetti A, Moliterno E, Rovere G, Giarletta L, Perazzolo A, Amatulli D, De Vita A, Muciaccia M, Lauriero F, Savino G, Larici AR, Merlino B, Covino M, Lanza GA, Liuzzo G, Franceschi F, Burzotta F, Natale L, Marano R. Marchetti A, et al. Eur J Radiol Open. 2026 Feb 1;16:100734. doi: 10.1016/j.ejro.2026.100734. eCollection 2026 Jun. Eur J Radiol Open. 2026. PMID: 41675917 Free PMC article.
PURPOSE: To compare the clinical impact and operational efficiency of exercise electrocardiography (ex-ECG) and coronary CT angiography (CCTA) in the diagnostic-therapeutic care pathway of patients presenting to the Emergency Department (ED) with acute chest
PURPOSE: To compare the clinical impact and operational efficiency of exercise electrocardiography (ex-ECG) and coronary CT an …
Efficacy of Coronary Computed Tomography Angiography Versus Nuclear Perfusion Stress in Preventing Downstream Imaging and Prolonged Inpatient Length of Stay in Low to Medium Risk Patients With Chest Pain.
Alonso M, Neicheril RK, Shettigar S, Lavina A, Seijo de Armas Y, Carter A, Liang H, Alonso A, Piotrkowski JS. Alonso M, et al. Cureus. 2022 Jul 27;14(7):e27326. doi: 10.7759/cureus.27326. eCollection 2022 Jul. Cureus. 2022. PMID: 36042990 Free PMC article.
Background The first-line imaging for low to medium-risk patients presenting to the emergency department with stable chest pain is often a matter of debate. Chest pain is the second most common presentation to the emergency department. ...Among these …
Background The first-line imaging for low to medium-risk patients presenting to the emergency department with stable chest pain
Survival After Initial Stress Testing vs Anatomic Testing in Suspected Coronary Artery Disease: Long-Term Follow-Up of the PROMISE Randomized Clinical Trial.
Douglas PS, Stebbins A, Foldyna B, Patel MR, Mark DB, Lu MT, Hoffmann U, Shah SH, Martinez B, Alhanti B, Pagidipati N. Douglas PS, et al. JAMA Cardiol. 2025 Oct 1;10(10):1050-1054. doi: 10.1001/jamacardio.2025.2882. JAMA Cardiol. 2025. PMID: 40864459 Clinical Trial.
OBJECTIVE: To determine long-term outcomes in patients randomized to functional (stress) vs anatomic (coronary computed tomographic angiography [CTA]) initial testing. ...RESULTS: At enrollment, mean (SD) participant age was 61 (8) years, 5270 particip …
OBJECTIVE: To determine long-term outcomes in patients randomized to functional (stress) vs anatomic (coronary computed …
A comparison of coronary CTA and stress testing using high-efficiency SPECT MPI for the evaluation of chest pain in the emergency department.
Duvall WL, Savino JA, Levine EJ, Baber U, Lin JT, Einstein AJ, Hermann LK, Henzlova MJ. Duvall WL, et al. J Nucl Cardiol. 2014 Apr;21(2):305-18. doi: 10.1007/s12350-013-9823-y. Epub 2013 Dec 6. J Nucl Cardiol. 2014. PMID: 24310280
We compared CTA to stress testing with modern SPECT MPI using high-efficiency CZT cameras and stress-first protocols in an ED population. ...There was no significant difference in cardiac return visits to the ED (5.7% CTA vs 4.3% stress t …
We compared CTA to stress testing with modern SPECT MPI using high-efficiency CZT cameras and stress-first protocols in …
Safety of coronary CT angiography and functional testing for stable chest pain in the PROMISE trial: A randomized comparison of test complications, incidental findings, and radiation dose.
Lu MT, Douglas PS, Udelson JE, Adami E, Ghoshhajra BB, Picard MH, Roberts R, Lee KL, Einstein AJ, Mark DB, Velazquez EJ, Carter W, Ridner M, Al-Khalidi HR, Hoffmann U. Lu MT, et al. J Cardiovasc Comput Tomogr. 2017 Sep-Oct;11(5):373-382. doi: 10.1016/j.jcct.2017.08.005. Epub 2017 Aug 15. J Cardiovasc Comput Tomogr. 2017. PMID: 28838846 Free PMC article. Clinical Trial.
BACKGROUND: Coronary computed tomography angiography (CTA) and functional testing strategies for stable chest pain yield similar outcomes; one aspect that may guide test choice is safety. METHODS: We compared test safety (test comp …
BACKGROUND: Coronary computed tomography angiography (CTA) and functional testing strategies for stable chest pain
Cost-effectiveness Analysis of Anatomic vs Functional Index Testing in Patients With Low-Risk Stable Chest Pain.
Karády J, Mayrhofer T, Ivanov A, Foldyna B, Lu MT, Ferencik M, Pursnani A, Salerno M, Udelson JE, Mark DB, Douglas PS, Hoffmann U. Karády J, et al. JAMA Netw Open. 2020 Dec 1;3(12):e2028312. doi: 10.1001/jamanetworkopen.2020.28312. JAMA Netw Open. 2020. PMID: 33315111 Free PMC article. Clinical Trial.
IMPORTANCE: Both noninvasive anatomic and functional testing strategies are now routinely used as initial workup in patients with low-risk stable chest pain (SCP). OBJECTIVE: To determine whether anatomic approaches (ie, coronary computed tomography angiograp …
IMPORTANCE: Both noninvasive anatomic and functional testing strategies are now routinely used as initial workup in patients with low-risk s …
CT Angiography-derived fractional flow reserve in the emergency department: Insights from a matched cohort analysis.
Vecsey-Nagy M, Hagar MT, Schoepf UJ, Osoria-Velasquez J, Griggers JI, Matuskowitz AJ, Wenderoth A, Emrich T, Varga-Szemes A. Vecsey-Nagy M, et al. Eur J Radiol. 2026 Feb;195:112556. doi: 10.1016/j.ejrad.2025.112556. Epub 2025 Nov 19. Eur J Radiol. 2026. PMID: 41275631 Free article.
PURPOSE: The feasibility of CT angiography (CTA)-based fractional flow reserve (CT-FFR) has been documented in acute chest pain (ACP). ...CONCLUSIONS: While the utilization of CT-FFR in ACP does increase ED LOS and associated healthcare costs, the selection o …
PURPOSE: The feasibility of CT angiography (CTA)-based fractional flow reserve (CT-FFR) has been documented in acute chest
Major adverse cardiac events after emergency department evaluation of chest pain patients with advanced testing: Systematic review and meta-analysis.
Mehta P, McDonald S, Hirani R, Good D, Diercks D. Mehta P, et al. Acad Emerg Med. 2022 Jun;29(6):748-764. doi: 10.1111/acem.14407. Epub 2021 Nov 23. Acad Emerg Med. 2022. PMID: 34741781
OBJECTIVES: Our primary objective was to describe the risk of major adverse cardiac events (MACE) at 1, 6, and 12 months after a negative coronary computed tomography angiogram (cCTA), electrocardiogram (ECG) stress test, stress echocardiography, and m …
OBJECTIVES: Our primary objective was to describe the risk of major adverse cardiac events (MACE) at 1, 6, and 12 months after a negative …
Cardiac Investigation Trends Among Primary Care Physicians: A Paradigm Shift.
Ni TT, Afgani FJ, Brenna CTA, Patel N, Nguyen ET. Ni TT, et al. Can Assoc Radiol J. 2023 May;74(2):305-313. doi: 10.1177/08465371221139825. Epub 2022 Nov 24. Can Assoc Radiol J. 2023. PMID: 36421010 Free article.
OBJECTIVE: While numerous recent guidelines support coronary computed tomography angiography (CTA) as a first-line test for stable chest pain, it remains underutilized by primary care physicians (PCPs). ...Coronary CTA was associat …
OBJECTIVE: While numerous recent guidelines support coronary computed tomography angiography (CTA) as a first-line test
Single resting hsTnT level predicts abnormal myocardial stress test in acute chest pain patients with normal initial standard troponin.
Ahmed W, Schlett CL, Uthamalingam S, Truong QA, Koenig W, Rogers IS, Blankstein R, Nagurney JT, Tawakol A, Januzzi JL, Hoffmann U. Ahmed W, et al. JACC Cardiovasc Imaging. 2013 Jan;6(1):72-82. doi: 10.1016/j.jcmg.2012.08.014. JACC Cardiovasc Imaging. 2013. PMID: 23328564 Free PMC article.
CONCLUSIONS: In patients with acute chest pain, myocardial perfusion abnormalities and coronary artery disease are predicted by resting hsTnT levels. Prospective evaluations are warranted to confirm whether resting hsTnT could serve as a powerful triage tool …
CONCLUSIONS: In patients with acute chest pain, myocardial perfusion abnormalities and coronary artery disease are pred …
29 results