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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1969 1
1971 1
1972 1
1974 2
1977 1
1980 2
1981 1
1982 3
1983 2
1984 7
1985 5
1986 4
1987 7
1988 5
1989 4
1990 6
1991 8
1992 11
1993 7
1994 6
1995 5
1996 17
1997 12
1998 12
1999 16
2000 19
2001 22
2002 14
2003 15
2004 18
2005 22
2006 30
2007 40
2008 41
2009 55
2010 60
2011 57
2012 59
2013 61
2014 57
2015 60
2016 56
2017 62
2018 57
2019 63
2020 66
2021 63
2022 50
2023 51
2024 59
2025 74
2026 32

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1,258 results

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Page 1
Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain.
Noseda R, Burstein R. Noseda R, et al. Pain. 2013 Dec;154 Suppl 1:S44-53. doi: 10.1016/j.pain.2013.07.021. Epub 2013 Jul 25. Pain. 2013. PMID: 23891892 Review.
Data supporting the activation and sensitization of the trigeminovascular system include the progressive development of cephalic and whole-body cutaneous allodynia during a migraine attack. In addition, structural and functional alterations include the presence of subcorti …
Data supporting the activation and sensitization of the trigeminovascular system include the progressive development of cephalic and whole-b …
Therapeutic implications of cortical spreading depression models in migraine.
Takizawa T, Ayata C, Chen SP. Takizawa T, et al. Prog Brain Res. 2020;255:29-67. doi: 10.1016/bs.pbr.2020.05.009. Epub 2020 Jun 27. Prog Brain Res. 2020. PMID: 33008510 Review.
Migraine is among the most common and disabling neurological diseases in the world. Cortical spreading depression (CSD) is a wave of near-complete depolarization of neurons and glial cells that slowly propagates along the cortex creating the perception …
Migraine is among the most common and disabling neurological diseases in the world. Cortical spreading depression …
A Phase-by-Phase Review of Migraine Pathophysiology.
Dodick DW. Dodick DW. Headache. 2018 May;58 Suppl 1:4-16. doi: 10.1111/head.13300. Headache. 2018. PMID: 29697154 Review.
In one-third of patients, an aura phase may occur during some attacks and likely correlates with a cortical spreading depression-like event; a slowly propagating wave of neuronal and glial cell depolarization and hyperpolarization. Improved characterization o …
In one-third of patients, an aura phase may occur during some attacks and likely correlates with a cortical spreading depre …
Cortical spreading depression and migraine.
Eikermann-Haerter K, Ayata C. Eikermann-Haerter K, et al. Curr Neurol Neurosci Rep. 2010 May;10(3):167-73. doi: 10.1007/s11910-010-0099-1. Curr Neurol Neurosci Rep. 2010. PMID: 20425031 Review.
Cortical spreading depression, a slowly propagating wave of transient neuronal and glial depolarization, is widely accepted as the electrophysiologic substrate of migraine aura and a trigger for headache. Recent clinical and experimental evidence reinf …
Cortical spreading depression, a slowly propagating wave of transient neuronal and glial depolarization, is widely acce …
Cortical spreading depression as a site of origin for migraine: Role of CGRP.
Close LN, Eftekhari S, Wang M, Charles AC, Russo AF. Close LN, et al. Cephalalgia. 2019 Mar;39(3):428-434. doi: 10.1177/0333102418774299. Epub 2018 Apr 25. Cephalalgia. 2019. PMID: 29695168 Free PMC article. Review.
PROBLEM: One potential triggering mechanism in migraine with aura is cortical spreading depression, which can activate the trigeminal nociceptive system both peripherally and centrally in animal models. ...However, recent data suggest several potential …
PROBLEM: One potential triggering mechanism in migraine with aura is cortical spreading depression, which can ac …
Cortical spreading depression and migraine.
Charles AC, Baca SM. Charles AC, et al. Nat Rev Neurol. 2013 Nov;9(11):637-44. doi: 10.1038/nrneurol.2013.192. Epub 2013 Sep 17. Nat Rev Neurol. 2013. PMID: 24042483 Review.
Cortical spreading depression (CSD), a slowly propagated wave of depolarization followed by suppression of brain activity, is a remarkably complex event that involves dramatic changes in neural and vascular function. ...Considerable uncertainty about the role …
Cortical spreading depression (CSD), a slowly propagated wave of depolarization followed by suppression of brain activi …
Cortical spreading depression in migraine.
Lauritzen M. Lauritzen M. Cephalalgia. 2001 Sep;21(7):757-60. doi: 10.1111/j.1468-2982.2001.00244.x. Cephalalgia. 2001. PMID: 11595007 Review.
Cortical spreading depression (CSD) is associated with a dramatic failure of brain ion homeostasis as well as efflux of excitatory amino acids from nerve cells and increased energy metabolism. There is strong clinical and experimental evidence to suggest that …
Cortical spreading depression (CSD) is associated with a dramatic failure of brain ion homeostasis as well as efflux of …
Cortical spreading depression in migraine-time to reconsider?
McComas AJ, Upton AR. McComas AJ, et al. Arq Neuropsiquiatr. 2015 Aug;73(8):714-21. doi: 10.1590/0004-282X20150094. Arq Neuropsiquiatr. 2015. PMID: 26222365 Free article. Review.
New evidence concerning the pathophysiology of migraine has come from the results of therapeutic transcranial magnetic stimulation (tTMS). The instantaneous responses to single pulses applied during the aura or headache phase, together with a number of other observations, …
New evidence concerning the pathophysiology of migraine has come from the results of therapeutic transcranial magnetic stimulation (t …
Role of cortical spreading depression in the pathophysiology of migraine.
Cui Y, Kataoka Y, Watanabe Y. Cui Y, et al. Neurosci Bull. 2014 Oct;30(5):812-22. doi: 10.1007/s12264-014-1471-y. Epub 2014 Sep 28. Neurosci Bull. 2014. PMID: 25260797 Free PMC article. Review.
Migraine aura is thought to be a result of the neurovascular phenomenon of cortical spreading depression (SD), a self-propagating wave of depolarization that spreads across the cerebral cortex. ...Although several issues remain to be resolved, recent e …
Migraine aura is thought to be a result of the neurovascular phenomenon of cortical spreading depression (SD), a …
Cortical spreading depression as a target for anti-migraine agents.
Costa C, Tozzi A, Rainero I, Cupini LM, Calabresi P, Ayata C, Sarchielli P. Costa C, et al. J Headache Pain. 2013 Jul 23;14(1):62. doi: 10.1186/1129-2377-14-62. J Headache Pain. 2013. PMID: 23879550 Free PMC article. Review.
Cortical SD (CSD) is considered the neurophysiological correlate of migraine aura. It is characterized by massive increases in both extracellular K+ and glutamate, as well as rises in intracellular Na+ and Ca2+. ...Moreover, CSD is associated with changes in cort …
Cortical SD (CSD) is considered the neurophysiological correlate of migraine aura. It is characterized by massive increases in …
1,258 results